Abstract: An infusion pump includes a core member and a bladder member which are substantially spheroidal at one end and cylindrical at the other end. The core member is inserted inside the bladder member and a ring member engages the cylindrical ends of the core and bladder member to sealingly secure the bladder to the core. A tubular hose is included and is coupled with an infusion port of the core member. When fluid is injected into the pump, it causes the bladder member to inflate substantially symmetrically and spherically around an axial axis of the core member. Upon deflating the bladder member, the fluid is ejected out of the pump at a constant flow rate.

Abstract: A medical liquid filling system and associated methods are provided, the system comprising a disposable and a drive system. The disposable includes a tubular member and a piston slidably disposed within the tubular member for retraction and advancement within at least a first portion of the tubular member. The disposable may include a seal member for sealing the first portion of the tubular member and may be interconnected to the piston for co-movement therewith. The drive system may include a piston drive member selectively interconnectable to the piston for driven advancement and retraction of the piston within the tubular member. The drive system may be interconnected to a controller, which may be operable to automate or semi-automate various filling operations. A user interface may be interconnected to the controller for providing input of various system operation parameters, which may be communicated to the controller to facilitate automated or semi-automated operation of the filling system.

Abstract: A medical liquid filling system and associated methods are provided, the system comprising a disposable and a drive system. The disposable includes a tubular member and a piston slidably disposed within the tubular member for retraction and advancement within at least a first portion of the tubular member. The disposable may include a seal member for sealing the first portion of the tubular member and may be interconnected to the piston for co-movement therewith. The drive system may include a piston drive member selectively interconnectable to the piston for driven advancement and retraction of the piston within the tubular member. The drive system may be interconnected to a controller, which may be operable to automate or semi-automate various filling operations. A user interface may be interconnected to the controller for providing input of various system operation parameters, which may be communicated to the controller to facilitate automated or semi-automated operation of the filing system.

Abstract: A medical liquid filling system and associated methods are provided, the system comprising a disposable and a drive system. The disposable includes a tubular member and a piston slidably disposed within the tubular member for retraction and advancement within at least a first portion of the tubular member. The disposable may include a seal member for sealing the first portion of the tubular member and may be interconnected to the piston for co-movement therewith. The drive system may include a piston drive member selectively interconnectable to the piston for driven advancement and retraction of the piston within the tubular member. The drive system may be interconnected to a controller, which may be operable to automate or semi-automate various filling operations. A user interface may be interconnected to the controller for providing input of various system operation parameters, which may be communicated to the controller to facilitate automated or semi-automated operation of the filling system.

Abstract: An apparatus and method for transferring a chosen quantity of medication from a vial to an intravenous infuser container under sterile conditions is described. The present invention further facilitates dissolving solid medications contained in the vial or diluting concentrated medications contained in the vial, and transferring the resulting solutions to the infuser container.

Abstract: The present invention relates to devices and methods for the filling syringes. One medical apparatus in accordance with the present invention include a body member for releasably holding syringe barrels and an actuator apparatus slidably mounted on the body member to engage syringe plungers to cause the syringe plunger to be retracted. A fluid delivery apparatus is releasably mounted to the body member. The fluid delivery apparatus has an inlet port and a plurality of outlet ports. The inlet port is in fluid communication with each of the plurality of outlet ports. One method for filling a plurality of syringes in accordance with the present invention includes the steps of mounting a plurality a syringes to a syringe holding member and connecting a fluid delivery apparatus to the syringe holding member to mate with each of the tips of the syringe barrels.

Abstract: In a liquid handling system including a liquid handling substrate having a plurality of channels for conducting a liquid sample in said substrate, where the channels terminate in a plurality of exit ports in an outer surface of the substrate for transfer of a quantity of the liquid sample. The handling system also includes a liquid storage and dispensing substrate having a plurality of separable cartridges corresponding to the channels, with each cartridge terminating at a microelectro mechanical system (MEMS) comprising a laminate of glass, silicon and a piezoelectric substance. The handling system further includes a liquid detecting system comprising a light emitting diode and a photo-detector, where each channel includes a reservoir in communication with a corresponding cartridge creating an interface therebetween.

Abstract: A direct dual filling device for sealing agents capable of transferring a material from a commercially available material container to a material applicator. The filling device of the present invention comprises a hood defining at least one receiving aperture, an applicator interface in communication with the hood and having at least one filling port formed thereon, at least one transfer conduit in communication with the at least one filling port, at least one withdrawal cannula located within the receiving aperture and in communication with the at least one transfer conduit, and a container support device capable of receiving and supporting at least one material container in an upright tilted position within the receiving aperture. The hood may include at least one engaging surface and at least one displacement recess.

Abstract: A filter vent fitting for a drum which allows for the passage of hydrogen gas but precludes the passage of radioactive particulates, the fitting having evacuation/pressurization conduits which allow the drum to be evacuated or pressurized, and cryogenic/sapling conduits which allow the temperature of the drum to be reduced and samples drawn from the interior which are not filtered. Preferably a cap member is provided with a pressure balancing bore which is active during the evacuation and pressurization steps.

Abstract: A filling system of a packaging machine is set forth that reduces the mixing of product and air during the filling of the container with a flowable material such as low fat milk. The fill pipe of the filling system has an elliptical cross-section which provides for a reduced velocity of the flowable material entering the container while allowing for an increased production time of the packaging machine. The fill system is especially adopted to fill containers having a rectangular cross-section. Connected to the fill pipe is a nozzle with flaps designed to substantially conform and engage with the sidewalls of a container. When the flaps are urged to an open position, the mixing of air and product is inhibited as the flowable material is dispensed into the container through the nozzle and as a moving mechanism is operated to relatively move the container and nozzle from a first to a second position. The fill pipe has an elongate body, an inlet end and an outlet end.

Abstract: A filling system of a packaging machine is set forth that reduces the mixing of product and air during the filling of a container with a product. The filling system is designed to fill a container having a cross section defined by a plurality of sidewalls, an interior bottom engaging the sidewalls, and an open top. The system includes a fill pump for pumping a liquid product and a fill pipe, the fill pipe having an inlet receiving liquid under pressure from the fill pump and an outlet overlying the container. A nozzle is disposed over the outlet end of the fill pipe. The nozzle comprises a collar for connecting the nozzle to the outlet end of the fill pipe and a plurality of flaps formed from a flexible material extending from the collar. The plurality of flaps are preferably biased to a closed position, such as under their own resilience. The nozzle seals the outlet end of the fill pipe when in this closed position.

Abstract: A filling system for filling a container is set forth. The container to be filled has a bottom portion and a plurality of sidewalls defining a container cross-section. The filling system comprises a fill pipe having a product inlet and a product outlet, a valve rod disposed in the fill pipe, a flexible outlet extension, and an umbrella-shaped sealing member having a bottom portion. The valve rod and the sealing member are movable between a first position in which the sealing member engages and seals the product outlet and a second position in which the sealing member is disengaged from the product outlet. The bottom portion of the sealing member is preferably shaped to conform to the interior bottom portion of the container. The flexible outlet extension extends from the product outlet and is dimensioned to engage and conform to the sidewalls of the container during filling thereby to inhibit mixing of product and air during the filling cycle.

Abstract: A fluid delivery apparatus which includes a fluid delivery assembly and a unique fill assembly that can be used to controllably fill the fluid reservoir of the fluid delivery assembly in the field. The fill assembly includes a fluid containing vial assembly mounted within a unique adapter assembly which functions to conveniently mate the vial assembly with several different types of fluid delivery assemblies of the character that embody self-contained stored energy means.

Abstract: A drug reconstitution and administration system includes a container for a concentrated drug or other medicament, a syringe assembly which can be pre-filled with a liquid diluent, and a mixing adapter assembly which facilitates mixing of the medicament with the liquid diluent. The adapter assembly includes inner and outer concentrically arranged, relatively movable sleeves, which together define an expandable mixing chamber within the adapter assembly. The container and pre-filled syringe are respectively fitted to the adapter assembly, with the contents of the container and the contents of the syringe transferred into the internal mixing chamber. A diluted drug mixture is formed in the mixing chamber, and the mixture is transferred into the syringe assembly for subsequent patient administration.

Abstract: An injection pen apparatus (30) for medicament injection including a medicament cartridge assembly (31) formed to receive and contain a medicament therein. A holding sleeve (34) is provided which is dimensioned to receive the medicament cartridge assembly (31) therein which mates with a solution transfer device (35) including an axially movable displacement rod (36). The injection pen apparatus (30) further includes a coupling mechanism (37) removably coupling the solution transfer device (35) to both a plunger (32) slidably movable in the cartridge (33) and to the holding sleeve (34). A sleeve mounting assembly (40) of the coupling mechanism (37) removably mounts the coupling mechanism to the holding sleeve (34).

Abstract: A rotating blade is passed beneath an extruder nozzle and employed to cut tails of viscous materials which have been extruded.

Abstract: Method and apparatus for handling a liquid sample such as a blood sample, which has been processed to obtain phase separation of the sample's components. The apparatus includes a cup for containing a quantity of the separated fluid phase of the sample, a suction cylinder and probe usable with the cup for extracting the fluid phase and an associated container for holding the remainder of the sample. Preferably, the cup has a specific configuration which provides for nesting within the top portion of the container and concurrently provides for tight sliding engagement with the inside surface of the suction cylinder to extract the fluid phase by a piston-like cooperation. An optional thin sleeve may be inserted over the bottom portion of the cup, prior to nesting, to prevent contamination of the outside walls thereof.