Patents Represented by Attorney A. A. Orlinger
  • Patent number: 4261253
    Abstract: A pouch-packet having walls with V-shaped or Y-shaped separation-enhancing deformations formed therein, and the method and apparatus for making the same are disclosed herein.
    Type: Grant
    Filed: October 26, 1977
    Date of Patent: April 14, 1981
    Assignee: Drug Concentrates, Inc.
    Inventor: George B. Smith, II
  • Patent number: 4239516
    Abstract: Gas-vapor treating and filter mats composed of glass fibers intermixed with micro-bits of any of an expanded thermoplastic styrene-polymer or expanded thermoplastic lower polyolefin or flexible foam polyurethane and a suitable organic bonding agent, which mat may contain any of fibers of a fiber-forming terephthalate polyester, activated carbon, and gas-vapor adsorbent crystalline zeolite molecular sieve particles.
    Type: Grant
    Filed: March 8, 1979
    Date of Patent: December 16, 1980
    Inventor: Max Klein
  • Patent number: 4235772
    Abstract: Described are novel growth promoting peptides of the general formula:P-Cys-Q-Cys-RwhereP is hydrogen, or Phe-Asn-Val-Asp-Lys-Lys-;Q is selected from -Gln-, or -Ser-Tyr-Tyr-Gln-Ser-Asn-, or -Tyr-Thr-Ala-Glu-; andR is selected from -Thr, -Lys-Pro-Gln-Val-Thr, or -Asp-Glu-Leu;and of the corresponding reduced linear form of any of the foregoing, as well as the corresponding pharmaceutically acceptable acid addition salts of any of the foregoing. The corresponding intermediates or intermediary compounds with amino and/or carboxyl groups protected are also covered.
    Type: Grant
    Filed: June 20, 1979
    Date of Patent: November 25, 1980
    Assignee: AB Kabi
    Inventors: Ronny-Hugo L. Lundin, Gertrud E. Westin-Sjodahl, Karin H. L. Bergendal, Linda M. Fryklund
  • Patent number: 4227946
    Abstract: An acid aqueous coating composition and concentrate of chromic acid and chromium phosphate derived from phosphoric acid resulting from the oxidation of hypophosphorous acid in reacting with the chromic acid. The chromic acid is present in a stoichiometrically equivalent amount from about one percent to about one hundred percent over that needed to oxidize hypophosphorous acid to phosphoric acid. The composition may also contain a non-foaming wetting agent and particulate silica.
    Type: Grant
    Filed: February 9, 1979
    Date of Patent: October 14, 1980
    Assignee: Oakite Products, Inc.
    Inventor: Stanley C. Williamson
  • Patent number: 4212782
    Abstract: Disclosed are solid, readily water-soluble addition polymers of acid addition salts of methacrylic acid and a 2-mono(lower)alkylaminoethyl methacrylate, whose lower alkyl group has up to 6 carbons and is straight or branched chain or cyclic. These polymers are insoluble in pentane, hexane and butane below their boiling points, and their aqueous solutions show amphoteric activity. These polymers result from polymerizing the starting monomeric acid addition salt of methacrylic acid and a 2-mono(lower)alkylaminoethyl methacrylate in the ratio of from about one mol to about 1.5 mols of one of them per mol of the other. Also disclosed is the method of producing these addition polymers by heating the starting acid addition salt under pressure in a low boiling aliphatic solvent at a temperature above its boiling point, from which after lowering the temperature the resulting addition polymer readily is separated as a light weight finely divided product.
    Type: Grant
    Filed: May 8, 1978
    Date of Patent: July 15, 1980
    Assignee: Normac, Inc.
    Inventor: Max Klein
  • Patent number: 4207378
    Abstract: Involved are (I) expanded, thermoplastic, non-brittle as expanded polymers selected from a styrene-polymer and a polyolefin from polyethylene to poly-methylpentene, said expanded polymer being in form of micro-bits which (a) are from about 40 to about 325 microns long and from about 20 to about 325 microns wide, (b) are substantially completely to entirely completely free (i) of intact cells of expanded polymer bit-pieces from which they were produced and of (ii) any uniformity in outline of individual micro-bit particles, and (c) in density are from about 85 percent of, to about substantially the same as, the specific unexpanded polymer from which there was provided the aforesaid expanded polymer, and (II) a method of preparing these micro-bits by impelling a mixture of them in water in a confined comminuting zone through a circular path by repeated impact by a plurality of impact surfaces spaced axially and radially at apart from one another and rotated about the circular path's axis from about 4700 to abou
    Type: Grant
    Filed: September 15, 1977
    Date of Patent: June 10, 1980
    Inventor: Max Klein
  • Patent number: 4204468
    Abstract: An embossing press designed to enable embossing, for example, a sender's name and address in customary reading location respectively separately selectively on letter writing paper sheets and on envelop flaps is provided with unique die plate carrying means enabling easy removal of the opposed die holders each with its individual die plate and replacement of them in horizontally reversed position. Each of the die plates is mounted in the terminal slot in its respective spring leaf or arm of a double-armed spring die holders carrier, both arms of which are joined at their inner end integrally to a yoke, by means of which the spring die holders carrier is attached rigidly firmly yet removably (when needed) to the supporting base of the press.
    Type: Grant
    Filed: July 20, 1978
    Date of Patent: May 27, 1980
    Assignee: M & R Seal Press Co., Inc.
    Inventor: Paul H. Harrison
  • Patent number: 4200679
    Abstract: A polyurethane structure prepared by the comminution of a flexible polyurethane foam in the presence of a compatible protective cooling fluid.
    Type: Grant
    Filed: September 15, 1977
    Date of Patent: April 29, 1980
    Inventor: Max Klein
  • Patent number: 4184251
    Abstract: An instrument for processing artificial teeth and the like, which is utilizable for collecting precious metallic powder shavings produced during the processing of the teeth, and which comprises a handy bowl-like collector and a collector plate for supplementally collecting the powders which have not been caught by the handy bowl-like collector.
    Type: Grant
    Filed: February 6, 1978
    Date of Patent: January 22, 1980
    Inventor: Tamotsu Kuboki
  • Patent number: 4178246
    Abstract: Method and apparatus of concentrating solids from a suspension by feeding material in a liquid medium to a first zone that includes a vertically oriented foraminous filter basket supported by circular bands which are connected to an open frame basket supporting cage. Rotary impeller arms significantly spaced from the basket inclined from the vertical and located about midway of the lower half of the basket impart a circular laminar movement to the material. A vertical cylindrical tank surrounds the basket. Filtrate is collected in the annular region between the basket and tank. Discharge outlets with rate of discharge controls extend outwardly and downwardly from the bottom of the separator apparatus. Operation can be batch or continuous with level of filtrate in the tank being maintained on a par with the level of the feed in the basket.
    Type: Grant
    Filed: May 31, 1977
    Date of Patent: December 11, 1979
    Inventor: Max Klein
  • Patent number: 4168146
    Abstract: A test strip for carrying out immunoassays. The test strip is a bibulous carrier to which antibodies are bound. The immunoassay is carried out by wetting the test strip with the aqueous solution containing a suspected antigen. The test strip is then contacted with an aqueous solution containing labeled antibodies.
    Type: Grant
    Filed: January 15, 1976
    Date of Patent: September 18, 1979
    Assignee: AB Kabi
    Inventors: Anders O. Grubb, Ulla C. Glad
  • Patent number: 4168300
    Abstract: Hepatitis virus is removed from a biological material contaminated with the virus by contact with a preparation. The preparation may be agarose gel or beaded polyacrylamide plastic coupled with a variety of hydrophobic ligands.
    Type: Grant
    Filed: July 6, 1976
    Date of Patent: September 18, 1979
    Assignee: AB Kabi
    Inventors: Lars-Olov Andersson, Hakan G. Borg, Gudrun M. Einarsson
  • Patent number: 4138287
    Abstract: Hepatitis B virus (detectable as its surface antigen HB.sub.s Ag) is produced in a purification preferably suitable for use in preparing a hepatitis vaccine, by contacting a crude biological starting material containing hepatitis B virus with a water-insoluble cross-linked sulfated polysaccharide gel matrix adsorbing agent to adsorb the hepatitis B virus thereon and then desorbing that virus therefrom by treating that hepatitis B virus carrying adsorbent with a desorbing agent.
    Type: Grant
    Filed: March 15, 1977
    Date of Patent: February 6, 1979
    Assignee: AB Kabi
    Inventors: Lars-Olov Andersson, Gudrun M. Einarsson, Lennart P. Kaplan
  • Patent number: 4119774
    Abstract: Crude clinically used heparin preparations having a low specific activity, for example, about 130 heparin units per milligram are purified by contacting such liquid crude heparin preparations with a gel matrix complexed with (i.e. having linked to it) antithrombin or inter-alpha-trypsin inhibitor as a heparin-binding plasma protein, and then desorbing or eluting the heparin from the antithrombin or inter-alpha-trypsin inhibitor complexed gel matrix as with an applicable buffer, removing any salt in the solution with the heparin by gel filtration and then drying the heparin as by lyophilization.
    Type: Grant
    Filed: March 2, 1977
    Date of Patent: October 10, 1978
    Assignee: AB Kabi
    Inventors: Lars-Olov Andersson, Erik Yngve Holmer
  • Patent number: 4089957
    Abstract: Disclosed is (1) a method of resisting as well as suppressing recurrent venous thrombosis in a human susceptible to or having said thrombosis, which method comprises administering to said human a recurrent venous thrombosis-combatting effective dose of a pharmaceutical composition comprising a pharmaceutically acceptable acid addition salt of moroxydine, such as of an inorganic acid as hydrochloric or sulphuric, or an aliphatic carboxylic acid such as any of acetic, ascorbic, citric, fumaric, gluconic, glycolic, lactic, levulinic, maleic, tartaric, salicylic or nicotinic acids, and (2) pharmaceutical preparations containing such acid addition salts for the indicated use.
    Type: Grant
    Filed: June 6, 1977
    Date of Patent: May 16, 1978
    Assignee: AB Kabi
    Inventor: Nils Ake Jonsson
  • Patent number: 4066408
    Abstract: An analytical test, color change reagent preparation comprising peroxidase, an oxygen-oxidoreductase specific to a particular substance to be tested and a chromogen-reactive-indicator formula selected from (a) those having the general formula ##STR1## wherein X is the divalent carbonyloxy or sulfonyloxy group, W is hydrogen or another cation compatible with the aforesaid other ingredients of said reagent preparation, the subscript n is 0 or 1, and (i) when X is the carbonyloxy group, A is a divalent alkylene chain with from 2 to about 7 carbons, and (ii) when X is the sulfonyloxy group, n is 0 when A is the divalent alkylene chain of from 2 to about 7 carbons, and n is 1 when A is straight chain trimethylene or tetramethylene, and (b) the acid addition salts of said disubstituted benzidine derivative, compatible with the aforesaid ingredients of the chromogen-reactive-indicator, when X is the carbonyloxy group.
    Type: Grant
    Filed: February 9, 1977
    Date of Patent: January 3, 1978
    Assignee: AB Kabi
    Inventors: Nils Ake Jonsson, Ferenc Merenyi, Lars-Erik Westlund
  • Patent number: 4058512
    Abstract: Novel synthetic peptides of the general formula ##STR1## and the corresponding reduced, linear form. The cyclic form of the peptide is produced by oxidation of the corresponding linear compound thereby providing the divalent dithio group --S--S-- joining the beta carbon of each of the cysteine moieties. In the above formula X is serine (SER) or lysine (Lys), and Y is OH or Thr-Glu-Gly-Phe. The obtained synthetic peptides, in either form, are useful in promoting growth of cells of mammalian tissues.
    Type: Grant
    Filed: April 28, 1975
    Date of Patent: November 15, 1977
    Assignee: AB Kabi
    Inventors: Hans Sievertsson, Ronny Hugo Loritz Lundin, Gertrud Elisabeth Westin Sjodahl
  • Patent number: 4054557
    Abstract: The application discloses (A) a growth-promoting polypeptide having molecular weight from about 5,000 to about 7,000 chromatographic mobility under electrophoresis from about 0.25 to about 0.37 relative to lysine at pH 5 and from about 0.17 to about 0.43 relative to aspartic acid at pH 7.5, terminal amino acid at its amino end being asparagine or aspartic acid, and respective amounts of aspartic acid, threonine, serine, glutamic acid, proline, glycine, alanine, valine, leucine, tyrosine, phenylalanine, lysine, arginine, trypophan, and cysteine or carboxymethyl cysteine, and also a couple of instances also methionine, isoleucine and histidine; and (B) the derivation of the polypeptides from blood serum or plasma or a plasma fraction by combined steps of (a) homogenizing the starting material in water, (b) admixing a solution of hydrochloric acid in ethanol thereby splitting the polypeptide from its carrier proteins and precipitating them, (c) adjusting the pH to 8.
    Type: Grant
    Filed: May 15, 1974
    Date of Patent: October 18, 1977
    Assignee: AB Kabi
    Inventors: Hans Uno Sievertsson, Linda Fryklund, Knut Oivind Uthne
  • Patent number: 4050897
    Abstract: An apparatus that comprises (a) a fluid-tightly closeable materials-treating or reaction chamber with at least its body portion substantially completely enclosed by a temperature-control fluid chamber provided by its being surrounded by a temperature-control fluid jacket, (b) means to rotate the jacketed chamber end over end about an axis substantially normally transverse to its central axis, (c) divider-baffling means dividing its temperature-control fluid chamber into a plurality of, such as four, substantially similar and independent control-fluid compartments or quadrants, (d) temperature-control fluid ingress means which enable feeding temperature-control fluid into such quadrant while the reactor is rotating, (e) means in each compartment or quadrant to affect the flow of fluids through it to provide substantially uniform overall heat transfer from each of them; and (f) fluid egress means to enable discharging heat-control fluid from these compartments during the rotation.
    Type: Grant
    Filed: July 27, 1976
    Date of Patent: September 27, 1977
    Assignee: Normac, Inc.
    Inventor: Max Klein
  • Patent number: RE30149
    Abstract: Disclosed and claimed is the preparation of the 4-aminomethyl-cyclohexane carboxylic acid isomer assaying at least about 90% antifibrinolytically active material from specific para-disubstituted cyclohexane starting material. For example, in 4-aminomethyl-cyclohexane methanol such as its isomer melting at 118.degree. C. in a series of steps its methanol group is converted to carboxyl. More specifically its amino group is blocked by reaction with benzoyl halide and the methanol group then oxidized to carboxyl, and the benzoyl group removed to yield the end product isomer.1-4-dimethyl-cyclohexane dicarboxylate melting at 69.degree.-71.degree. C., another such cyclohexane starting material, is hydrolyzed to its mono-ester which with thionyl halide is converted to the halide of the half-ester, which latter reacted with ammonia gives the corresponding ester amide.
    Type: Grant
    Filed: January 30, 1979
    Date of Patent: November 13, 1979
    Assignee: AB Kabi
    Inventors: Bengt O. Melander, Gunnar Hanshoff, Bengt R. G. Granstrand, Berit M. Olsson