Abstract: Gene expression profiles produced in response to lunasin exposure, wherein such gene expression profiles correlate with anti-neoplastic activity, methods for using such expression profiles for screening potential anti-neoplastic agents, and methods for treatment and monitoring of a subject having a neoplastic disease.

Abstract: The present invention encompasses a device for changing the temperature of the kidney during laparoscopic surgery or during organ transportation or transplantation.

Abstract: The present invention provides methods for purifying insoluble bone gelatin and uses for insoluble bone gelatin. The process for isolating insoluble bone gelatin from bone tissue includes grinding the bone tissue into bone powder; washing the bone powder with saline; demineralizing the bone tissue; contacting the bone powder with a neutral salt; and contacting the bone powder with a stabilizer. The present invention also discloses an insoluble bone gelatin including about 10 percent growth factor. Insoluble bone gelatin is useful, for example, in preparing impaction bone grafts.

Abstract: The Integrated Body Conditioning (IBC) exercise system is a method of exercising employing three defining elements: integration of aerobic, resistance, and Range of Motion exercises performed at a properly elevated heart rate with exercise intensity and duration adjusted in view of biofeedback data.

Abstract: The present invention features devices and methods for delivery of drug to an internal organ surface by delivery of drug directly to the surface of the organ such that the drug traverses the organ surface and enters the organ tissue. The device is in the form of an implantable drug delivery patch comprising a first layer, which is generally substantially drug-impermeable. When the first layer is placed on an outer surface of an organ, a drug reservoir is defined by the first layer and the organ surface.

Abstract: Methods and apparatus used for securing the end of a drug-delivery catheter at the round window niche of the inner ear; specifically an apparatus employing a miniature threaded screw pump to inflate a balloon allowing a catheter to be secured within the round window niche of the inner ear.

Abstract: A method for safely removing a contaminant from a substrate surface without the need for any precoating of the substrate. Because the resultant molecular decomposition of the contaminant occurs relatively faster than heat transfer to the underlying substrate, substantially no substrate heating results. The light source is preferably a xenon flash lamp operated with a pulse repetition rate of between about 0.1 pulses/second and 12 pulses/second, an energy pulse duration of about 400 microseconds to about 800 microseconds, and a peak energy per pulse exceeding about 3,750 joule. Ultraviolet elements of the spectrum produced by the flash lamp are reduced or eliminated by the use of filters or reflectors that absorb or otherwise eliminate ultraviolet light. The substrate to be decontaminated may be the exposed surface of a living animal or plant or may be protective clothing or a vehicle contaminated with chemical or biological agents.