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  • Publication number: 20180351550
    Abstract: The device has an input element, which can be used for resetting the device. The input element has at least one first photodiode arranged in series to at least one second photodiode. A voltage is applied over the photodiodes. When the user blocks light to only the second photodiode, the voltage at the interconnection between the photodiodes changes, which can be used to trigger the input element. The input element has low power consumption and high reliability.
    Type: Application
    Filed: November 13, 2015
    Publication date: December 6, 2018
    Applicant: BIOVOTION AG
    Inventor: Thomas DEGEN
  • Patent number: 10659042
    Abstract: The device has an input element, which can be used for resetting the device. The input element has at least one first photodiode arranged in series to at least one second photodiode. A voltage is applied over the photodiodes. When the user blocks light to only the second photodiode, the voltage at the interconnection between the photodiodes changes, which can be used to trigger the input element. The input element has low power consumption and high reliability.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: May 19, 2020
    Assignee: Biovotion AG
    Inventor: Thomas Degen
  • Patent number: 9155505
    Abstract: A sensor device comprises a sensor (1) to be held against the wearer's skin. The sensor (1) is arranged on one side of a housing (2), and the housing is connected to a band (5) for mounting it to a body part, such as an arm or leg. Various stopper devices (10, 14, 20) are arranged on the side of the housing (2) and the band (5) that face the skin. The stopper devices improve static friction, thereby holding the housing (2) in place.
    Type: Grant
    Filed: February 5, 2010
    Date of Patent: October 13, 2015
    Assignee: BIOVOTION AG
    Inventors: Andreas Caduff, Hans-Joachim Krebs, Gianlucca Stalder, Mark Stuart Talary
  • Patent number: 9247905
    Abstract: A method and device for determining the glucose level in living tissue are based on measuring the response of the tissue an electric field as well as temperature measurements. In order to improve accuracy, it has been found that measurements in at least three frequency ranges between 1 kHz and 200 kHz, 0.2 MHz an 100 MHz as well as above 1 GHz should be combined since the response of the tissue in these different frequency ranges is ruled by differing mechanisms.
    Type: Grant
    Filed: April 17, 2009
    Date of Patent: February 2, 2016
    Assignee: BIOVOTION AG
    Inventors: Andreas Caduff, Mark Stuart Talary, Martin Müller, Oscar De Feo
  • Patent number: 9549695
    Abstract: A parameter affecting the absorptivity or the concentration of blood in tissue is measured using a semiconductor light source (7) and a light detector (8). The semiconductor light source (7) is operated at several operating conditions, at which it has different temperatures and therefore different emission spectra. In particular, the operating conditions correspond to different time intervals after switching the light source (7) on, while the light source (7) has not yet reached thermal equilibrium. This allows to perform a spectroscopic measurement using one light source only, which increases accuracy and reduces device cost.
    Type: Grant
    Filed: February 26, 2010
    Date of Patent: January 24, 2017
    Assignee: BIOVOTION AG
    Inventors: Andreas Caduff, Hans-Joachim Krebs, Mark Stuart Talary, Pavel Zakharov
  • Patent number: 9713447
    Abstract: The apparatus for the non-invasive glucose detection comprises an electrical detection device (2) for measuring the response of the tissue or blood to an electric field at low frequencies below 1 MHz and at high frequencies above 10 MHz. The former is primarily dominated by skin hydration and sweat, while the latter contains contributions from the current glucose level. Combining the two signals allows an increased degree of accuracy. The apparatus further comprises a force or acceleration sensor (4, 5), which allows to detect the pressure of the apparatus against the skin and/or quick movements. Further sensor modules, such as a temperature sensor (6) or alternative perfusion sensor (7), improve the accuracy of the measured result.
    Type: Grant
    Filed: November 10, 2005
    Date of Patent: July 25, 2017
    Assignee: BIOVOTION AG
    Inventors: Andreas Caduff, Mark Stuart Talary, Francois Dewarrat, Daniel Huber, Gianluca Stalder
  • Patent number: 9179856
    Abstract: A device is described for measuring a parameter of living tissue, in particular a glucose level, which parameter affects a response of said tissue to an electric field. The device comprises a substrate (2), which carries a ground electrode (10) as well as a plurality of signal electrodes (12a, 12b, 13a-13c, 14). The gaps (15) between the ground electrode and the signal electrodes are filled with a solid filler material (16) in order to provide an even surface. Optical reflection detectors (23a, 23b, 23c) can also be located in these gaps in order to avoid field distortions and obtain a compact design. The backside of substrate (2) carries electronic high-frequency components for improving signal quality.
    Type: Grant
    Filed: April 17, 2009
    Date of Patent: November 10, 2015
    Assignee: BIOVOTION AG
    Inventors: Andreas Caduff, Mark Stuart Talary, Hans-Joachim Krebs, Alexander Megej, Francois Dewarrat
  • Publication number: 20150190063
    Abstract: Embodiments of the present invention comprise systems and methods for noninvasion measurements of physiological properties of tissues. The system comprises a light emitter, an optical detector, a mechanical sensor and a processor. The light emitter is capable of emitting light of at least two different wavelengths and comprises at least one light source. The processor is capable of evaluating physiological properties of the tissues from measurements of the optical and the mechanical sensor. More precisely, the processor is capable of evaluating physiological properties of venous blood by using data measured by the mechanical sensor and the optical detector. For example, the oxygenation of venous blood can be measured. Furthermore, the systems can optionally comprise a light emitter which emits three wavelengths and/or the light emitter and the optical detector are arranged in reflection geometry and are located at a distance of at most 10 mm from each other.
    Type: Application
    Filed: October 19, 2011
    Publication date: July 9, 2015
    Applicant: BIOVOTION AG
    Inventors: Pavel Zakharov, Mark Talary, Andreas Caduff
  • Patent number: 9526431
    Abstract: Embodiments of the present invention comprise systems and methods for noninvasion measurements of physiological properties of tissues. The system comprises a light emitter, an optical detector, a mechanical sensor and a processor. The light emitter is capable of emitting light of at least two different wavelengths and comprises at least one light source. The processor is capable of evaluating physiological properties of the tissues from measurements of the optical and the mechanical sensor. More precisely, the processor is capable of evaluating physiological properties of venous blood by using data measured by the mechanical sensor and the optical detector. For example, the oxygenation of venous blood can be measured. Furthermore, the systems can optionally comprise a light emitter which emits three wavelengths and/or the light emitter and the optical detector are arranged in reflection geometry and are located at a distance of at most 10 mm from each other.
    Type: Grant
    Filed: October 19, 2011
    Date of Patent: December 27, 2016
    Assignee: BIOVOTION AG
    Inventors: Pavel Zakharov, Mark Talary, Andreas Caduff
  • Patent number: 8197406
    Abstract: A device for measuring the glucose level in living tissue has electrodes (5, 6) for being brought into contact with the specimen and a voltage-controlled oscillator (31) as a signal source for generating an AC voltage in a given frequency range. The AC voltage is applied to the electrodes (5, 6). A voltage over the electrodes is fed to a processing circuitry (37, 38), which converts it to the glucose level using calibration data. The voltage-controlled oscillator (31) has a symmetric design with adjustable gain for generating signals in a large frequency range with low distortions at a low supply voltage. The processing circuit comprises a simple rectifier network with software-based correction. The electrodes (5, 6) are of asymmetric design and optimized for biological compatibility.
    Type: Grant
    Filed: February 10, 2004
    Date of Patent: June 12, 2012
    Assignee: Biovotion AG
    Inventors: Andreas Caduff, Stephan Buschor, Pascal Truffer, Etienne Hirt, Gianluca Stalder
  • Patent number: 8200307
    Abstract: A device for measuring a glucose level or some other parameter of living tissue that affects the dielectric properties of the tissue is disclosed. The device comprises an electrode arrangement (5) having a plurality of electrodes (5-i). The signal from a signal source (31) can be applied to the electrode arrangement via a switching assembly (39). The switching assembly (39) is designed to selectively connect a first and a second pattern of the electrodes (5-i) to the signal source, thereby generating a first and a second electrical field with different spatial distribution in the tissue. By using a differential method which relies on measuring the impedance of the electrode arrangement (5) for each field and on suitable subtraction of the measured results, surface effects can be reduced and the focus of the measurement can be offset to a point deeper inside the tissue.
    Type: Grant
    Filed: June 7, 2004
    Date of Patent: June 12, 2012
    Assignee: Biovotion AG
    Inventors: Andreas Caduff, Pascal Truffer, Yaroslav Ryabov, Yuri Feldman, Alexander Puzenko
  • Patent number: D901692
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: November 10, 2020
    Assignee: BIOVOTION AG
    Inventors: Veikko Rihu, Jussi Juva, Antti Eskeli, Atte Peltola, Niki Kurki, Andreas Caduff
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