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  • Isoxazole and isothiazole compounds for the treatment of neurodegenerative disorders
    Publication number: 20040242666
    Abstract: The present invention relates to compounds of the Formula 1
    Type: Application
    Filed: May 12, 2004
    Publication date: December 2, 2004
    Applicants: Pfizer, Inc., Pfizer Products, Inc.
    Inventor: Yuhpyng Liang Chen
  • CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF
    Publication number: 20130129753
    Abstract: The present invention is directed to cytotoxic pentapeptides, to antibody drug conjugates thereof, and to methods for using the same to treat cancer.
    Type: Application
    Filed: November 7, 2012
    Publication date: May 23, 2013
    Applicant: PFIZER INC.
    Inventor: PFIZER INC.
  • RESORCINOL DERIVATIVES
    Publication number: 20070122367
    Abstract: The present invention relates to certain resorcinol derivatives and their use as skin lightening agents.
    Type: Application
    Filed: November 21, 2006
    Publication date: May 31, 2007
    Applicants: PFIZER INC., PFIZER PRODUCTS INC.
    Inventors: Stuart Bradley, Eric Collington, Matthew Fyfe, Martin Procter, Colin Sambrook Smith
  • Treatment of Pulmonary Hypertension
    Publication number: 20130203767
    Abstract: This invention relates to the use of certain cyclic guanosine 3?,5?-monophosphate phosphodiesterase type five (cGMP PDE5) inhibitors, including in particular the compound sildenafil, for the treatment of pulmonary hypertension.
    Type: Application
    Filed: March 14, 2013
    Publication date: August 8, 2013
    Applicant: Pfizer Inc.
    Inventor: Pfizer Inc.
  • Treatment of Male Sexual Dysfunction
    Publication number: 20130121923
    Abstract: A composition comprising a selective oxytocin antagonist for use in the treatment and/or prevention of a male ejaculatory disorder; which selective oxytocin antagonist is optionally admixed with a pharmaceutically acceptable carrier, diluent or excipient.
    Type: Application
    Filed: January 16, 2013
    Publication date: May 16, 2013
    Applicant: PFIZER INC.
    Inventor: PFIZER INC.
  • Methods of treatment and formulations of cephalosporin
    Patent number: 7378408
    Abstract: Formulations containing an antibacterial alkali metal salt of a cephalosporin compound and methods of treating bacterial infections in dogs and cats.
    Type: Grant
    Filed: November 12, 2002
    Date of Patent: May 27, 2008
    Assignees: Pfizer Inc., Pfizer Products Inc.
    Inventors: Roger N. Kimball, Renuka D. Reddy, Evgenyi Y. Shalaev
  • Process for the preparation of non-steroidal glucocorticoid receptor modulators
    Patent number: 6727392
    Abstract: A process for preparing a compound of the formula useful as a non-steroidal glucocorticoid receptor modulator.
    Type: Grant
    Filed: October 15, 2002
    Date of Patent: April 27, 2004
    Assignees: Pfizer Inc., Pfizer Products Inc.
    Inventors: Jerry A. Murry, Timothy D. White
  • 4,4-Biarylpiperidine derivatives
    Publication number: 20040138220
    Abstract: The present invention relates to compounds of the formula I, 1
    Type: Application
    Filed: December 23, 2003
    Publication date: July 15, 2004
    Applicants: Pfizer, Inc., Pfizer Products, Inc.
    Inventor: Spiros Liras
  • Neospora vaccine
    Patent number: 6787146
    Abstract: The present invention provides an homogenate prepared from cells of Neospora, and vaccines against neosporosis prepared therefrom which are useful in the prevention of clinical disease and abortion in mammals.
    Type: Grant
    Filed: November 9, 2001
    Date of Patent: September 7, 2004
    Assignees: Pfizer Inc., Pfizer Products Inc.
    Inventors: David A. Brake, Manuel Campos
  • ANTHELMINTIC COMBINATION
    Publication number: 20100197624
    Abstract: A method is provided for the treatment of parasitic infestations in mammals, comprising the step of simultaneously or sequentially administering to the mammal effective amounts of (a) 2-desoxoparaherquamide; and (b) abamectin. Also provided is an anthelmintic composition comprising 2-desoxoparaherquamide and abamectin.
    Type: Application
    Filed: June 16, 2008
    Publication date: August 5, 2010
    Applicants: PFIZER INC., PFIZER PRODUCTS INC.
    Inventors: Timothy G. Geary, Peter Rolfe
  • N1-Pyrazolospiroketone Acetyl-CoA Carboxylase Inhibitors
    Publication number: 20130030181
    Abstract: The invention provides a compound of Formula (I) or a pharmaceutically acceptable salt of the compound, wherein R1, R2, R3 and R4 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of an acetyl-CoA carboxylase enzyme(s) in an animal.
    Type: Application
    Filed: October 4, 2012
    Publication date: January 31, 2013
    Applicant: PFIZER INC.
    Inventor: Pfizer Inc.
  • ETHER DERIVATIVES USEFUL AS INHIBITORS OF PDE4 ISOZYMES
    Publication number: 20070161681
    Abstract: Compounds useful as inhibitors of PDE4 in the treatment of diseases regulated by the activation and degranulation of eosinophils, especially asthma, chronic bronchitis, and chronic obstructive pulmonary disease, of the formula: wherein the substituents are as defined in the specification.
    Type: Application
    Filed: January 30, 2007
    Publication date: July 12, 2007
    Applicants: PFIZER INC., PFIZER PRODUCTS INC.
    Inventors: Anthony Marfat, Robert Chambers, Thomas Magee
  • Cannabinoid receptor ligands and uses thereof
    Patent number: 7247628
    Abstract: Compounds of Formula (I) that act as cannabinoid receptor ligands and their uses in the treatment diseases, conditions and/or disorders herein.
    Type: Grant
    Filed: November 4, 2003
    Date of Patent: July 24, 2007
    Assignees: Pfizer, Inc., Pfizer Products, Inc.
    Inventors: Robert L. Dow, Marlys Hammond
  • Process for preparing alkanesulfonyl pyridines
    Patent number: 6590103
    Abstract: A process for preparing alkanesulfonyl pyridines of the formula 1: is disclosed, wherein R1 is as defined herein. The compounds of formula 1 are useful in the preparation of pyridyl-substituted pyrazoles used in the treatment and alleviation of inflammation and other inflammation associated disorders.
    Type: Grant
    Filed: September 27, 2002
    Date of Patent: July 8, 2003
    Assignees: Pfizer, Inc., Pfizer Products, Inc.
    Inventors: Jolanta Nowakowski, Dieter Haag
  • 4,4-biarylpiperidine derivatives
    Patent number: 6720336
    Abstract: The present invention relates to compounds of the formula I, wherein Z1, Z2, R1, R2 and R3 are defined as in the specification, pharmaceutical compositions containing such compounds the use of such compounds to treat neurological and gastrointestinal disorders.
    Type: Grant
    Filed: July 10, 2001
    Date of Patent: April 13, 2004
    Assignees: Pfizer, Inc., Pfizer Products, Inc.
    Inventor: Spiros Liras
  • DIOXA-BICYCLO[3.2.1]OCTANE-2,3,4-TRIOL DERIVATIVES
    Publication number: 20130225487
    Abstract: Compounds of Formula (A) and (B) are described herein and the uses thereof for the treatment of diseases, conditions and/or disorders mediated by sodium-glucose transporter inhibitors (in particular, SGLT2 inhibitors).
    Type: Application
    Filed: March 12, 2013
    Publication date: August 29, 2013
    Applicant: Pfizer Inc.
    Inventor: Pfizer Inc.
  • Substituted Heteroaryls
    Publication number: 20130165452
    Abstract: The present invention provides Formula (1A) compounds that act as glucokinase activators; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by glucokinase. X, Y, Z, R1, R2, R3, and R4 are as described herein.
    Type: Application
    Filed: February 22, 2013
    Publication date: June 27, 2013
    Applicant: PFIZER INC.
    Inventor: Pfizer Inc.
  • Resorcinol derivatives
    Patent number: 7173052
    Abstract: The present invention relates to certain resorcinol derivatives and their use as skin lightening agents.
    Type: Grant
    Filed: December 2, 2004
    Date of Patent: February 6, 2007
    Assignees: Pfizer Inc., Pfizer Products Inc.
    Inventors: Stuart E. Bradley, Eric W. Collington, Matthew C. Fyfe, Martin J. Procter, Colin P. Sambrook Smith
  • METHODS OF VACCINE ADMINISTRATION
    Publication number: 20100028379
    Abstract: This invention relates to a method of treating a dog for canine diseases comprising administering to the dog therapeutically effective amounts of a vaccine, wherein the vaccine comprises viral antigens, a bacterin, or both, and wherein the vaccine is administered subcutaneously or orally according to the schedules provided herein.
    Type: Application
    Filed: November 23, 2007
    Publication date: February 4, 2010
    Applicants: PFIZER, INC, PFIZER PRODUCTS INC.
    Inventors: Cassius M. Tucker, John David Haworth
  • Compounds for the treatment of neurodegenerative disorders
    Publication number: 20050043372
    Abstract: The present invention relates to compounds of the Formula wherein R3, R5, R7, U, X, Y and Z are as defined. Compounds of the Formula I have activity inhibiting production of A?-peptide. This invention also relates to pharmaceutical compositions and methods of treating diseases, for example, neurodegenerative diseases, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.
    Type: Application
    Filed: August 20, 2004
    Publication date: February 24, 2005
    Applicants: Pfizer, Inc., Pfizer Products Inc.
    Inventor: Yuhpyng Chen
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