Search Patents
  • Publication number: 20130133242
    Abstract: A group of tertiary amine azides are useful as hypergolic fuels for hypergolic bipropellant mixtures. The fuels provide higher density impulses than monomethyl hydrazine (MMH) but are less toxic and have lower vapor pressures that MMH. In addition, the fuels have shorter ignition delay times than dimethylaminoethylazide (DMAZ) and other potential reduced toxicity replacements for MMH.
    Type: Application
    Filed: January 23, 2013
    Publication date: May 30, 2013
    Applicant: CFD RESEARCH CORPORATION
    Inventor: CFD Research Corporation
  • Publication number: 20130101991
    Abstract: An apparatus for assaying a tumor drug delivery vehicle and or drug can include an idealized microvascular network (IMN) of one or more interconnected idealized flow channels in fluid communication through a porous wall with a tissue space (e.g., idealized tissue space) containing animal cells and means for quantifying drug delivery through the IMN to the animal cells.
    Type: Application
    Filed: December 14, 2012
    Publication date: April 25, 2013
    Applicant: CFD Research Corporation
    Inventor: CFD Research Corporation
  • Publication number: 20130149735
    Abstract: Methods of assaying the leukocyte adhesion cascade (LAC) and monitoring leukocyte rolling, adhesion, and/or migration can be implemented with an apparatus that includes an idealized microvascular network (IMN) of one or more interconnected idealized flow channels in fluid communication through a porous wall with a tissue space (e.g., idealized tissue space). The methods of assaying the LAC can be implemented with means for quantifying modulation of the leukocyte adhesion cascade. Methods of assaying the LAC can be implemented with the device and one or more active agents to monitor leukocyte rolling, adhesion, and/or migration in the presence of absence of the active agent. Migration can be through the idealized flow channels, through the porous wall, and/or into the tissue space.
    Type: Application
    Filed: January 16, 2013
    Publication date: June 13, 2013
    Applicant: CFD RESEARCH CORPORATION
    Inventor: CFD Research Corporation
  • Publication number: 20110014368
    Abstract: The growth temperature of carbon nanotubes on a catalyst distributed on a substrate is reduced by controlling graphene layer formation on the catalyst and catalyst deactivation by catalytic oxidation.
    Type: Application
    Filed: July 14, 2009
    Publication date: January 20, 2011
    Applicant: CFD RESEARCH CORPORATION
    Inventor: Aleksey V. Vasenkov
  • Publication number: 20100319822
    Abstract: A method and apparatus for gelling liquid propane and other liquefied gasses includes a temperature controlled churn mixer, vacuum pump, liquefied gas transfer tank, and means for measuring amount of material entering the mixer. The apparatus and method are particularly useful for the production of high quality rocket fuels and propellants.
    Type: Application
    Filed: September 2, 2010
    Publication date: December 23, 2010
    Applicant: CFD RESEARCH CORPORATION
    Inventors: Adam Elliott, Roberto DiSalvo, Phillip Shepherd, Ryan Kosier
  • Patent number: 8417465
    Abstract: An apparatus and method for assaying blood-brain barrier properties for drug and drug delivery vehicle screening comprising of a microfluidic apparatus with gaps separating lumen and tissue space enabling formation of tight junctions similar to in vivo conditions using endothelial cells and brain cells.
    Type: Grant
    Filed: March 17, 2010
    Date of Patent: April 9, 2013
    Assignee: CFD Research Corporation
    Inventors: Balabhaskar Prabhakarpandian, Kapil Pant, Shivshankar Sundaram, Ketan Harendrakumar Bhatt
  • Publication number: 20090120843
    Abstract: A filtration apparatus is disclosed for the removal of metals from jet fuel at high flow rates and limited pressure drops. The filter comprises a monolayer of immobilized chelating agent on packed silica gel. The filtration apparatus is particularly useful for the removal of copper from jet fuel.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 14, 2009
    Applicant: CFD Research Corporation
    Inventors: Ashok Gidwani, Debasis Sengupta, Vernon Cole, Stelu Deaconu, Jianjun Wei
  • Publication number: 20100099136
    Abstract: An apparatus and method for assaying a tumor drug delivery vehicle comprises a synthetic microvascular network of interconnected flow channels in fluid communication through a porous wall with a tissue space containing animal cells and means for quantifying drug delivery from the microvascular network to the animal cells.
    Type: Application
    Filed: December 28, 2009
    Publication date: April 22, 2010
    Applicant: CFD RESEARCH CORPORATION
    Inventors: Balabhaskar Prabhakarpandian, Kapil Pant, Shivshankar Sundaram
  • Patent number: 8355876
    Abstract: An apparatus and method for assaying a tumor drug delivery vehicle comprises a synthetic microvascular network of interconnected flow channels in fluid communication through a porous wall with a tissue space containing animal cells and means for quantifying drug delivery from the microvascular network to the animal cells.
    Type: Grant
    Filed: December 28, 2009
    Date of Patent: January 15, 2013
    Assignee: CFD Research Corporation
    Inventors: Balabhaskar Prabhakarpandian, Kapil Pant, Shivshankar Sundaram
  • Publication number: 20080202655
    Abstract: Disclosed is a group of tertiary amine azides useful as hypergolic fuels for hypergolic bipropellant mixtures. The fuels provide higher density impulses than monomethyl hydrazine (MMH) but are less toxic and have lower vapor pressures that MMH. In addition, the fuels have shorter ignition delay times than dimethylaminoethylazide (DMAZ) and other potential reduced toxicity replacements for MMH.
    Type: Application
    Filed: February 27, 2007
    Publication date: August 28, 2008
    Applicant: CFD Research Corporation
    Inventor: Debasis Sengupta
  • Publication number: 20120168046
    Abstract: A group of tertiary amine azides are useful as hypergolic fuels for hypergolic bipropellant mixtures. The fuels provide higher density impulses than monomethyl hydrazine (MMH) but are less toxic and have lower vapor pressures that MMH. In addition, the fuels have shorter ignition delay times than dimethylaminoethylazide (DMAZ) and other potential reduced toxicity replacements for MMH.
    Type: Application
    Filed: May 18, 2010
    Publication date: July 5, 2012
    Applicant: CFD RESEARCH CORPORATION
    Inventor: Debasis Sengupta
  • Publication number: 20110104658
    Abstract: An apparatus and method for assaying blood-brain barrier properties for drug and drug delivery vehicle screening comprising of a microfluidic apparatus with gaps separating lumen and tissue space enabling formation of tight junctions similar to in vivo conditions using endothelial cells and brain cells.
    Type: Application
    Filed: March 17, 2010
    Publication date: May 5, 2011
    Applicant: CFD Research Corporation
    Inventors: Balabhaskar Prabhakarpandian, Kapil Pant, Shivshankar Sundaram, Ketan Bhatt
  • Publication number: 20100226847
    Abstract: The present invention is a method comprising a direct chirality-selective nucleation and synthesis of single-walled carbon nanotubes from carbon-containing gases using catalytic nanoparticles of uniform size heated by ultra-short laser pulses of selected frequency to temperatures sufficient for carbon nanotube nucleation and synthesis.
    Type: Application
    Filed: March 5, 2009
    Publication date: September 9, 2010
    Applicant: CFD RESEARCH CORPORATION
    Inventor: Aleksey V. Vasenkov
  • Publication number: 20090311445
    Abstract: A catalytic chemical vapor deposition method and apparatus for synthesizing carbon nanotubes and/or carbon nanofibers (CNTs) on a substrate involves selectively heating a catalyst for CNT synthesis on or near the surface of the substrate. Selective heating of the catalyst is achieved using inductive heating from a radio frequency source. Selective heating of the catalyst prevents heating of the substrate and enables the synthesis of CNTs on temperature sensitive substrates.
    Type: Application
    Filed: August 5, 2009
    Publication date: December 17, 2009
    Applicant: CFD RESEARCH CORPORATION
    Inventor: Aleksey V. Vasenkov
  • Patent number: 8685186
    Abstract: A group of tertiary amine azides are useful as hypergolic fuels for hypergolic bipropellant mixtures. The fuels provide higher density impulses than monomethyl hydrazine (MMH) but are less toxic and have lower vapor pressures that MMH. In addition, the fuels have shorter ignition delay times than dimethylaminoethylazide (DMAZ) and other potential reduced toxicity replacements for MMH.
    Type: Grant
    Filed: January 23, 2013
    Date of Patent: April 1, 2014
    Assignee: CFD Research Corporation
    Inventor: Debasis Sengupta
  • Publication number: 20100227312
    Abstract: A method for characterizing particle adhesion in microfluidic bifurcations and junctions comprises at least one idealized bifurcation or junction. Multiple bifurcations and/or junctions can be combined on a single microfluidic chip to create microfluidic networks configured for assays specifically to characterize particle interactions at junctions or to screen particles for desired interactions with microfluidic bifurcations and/or junctions.
    Type: Application
    Filed: March 6, 2009
    Publication date: September 9, 2010
    Applicant: CFD RESEARCH CORPORATION
    Inventors: Kapil Pant, Balabhaskar Prabhakarpandian, Shivshankar Sundaram, Angela Irene Rea-Ramsey
  • Publication number: 20090292480
    Abstract: A synthetic microfluidic microvasculature network and associated methods mimic the structure, fluid flow characteristics, and physiological behavior of physiological microvasculature networks. Computational methods for simulating flow and particle adherence in synthetic and physiological microvascular systems and methods for determining parameters influencing particle adhesion and drug delivery are described with applications in the optimization of drug delivery and microvascular treatments and in describing disease mechanisms that affect the microvasculature.
    Type: Application
    Filed: April 22, 2009
    Publication date: November 26, 2009
    Applicant: CFD RESEARCH CORPORATION
    Inventors: Balabhaskar Prabhakarpandian, Shivshankar Sundaram, Kapil Pant
  • Patent number: 8382922
    Abstract: A group of tertiary amine azides are useful as hypergolic fuels for hypergolic bipropellant mixtures. The fuels provide higher density impulses than monomethyl hydrazine (MMH) but are less toxic and have lower vapor pressures that MMH. In addition, the fuels have shorter ignition delay times than dimethylaminoethylazide (DMAZ) and other potential reduced toxicity replacements for MMH.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: February 26, 2013
    Assignee: CFD Research Corporation
    Inventor: Debasis Sengupta
  • Publication number: 20080182027
    Abstract: The present invention is a catalytic chemical vapor deposition method and apparatus for synthesizing carbon nanotubes and/or carbon nanofibers (CNTs) on a substrate by selectively heating a catalyst for CNT synthesis on or near the surface of the substrate. Selective heating of the catalyst is achieved using an exothermic oxidation reaction on the surface of the catalyst, inductive heating from a radio frequency source, or both. Selective heating of the catalyst prevents heating of the substrate and enables the synthesis of CNTs on temperature sensitive substrates.
    Type: Application
    Filed: January 30, 2007
    Publication date: July 31, 2008
    Applicant: CFD RESEARCH CORPORATION
    Inventor: Aleksey V. Vasenkov
  • Publication number: 20100112667
    Abstract: A microfluidic cartridge for isolating biological molecules having a capture chamber containing functionalized solid supports maintained in a fluidized state provides reduced pressure drops and bubble formation during microfluidic extraction. The cartridge may include an electric field lysis chamber and/or a chemical lysis chamber. The electric-field lysis chamber may comprise an electrically insulating structure arranged between two opposing planar electrodes.
    Type: Application
    Filed: November 3, 2008
    Publication date: May 6, 2010
    Applicant: CFD RESEARCH CORPORATION
    Inventors: Shivshankar Sundaram, Balabhaskar Prabhakarpandian, Kapil Pant, Yi Wang
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