For Gas Chromatography Patents (Class 73/23.22)
  • Patent number: 9989485
    Abstract: Prior to the measurements a first volume element is specified in a porous material sample in order to record the distribution of pore volume characteristics and matrix thermal conductivity along a surface of the porous material sample. A second volume element is set for the record of a thermal conductivity distribution along the surface of the sample with the dimensions equal or close to the dimensions of the first volume element for the record of the pore volume characteristics' and matrix thermal conductivity. The porous material sample is subsequently saturated with at least two fluids with known different thermal conductivities. After each saturation a sample thermal conductivity is measured in each volume element of the sample equal to the second volume element and pore volume characteristics and the porous material matrix thermal conductivity are determined for each volume element of the sample corresponding to the first volume element.
    Type: Grant
    Filed: June 26, 2012
    Date of Patent: June 5, 2018
    Assignee: SCHLUMBERGER TECHNOLOGY CORPORATION
    Inventors: Yury Anatolievich Popov, Irina Olegovna Bayuk, Anton Vladimirovich Parshin
  • Patent number: 9678046
    Abstract: A system and method for thermal gradient gas chromatography wherein a front or injection end of a column is heated to a higher temperature than a back or detector end to thereby create a thermal gradient having a profile that is substantially monotonically non-increasing and has a positive second derivative, and then providing a heat source to raise the thermal gradient and cause it to remain stationary or to travel through the column while maintaining a desired profile.
    Type: Grant
    Filed: September 16, 2014
    Date of Patent: June 13, 2017
    Assignee: BRIGHAM YOUNG UNIVERSITY
    Inventors: H. Dennis Tolley, Anzi Wang, Samuel E. Tolley, Milton L. Lee, Aaron R. Hawkins
  • Patent number: 8841611
    Abstract: A gas chromatograph-mass spectrometer (GC-MS) system includes a multi-capillary GC column coupled to a mass analyzer through an ionization interface. The ionization interface includes an ionization device and an ion guide configured for receiving a high-capacity gas-sample flow from the GC column and transmitting a compressed ion beam to the mass analyzer. The ion beam may be converging.
    Type: Grant
    Filed: October 15, 2013
    Date of Patent: September 23, 2014
    Assignee: Agilent Technologies, Inc.
    Inventors: Gangqiang Li, Maozi Liu
  • Patent number: 8771597
    Abstract: The invention relates to an apparatus for the determination of a concentration of a component to be measured in a gas, comprising a light source, a wavelength selection unit, a measurement cuvette, a reference cuvette arranged in the optical beam path in parallel thereto, at least one light receiver and an evaluation unit which determines the concentration from the signals of the light receiver, wherein the gas to be analyzed is supplied to the measurement cuvette, on the one hand, and, on the other hand, to the reference cuvette via an absorption apparatus which includes a substance which completely absorbs the component to be measured. Further, the component to be measured is H2S and a wavelength selection unit is provided for the selection of an absorption wavelength.
    Type: Grant
    Filed: May 15, 2012
    Date of Patent: July 8, 2014
    Assignee: SICK AG
    Inventors: Michael Zochbauer, Carsten Rogge, Dominikus Huttner
  • Patent number: 8431889
    Abstract: The present invention relates to a method for repetitive chemical analysis of a gas flow, wherein said gas flow consists of a carrier gas and gaseous chemical compounds, comprising the following method steps: feeding said gas flow to a gas chromatographic separation column by means of a feeding device; collecting at least a part of said gaseous chemical compounds for a defined time period by means of a thermally based collecting device which is coupled to said gas chromatographic separation column and/or said feeding device; releasing said collected gaseous chemical compounds in a temporally focused manner by means of said thermally based collecting device; separating said released gaseous chemical compounds by means of said gas chromatographic separation column; and analyzing said separated gaseous chemical compounds by means of an analyzer. The present invention further relates to a device for performing such a method.
    Type: Grant
    Filed: March 19, 2012
    Date of Patent: April 30, 2013
    Assignee: Helmholtz Zentrum Muenchen Deutsches Forschungszentrum fuer Gesundheit und Umwelt (GmbH)
    Inventors: Ralf Zimmermann, Mohammad Reza Saraji-Bozorgzad, Markus Simon Eschner, Thomas Maximilian Groeger
  • Patent number: 8371152
    Abstract: A device for conserving helium gas in a gas chromatograph system is characterized in that during the majority of an analytical separation, helium is used as the carrier gas while an auxiliary non-helium gas is used to pressurize the inlet and provide for septum purge and split vent flow. Prior an injection period, a coaxial helium flow is established at the column entrance wherein the coaxial helium flow is less than the column flow. Following the injection and sample transfer period, a coaxial helium flow is established wherein the flow is greater than the column flow.
    Type: Grant
    Filed: October 27, 2010
    Date of Patent: February 12, 2013
    Assignee: Thermo Finnigan LLC
    Inventors: Edward B. McCauley, Paolo Magni
  • Patent number: 8322189
    Abstract: The present invention is an improvement to two-dimensional comprehensive gas chromatography. The improvement is a one valve switching modulator connecting the two separation columns. The valve includes either a two position eight-port valve or a two position twelve-port valve, and two transfer lines.
    Type: Grant
    Filed: August 14, 2009
    Date of Patent: December 4, 2012
    Assignee: ExxonMobil Research and Engineering Company
    Inventor: Frank C. Wang
  • Patent number: 8264326
    Abstract: A biometrics sensor includes a portion for sucking air, a molecular sieve portion for selectively passing or adsorbing specific gas contained in the air, a gas detecting section for detecting the concentration of gas passed through the molecular sieve or the remaining gas, and a data processing section for comparing the detection result with a prestored detection result, wherein the gas detecting section selectively detects predetermined gas, and the data processing section performs determination or probabilistic determination on an authentication object person by comparing the composition ratio of gas for each authentication object person with a prestored composition ratio.
    Type: Grant
    Filed: August 29, 2007
    Date of Patent: September 11, 2012
    Assignees: Kyushu University, Use Co., Ltd.
    Inventors: Kenshi Hayashi, Bunpei Yoshihiro
  • Patent number: 8237116
    Abstract: GC-MS analysis apparatus has an interface section between GC and MS sections, which is located with respect to the direction of an analyte flow downstream of the GC section and upstream of the MS section. The interface section comprises at least one membrane with at least one orifice capable of establishing a molecular flow condition in the analyte passing between the GC and MS sections through the membrane. The membrane is subjected to a pressure differential such that the pressure pa in a region located upstream of the membrane is higher than the pressure pb in a region located downstream of the membrane.
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: August 7, 2012
    Assignee: Agilent Technologies, Inc.
    Inventor: Raffaele Correale
  • Patent number: 7971470
    Abstract: A non-invasive and non-destructive apparatus and testing method for analytes in sealed containers are provided, which are especially useful for identifying bottles of wine that are contaminated with 2,4,6-trichloroanisole (TCA) without destroying the value of uncontaminated wine by opening the bottles or marring the containers or labeling. The apparatus and method are applicable to non-destructively testing any “stream-of-commerce” containers such as shampoo bottles, aerosol containers, toothpaste tubes, and soft drink cans, and other such containers for the presence of contaminants, explosives, poisons, drugs, and other dangerous or illegal materials. The method provided is orders of magnitude more sensitive than other methods, and can detect the presence of diffused substances at the nanogram per liter (parts-per-billion) level.
    Type: Grant
    Filed: April 11, 2008
    Date of Patent: July 5, 2011
    Assignee: Madison Avenue Management Company, Inc.
    Inventor: Joseph S. Broz
  • Patent number: 7906073
    Abstract: Analyzers are described that contain a detector for detecting a signal from an analyte; a heater for heating a fluid; a fluid supplier for supplying the fluid heated by the heater to the detector; and a controller for controlling the detector, the heater, and the fluid supplier. Methods for analyzing analytes are also described.
    Type: Grant
    Filed: June 30, 2003
    Date of Patent: March 15, 2011
    Assignee: Sysmex Corporation
    Inventor: Masaharu Shibata
  • Patent number: 7832253
    Abstract: A portable weather resistant gas chromatograph system with a gas chromatograph enclosure having a body and a movable door and a seal, a gas chromatograph with a frame assembly removably secured in the enclosure, a plurality of exhaust gas lines connected to the gas chromatograph, an explosion proof terminal box with circuit breakers and terminals mounted to the enclosure, a communication conduit and armored power cable between the explosion proof terminal box and the gas chromatograph, a purge gas conduit port for the gas chromatograph, a pedestal for the enclosure, and at least two lifting eyes connected to the enclosure.
    Type: Grant
    Filed: March 3, 2009
    Date of Patent: November 16, 2010
    Assignee: Solarcraft, Inc.
    Inventors: Darrell N. Haun, Donald N. Haun
  • Patent number: 7699915
    Abstract: A modified liquid impingement unit is configured to automatically maintain a volume of buffer solution within a determined range, the buffer solution used to collect airborne particles from an impinging airflow. The liquid impingement unit includes a first end of an air nozzle and a first end of a vacuum tube sealed within collection vessel. A fluid delivery tube is positioned within the vacuum tube such that a first end of the fluid delivery tube is also positioned within the sealed collection vessel. External to the sealed collection vessel, the fluid delivery tube branches from the vacuum tube through an aperture in the vacuum tube. The vacuum tube is coupled to a vacuum pump and the fluid delivery tube is coupled to a fluid pump. A control module provides control signals to the fluid pump such that the fluid pump delivers a second volume of buffer solution from a buffer solution container to the collection vessel via the fluid delivery tube.
    Type: Grant
    Filed: August 24, 2006
    Date of Patent: April 20, 2010
    Assignee: Microfluidic Systems, Inc.
    Inventor: Chun-Wah (Phil) Lin
  • Publication number: 20100050737
    Abstract: The present invention relates to a method and accompanying device for separating a known or unknown sample into one or more subsamples. By comparing the subsample's measurement profile data to the sample measurement profile data, the performance of the separation can be determined. The separation could be chromatography [such as high-performance liquid chromatography (HPLC), gas chromatography (GC), or the like], electrophoresis [such as capillary electrophoresis (CE) or the like], or another separation technique. The measurement profile data could be ultraviolet/visible (UV/Vis) spectra, mass spectra (MS), or another measurement technique.
    Type: Application
    Filed: August 27, 2009
    Publication date: March 4, 2010
    Inventor: Andrew Mark Wolters
  • Patent number: 7611901
    Abstract: A method for determining proportion of diesel fuel in a lubricating oil of a combustion engine, including: forming a mixture containing an oil sample and a C5 hydrocarbon such as a C5 alkane; injecting the mixture into the injector of a gas chromatograph; establishing a chromatograph of the sample; determining a first parameter M representative of the area of a peak associated with the C5 hydrocarbon such as a C5 alkane; determining a second parameter C representing of the area of at least one peak associated with a hydrocarbon representative of diesel fuel; and determining the proportion T of diesel fuel by a formula T = C / ( M ) - b a in which a and b are constants defining equation y=ax+b of a calibration straight line of the ratio between the second and the first parameters as a function of the proportion of diesel fuel.
    Type: Grant
    Filed: October 26, 2006
    Date of Patent: November 3, 2009
    Assignee: Renault S.A.S.
    Inventors: Eric Fitamen, Laurent Tiquet
  • Patent number: 7493795
    Abstract: The present invention provides a gas detection method and detection apparatus that provide better sensitivity and faster recovery after response than conventional gas detection methods and apparatus, by improving on these conventional methods and apparatus. The present invention is a gas detection method, in which the target gas is detected while oxygen is supplied to a sensor element 11a of a metal oxide-type gas sensor 11, wherein the target gas is detected while water vapor is supplied to the sensor element 11a, and is also a gas detection apparatus equipped with an oxygen supply means 14 for supplying oxygen to a sensor element 11a of a metal oxide-type gas sensor 11, said gas detection apparatus being provided with a water vapor supply means 15 for supplying water vapor to the sensor element 11a.
    Type: Grant
    Filed: January 19, 2005
    Date of Patent: February 24, 2009
    Assignee: Suntory Limited
    Inventors: Hajime Komura, Kazuo Onaga, Mariko Sugimura, Hiroshi Koda, Kazuyasu Iida
  • Patent number: 7496453
    Abstract: An efficient, effective and reliable method for authentication of herbal medicines (HMs) based on a novel wavelet-enhanced automated three-dimensional chromatograms classification system. The method takes advantage of the character of 3D chromatograms which appear as functional curves and the preprocessing power of wavelet transform (WT) to minimize the interferences from noises and baseline drifting of the raw data, and at the same time significantly reduces the data sizes. This compressed data retain the essential features of the original raw data, whereby leading to efficient and reliable method for identifying or authenticating herbal medicines or other chemical mixtures of great complexity.
    Type: Grant
    Filed: November 7, 2006
    Date of Patent: February 24, 2009
    Assignee: The Hong Kong Polytechnic University
    Inventor: Foo-Tim Chau
  • Patent number: 7476852
    Abstract: Embodiments of the present invention relate to detector structures for use in a micro gas analyzer, preferably in a differential setup. The detector structures may comprise one or more detector types, such as photo-ionization (PID), electron capture (ECD), ion mobility (IMS), differential mobility (DMS), ion-trap mass spectrometer (ITMS), in which all are provided with ions and electrons from one vacuum ultra violet (VUV) source. This source may also provide ions for ion-based gas pumps.
    Type: Grant
    Filed: January 10, 2006
    Date of Patent: January 13, 2009
    Assignee: Honeywell International Inc.
    Inventors: Ulrich Bonne, Teresa M. Marta, Karen M. Newstrom-Peitso
  • Patent number: 7412872
    Abstract: The present description relates to a process for measuring outgas emissions in fabrication chambers used for semiconductors, micromachines and the like. In one embodiment, the invention includes inserting a gas adsorption material into a processing chamber exhaust vent, running a process in the chamber, venting gasses in the chamber through the gas adsorption material, removing the adsorption material from the exhaust vent, and analyzing the adsorption material for gases.
    Type: Grant
    Filed: March 31, 2005
    Date of Patent: August 19, 2008
    Assignee: Intel Corporation
    Inventors: Hok-Kin Choi, Vani Thirumala
  • Patent number: 7360434
    Abstract: A pressure tap probe having a flexible probe tip that is flexible enough to seal a film cooling hole having a roughened surface such as a TBC applied around the hole. The flexible probe tip is flexible enough to deform around the film cooling hole such that an accurate pressure reading can be observed for the film cooling hole. The flexible pressure tap is used to measure the pressure at a plurality of film cooling holes on a turbine airfoil when a pressure and a flow rate of cooling air is passed through the airfoil. A plurality of film cooling holes are measured by using the flexible pressure tap to determine if the cooling passages and film cooling holes are properly sized to provide adequate cooling for the airfoil.
    Type: Grant
    Filed: December 30, 2006
    Date of Patent: April 22, 2008
    Assignee: Florida Turbine Technologies, Inc.
    Inventors: Douglas A. Hayes, John E. Ryznic
  • Patent number: 7359804
    Abstract: A system and method is provided for obtaining calibration curves for CO and CO2 during laboratory calibration of one or more remote emissions sensing (RES) instruments, and for self-calibration of on-road RES instruments to compensate for changes in background CO and CO2 column densities.
    Type: Grant
    Filed: August 25, 2005
    Date of Patent: April 15, 2008
    Assignee: Environmental Systems Products Holdings Inc.
    Inventors: Mitchell Jared Williams, Donald H. Stedman
  • Patent number: 7270020
    Abstract: The disclosure relates to instrument assemblies that can include a sample introduction port coupled to a chamber configured to receive the sample from the sample introduction port and provide analysis of the sample with a valve between the sample introduction port and the chamber. The instrument assemblies can include a septum housing assembly coupled to an analysis chamber interface with the interface including a valve and a cam rotatably mounted to the septum housing assembly and/or coupled to the valve. Analysis methods are also provided that can include introducing a sample to an instrument through both a sample introduction port and a valve coupled to the sample introduction port, and, after introducing the sample, closing the valve to seal the sample introduction port from a remainder of the instrument, with the remainder of the instrument being configured to analyze the sample after the introducing through the sample introduction port.
    Type: Grant
    Filed: June 13, 2005
    Date of Patent: September 18, 2007
    Assignee: Griffin Analytical Technologies, LLC
    Inventors: Mark Gregory, Dennis Barket, John W Grossenbacher, Anthony Cochran
  • Patent number: 7257987
    Abstract: Methods and systems for analyzing samples, such as gas samples, are described. One method comprises providing a gas sample, increasing pressure applied to the gas sample to compress the sample to a smaller volume and provide a pneumatically focused gas sample, and analyzing the pneumatically focused gas sample using any of a variety of analytical techniques. Also disclosed are systems for gas analysis, including systems for analysis of pneumatically focused, and thereby concentrated, gas samples and for analysis of particulate matter in gas samples. Analytical systems constructed within personal computer cases also are disclosed.
    Type: Grant
    Filed: February 18, 2004
    Date of Patent: August 21, 2007
    Assignee: State of Oregon acting by and through the State Board of Higher Education on behalf of Portland State University
    Inventors: Robert J. O'Brien, Thomas R. Smith
  • Patent number: 7140231
    Abstract: An evolved gas analysis system contains a first measurement step of heating a first sample containing measurement target material and non-measurement target material at a predetermined temperature programming rate and detecting the amount of gas evolved from the first sample; a second measurement step of heating a second sample achieved by excluding the measurement target material from the first sample at the same temperature increasing rate as the first measurement step, and detecting the amount of gas evolved from the second sample; and a correcting step of calculating the amount of gas evolved from the measurement target material on the basis of the detected data of the respective steps.
    Type: Grant
    Filed: August 17, 2004
    Date of Patent: November 28, 2006
    Assignee: Rigaku Corporation
    Inventors: Tadashi Arii, Yoshihiro Takata
  • Patent number: 7059112
    Abstract: An engine diagnostic system for use with an internal combustion engine coupled to a lean NOx trap with a NOx sensor coupled downstream of the trap. Degradation of the NOx sensor is determined by estimated NOx exiting the trap based on engine out NOx and various other operating conditions. When the difference between the measured NOx and estimated NOx is greater than a predetermined value for a predetermined duration, degradation is indicated.
    Type: Grant
    Filed: April 9, 2004
    Date of Patent: June 13, 2006
    Assignee: Ford Global Technologies, LLC
    Inventors: David Karl Bidner, Gopichandra Surnilla
  • Patent number: 6968729
    Abstract: The present invention comprises a method for expediting the analysis of a plurality of samples, preferably using gas chromatography. A specific embodiment comprises a dual isothermal heated zone configuration for use in combinatorial chemistry. This involves partitioning the samples into two isothermal zones, allowing detailed analysis of light components in a lower-temperature zone while heavy components are handled in a higher-temperature zone.
    Type: Grant
    Filed: February 27, 2004
    Date of Patent: November 29, 2005
    Assignee: UOP LLC
    Inventors: Arne Karlsson, Duncan E. Akporiaye, Svend A. Taftø, Ivar M. Dahl, Elisabeth M. Myhrvold, Arne L. Kvernheim
  • Patent number: 6883365
    Abstract: A focusing device for volatile and semi-volatile organic compounds in the gaseous phase, comprising a support structure, a container for said organic compounds, a cooling element and a heating element for their transfer to the analysis system, characterized in that said cooling element and said heating element are positioned in two separate regions of said support structure and form a single block movable relative to said container.
    Type: Grant
    Filed: August 7, 2001
    Date of Patent: April 26, 2005
    Assignee: Dani Strumentazione Analitica S.p.A.
    Inventor: Umberto Saini Fasanotti
  • Patent number: 6856917
    Abstract: A method of properly correcting a base line. A concept of flexibility of a base line is introduced as an input index and a gravitation is presumed between the base line and signal data which is measured, thereby constructing a method of correcting the base line which changes gentler than a change in signal with respect to time in a peak area and which is sensitive to an area where a value of the signal data is small. A base line like a natural and smooth curve which isn't easily influenced by a local change in signal such as noise or the like can be set by an input of the flexibility.
    Type: Grant
    Filed: October 28, 2003
    Date of Patent: February 15, 2005
    Assignee: Hitachi, Ltd.
    Inventors: Masahito Ito, Kisaburo Deguchi, Yoshiaki Seki
  • Patent number: 6781384
    Abstract: An electronic circuit and a method of generating an electrical discharge for an ionization detector system. The electronic circuit includes a transformer with a primary portion and a secondary portion. The circuit and method produce an electrical discharge across a set of electrodes. The discharge is stable over time and has relatively low peak currents associated therewith.
    Type: Grant
    Filed: July 24, 2001
    Date of Patent: August 24, 2004
    Assignee: Agilent Technologies, Inc.
    Inventors: Mahmoud Abdel-Rahman, Robert P. Rhodes
  • Publication number: 20040099046
    Abstract: In a gas chromatograph an injected sample for analysis is led through a separating device to separate components contained in the sample, at the end of which selected components are detected by means of a detector and quantitatively determined by means of the detector signal. A validation and furthermore an improvement in accuracy of the analysis is possible, whereby the sample (3) is non-destructively analysed by a further detector (16), before the separation device (5) and quantitatively determined with the further detector signal (17) delivered by the further detector (16) and the result of the quantitative determination of the sample (3) taken for monitoring the analysis.
    Type: Application
    Filed: August 8, 2003
    Publication date: May 27, 2004
    Applicant: SIEMENS AG
    Inventor: Friedhelm Mueller
  • Patent number: 6673644
    Abstract: A sensor is disclosed. A representative sensor includes a silicon substrate having a porous silicon region. A portion of the porous silicon region has a front contact is disposed thereon. The contact resistance between the porous silicon region and the front contact is between about 10 ohms and 100 ohms.
    Type: Grant
    Filed: October 10, 2002
    Date of Patent: January 6, 2004
    Assignee: Georgia Tech Research Corporation
    Inventors: James L. Gole, Lenward T. Seals, Peter J. Hesketh
  • Patent number: 6675107
    Abstract: A method of properly correcting a base line. A concept of flexibility of a base line is introduced as an input index and a gravitation is presumed between the base line and signal data which is measured, thereby constructing a method of correcting the base line which changes gentler than a change in signal with respect to time in a peak area and which is sensitive to an area where a value of the signal data is small. A base line like a natural and smooth curve which isn't easily influenced by a local change in signal such as noise or the like can be set by an input of the flexibility.
    Type: Grant
    Filed: December 16, 2002
    Date of Patent: January 6, 2004
    Assignees: Hitachi, Ltd., Hitachi Instruments Engineering Co., Ltd.
    Inventors: Masahito Ito, Kisaburo Deguchi, Yoshiaki Seki
  • Patent number: 6573492
    Abstract: In a spectrometric analysis method and an apparatus implementing the method, a data base storing spectral data sets of respective standard substances, which are obtained by analyzing these standard substances in advance, each spectral data set including a name of a substance, its MS1 spectral data and MS2 spectral data, is constructed; and MS2 spectral data sets obtained by MS2 analysis of a sample are compared with MS2 analysis spectral data sets stored in the data base.
    Type: Grant
    Filed: December 26, 2000
    Date of Patent: June 3, 2003
    Assignee: Hitachi, Ltd.
    Inventor: Shinji Nagai
  • Patent number: 6529836
    Abstract: A method of properly correcting a base line. A concept of flexibility of a base line is introduced as an input index and a gravitation is presumed between the base line and signal data which is measured, thereby constructing a method of correcting the base line which changes gentler than a change in signal with respect to time in a peak area and which is sensitive to an area where a value of the signal data is small. A base line like a natural and smooth curve which isn't easily influenced by a local change in signal such as noise or the like can be set by an input of the flexibility.
    Type: Grant
    Filed: August 29, 2001
    Date of Patent: March 4, 2003
    Assignees: Hitachi, Ltd., Hitachi Instruments Engineering Co., Ltd.
    Inventors: Masahito Ito, Kisaburo Deguchi, Yoshiaki Seki
  • Patent number: 6497136
    Abstract: A trace-level gas analysis apparatus having a diffusion scrubber 11 that captures atmospheric gas components and a sampling tube 10 that guides air into the diffusion scrubber 11 is provided with the cleaning means 2 for cleaning the diffusion scrubber 11 and the sampling tube 10, using a cleaning fluid 22.
    Type: Grant
    Filed: February 1, 2001
    Date of Patent: December 24, 2002
    Assignee: NEC Corporation
    Inventor: Yuuichi Satou
  • Patent number: 6494078
    Abstract: A method applies retention-time locking to the retention times and/or the column(s) void times of a target analyte(s) being eluted thru a multidimensional gas chromatography system. Retention time locking is applied to both standard and comprehensive multidimensional gas chromatography via the steps of adjusting column(s) head pressure in a locking multidimensional gas chromatograph system such that the measured retention times and/or void times match the known accepted. Retention time locking may be applied to either or both of the columns in a multidimensional gas chromatography system. Additionally, if the multidimensional system contains more than two columns in series, retention time locking can be applied to any or all of the columns as required.
    Type: Grant
    Filed: June 25, 2001
    Date of Patent: December 17, 2002
    Assignee: Agilent Technologies, Inc.
    Inventor: Matthew S. Klee
  • Patent number: 6386014
    Abstract: A system for determining the energy and volume delivered by a flowing natural gas carried within a pipeline based on BTU content analysis of the natural gas using a micro-miniature gas chromatograph. By monitoring key parameters of the flowing natural gas, such as temperature, pressure, flow rate, and BTU content, the system 110 accurately determines the total energy and total volume delivered by the flowing natural gas over a programmable duration of time. Micro-miniature fabrication of the gas chromatograph imparts important advantages to the system 110, including small size, modular design, low power consumption, fast BTU analysis times, and low consumption of consumable carrier and reference gases.
    Type: Grant
    Filed: November 18, 1999
    Date of Patent: May 14, 2002
    Assignee: Eagle Research Corporation
    Inventor: James N. Butch
  • Patent number: 6357277
    Abstract: The invention concerns a method for the realignment of peaks in gas chromatographic analyses after the replacement of the used capillary column with a nominally equal one, wherein a K coefficient characteristic of the column is preventively calculated by flowing carrier gas in the column under stabilized conditions of pressure and flow rate and of the column temperature, said K coefficient being stored in a memory of the gas chromatographic system. Said K coefficient is used to correlate at least two of the above mentioned parameters in subsequent analyses, obtaining an automatic realignment of peaks. The invention also concerns the analytical equipment to perform the method, and the capillary gas chromatographic column characterized as reported above.
    Type: Grant
    Filed: September 24, 1999
    Date of Patent: March 19, 2002
    Assignee: Thermoquest Italia S.p.A.
    Inventors: Fausto Pigozzo, Pier Albino Colombo, Paolo Magni, Sorin Trestianu
  • Patent number: 6338824
    Abstract: An ultratrace detector system for hand-held gas chromatography having high sensitivity, for example, to emissions generated during production of weapons, biological compounds, drugs, etc. The detector system is insensitive to water, air, helium, argon, oxygen, and CO2. The detector system is basically composed of a hand-held capillary gas chromatography (GC), an insulated heated redox-chamber, a detection chamber, and a vapor trap. For example, the detector system may use gas phase redox reactions and spectral absorption of mercury vapor. The gas chromatograph initially separates compounds that percolate through a bed of heated mercuric oxide (HgO) in a silica—or other metal—aerogel material which acts as an insulator.
    Type: Grant
    Filed: June 8, 1999
    Date of Patent: January 15, 2002
    Assignee: The Regents of the University of California
    Inventors: Brian D. Andresen, Fred S. Miller
  • Patent number: 6314374
    Abstract: A method of properly correcting a base line. A concept of flexibility of a base line is introduced as an input index and a gravitation is presumed between the base line and signal data which is measured, thereby constructing a method of correcting the base line which changes gentler than a change in signal with respect to time in a peak area and which is sensitive to an area where a value of the signal data is small. A base line like a natural and smooth curve which isn't easily influenced by a local change in signal such as noise or the like can be set by an input of the flexibility.
    Type: Grant
    Filed: May 1, 2000
    Date of Patent: November 6, 2001
    Assignees: Hitachi, Ltd., Hitachi Instruments Engineering Co., Ltd.
    Inventors: Masahito Ito, Kisaburo Deguchi, Yoshiaki Seki
  • Patent number: 6257047
    Abstract: The invention concerns a method and an apparatus for the direct injection of large volumes (>3 &mgr;l) of samples into the column in a gas chromatography analysis apparatus comprising an oven, a gas chromatography column lodged in the oven, a means for the direct transfer into the column of the sample and a source of carrier gas upstream the column, as well as a detector downstream the column. According to the invention two or more of the parameters: nature of the solvent injection rate flow-rate and/or pressure of the carrier gas temperature at least of an initial length of the column during the injection are correlated and/or controlled to achieve a control of the length of the zone wetted by the sample during its introduction.
    Type: Grant
    Filed: May 20, 1999
    Date of Patent: July 10, 2001
    Assignee: Themoquest Italia S.p.A.
    Inventors: Konrad Grob, Fausto Munari, Pier Albino Colombo, Paolo Magni
  • Patent number: 6225132
    Abstract: A method for detecting an analyte of interest present in a mixture at an ultralow concentration includes selecting a radioactive derivatizing agent comprising a multiphoton-emitting radioisotope moiety and a moiety reactive with the analyte of interest, the radioisotope moeity being bound to the derivatizing agent by a bond that is stable under the conditions employed in the other steps of the method, derivatizing the analyte of interest with the derivatizing agent, separating the analyte of interest from other components of the mixture by chromatography, and detecting the analyte of interest using multiphoton detection. The derivatizing step may be performed before or after fractionation. A radiophore for multiphoton emission enhanced chromatography has a first moeity bound to a multiphoton-emitting radioisotope, and a second moiety that is reactive with a functional group of an analyte of interest.
    Type: Grant
    Filed: December 10, 1998
    Date of Patent: May 1, 2001
    Assignee: BioTraces, Inc.
    Inventors: Andrzej K. Drukier, Roman Bielski
  • Patent number: 6210465
    Abstract: A method for identifying components within a known type of sample through pattern recognition between an array of recognition coefficients generated from the attributes and stable relationships of a plurality of peaks within a chromatogram of a sample to be analyzed and a similar array of recognition coefficients generated from the attributes and stable relationships of a plurality of peaks from a set of one or more historical chromatograms of the known type of sample. The group of attributes include, but are not limited to: retention time, peak shape including symmetry, width and duration, peak size including area and height, and algorithmic measures of peak type.
    Type: Grant
    Filed: March 17, 1999
    Date of Patent: April 3, 2001
    Assignee: Agilent Technologies, Inc.
    Inventor: Lee H. Altmayer