Patents Represented by Attorney Albert H. Graddis

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  • Aporphine derivatives
    Patent number: 4120964
    Abstract: The present invention is concerned with new and novel 4-hydroxyaporphine derivatives and with the preparation thereof.
    Type: Grant
    Filed: May 25, 1977
    Date of Patent: October 17, 1978
    Assignee: Warner-Lambert Company
    Inventors: Johannes Hartenstein, Gerhard Satzinger
  • Bronchodilating piperidinoethyl benzopyranopyridinones
    Patent number: 4117140
    Abstract: Disclosed are novel substituted benzopyranopyridines which are active as bronchodilators.
    Type: Grant
    Filed: June 30, 1977
    Date of Patent: September 26, 1978
    Inventors: Richard E. Brown, Chester Puchalski, John Shavel, Jr.
  • 1,2-Benzoxathiin-2,2,-dioxides
    Patent number: 4116961
    Abstract: Disclosed are substituted 1,2-benzoxathin-2,2-dioxide, and methods for their manufacture. These compounds show antiinflammatory activity.
    Type: Grant
    Filed: February 24, 1977
    Date of Patent: September 26, 1978
    Assignee: Warner-Lambert Company
    Inventors: Charles F. Schwender, Brooks R. Sunday
  • Indolobenzoxazepines as CNS depressants
    Patent number: 4117129
    Abstract: This invention relates to substituted indolobenzoxazepines which act as central nervous system depressants and as such are useful as tranquillizers.
    Type: Grant
    Filed: September 8, 1977
    Date of Patent: September 26, 1978
    Assignee: Warner-Lambert Company
    Inventor: Richard E. Brown
  • 4,5-Dihydro-4,5-dioxo-1H-1-benzopyrano (2,3-B)-pyridine-3-carboxylic acids, salts and esters
    Patent number: 4117134
    Abstract: This invention relates to compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, lower alkyl, halogen, hydroxy or lower alkoxy; R.sub.2 is hydrogen or lower alkyl; R.sub.3 is hydrogen or lower alkyl; and the pharmaceutically acceptable, non-toxic salts thereof. The compounds of the invention are active in the prevention of allergic and asthmatic reactions in mammals.
    Type: Grant
    Filed: June 13, 1978
    Date of Patent: September 26, 1978
    Assignee: Warner-Lambert Company
    Inventors: David T. Connor, Maximilian VON Strandtmann
  • 15-Cyclobutyl-prostaglandins
    Patent number: 4117119
    Abstract: Prostaglandin analogues of the formula: ##STR1## wherein A represents a grouping of the formula: ##STR2## X represents trans-vinylene or ethylene and Y represents cis-vinylene or ethylene, R represents hydrogen or alkyl of 1 through 12 carbon atoms, R.sup.1, R.sup.2 and R.sup.3 represent hydrogen, or alkyl of 1 through 12 carbon atoms or an aryl group, with the proviso that at least one of the symbols R.sup.1, R.sup.2 and R.sup.3 represents an alkyl or aryl group, are new compounds possessing useful pharmacological properties; they are especially useful for the treatment of gastric ulceration.
    Type: Grant
    Filed: May 6, 1977
    Date of Patent: September 26, 1978
    Assignee: Ono Pharmaceutical Company
    Inventors: Masayasu Kurono, Hisao Nakai, Takashi Muryobayashi
  • 3-(1H-Tetrazol-5-yl)chromones
    Patent number: 4116971
    Abstract: There is described 3-(1H-tetrazol-5-yl)chromones having the following structural formula: ##STR1## in which R is lower alkoxy having 1 to 3 carbon atoms, aryl such as phenyl, halogen or trihalo lower alkyl. These compounds exhibit anti-allergic properties and are indicated in the treatment of allergic conditions such as hay fever and asthma.
    Type: Grant
    Filed: August 15, 1977
    Date of Patent: September 26, 1978
    Assignee: Warner-Lambert Company
    Inventors: Max von Strandtmann, Marvin P. Cohen, Sylvester Klutchko, John Shavel, Jr.
  • Method of inhibiting gastric acid secretions with 2-(4-pyrimidinyl)thioacetamides
    Patent number: 4117131
    Abstract: 2-(4-Pyrimidinyl)thioacetamides are disclosed that have been found useful in the treatment of gastric hyperacidity.
    Type: Grant
    Filed: September 12, 1977
    Date of Patent: September 26, 1978
    Assignee: Warner-Lambert Company
    Inventors: Charles F. Schwender, Russell E. Pike
  • Immunoassay device
    Patent number: 4116638
    Abstract: An assembly for use as a solid phase support for immunoassay procedures.
    Type: Grant
    Filed: March 3, 1977
    Date of Patent: September 26, 1978
    Assignee: Warner-Lambert Company
    Inventor: Michael B. Kenoff
  • 2-[(N-2-pyridylcarbamoyl)methyl]saccharin
    Patent number: 4116964
    Abstract: A novel process for preparing 4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides is disclosed. The process involves the base catalyzed rearrangement of a saccharinacetamide of structure I to give II, ##STR1## wherein R.sup.1 is hydrogen or lower alkyl and R.sup.2 is lower alkyl, aryl or a heterocyclic ring selected from the group consisting of pyridyl, substituted-pyridyl, and thiazolyl. Compounds of the formula II have useful anti-inflammatory properties. In addition, they can be used as intermediates in the preparation of known anti-inflammatory agents.
    Type: Grant
    Filed: August 16, 1977
    Date of Patent: September 26, 1978
    Assignee: Warner-Lambert Company
    Inventors: Harold Zinnes, Neil A. Lindo, John Shavel, Jr.
  • 1-Benzoxepino[4,3-c]pyridines
    Patent number: 4116966
    Abstract: The present invention is concerned with 11-oxo-1-benzoxepino[4,3-c]pyridines of Formula I: ##STR1## wherein R.sub.1 and R.sub.2 may be hydrogen, lower alkyl, cyano, carboxamido, carboxy, ethoxycarbonyl or tetrazolyl and R.sub.3 may be hydrogen, lower alkyl, halogen, hydroxy or lower alkoxy.These compounds are indicated in the management of allergic conditions such as bronchial asthma, hay fever and the like.
    Type: Grant
    Filed: November 21, 1977
    Date of Patent: September 26, 1978
    Assignee: Warner-Lambert Company
    Inventors: Sylvester Klutchko, Max VON Strandtmann
  • 6,7-Dimethoxy-2-(4-thiomorpholinyl)-4-quinazolinamine and related sulfoxide and sulfone
    Patent number: 4115565
    Abstract: Disclosed are a series of quinazoline derivatives which have activity as hypotensive agents.
    Type: Grant
    Filed: October 25, 1977
    Date of Patent: September 19, 1978
    Assignee: Warner-Lambert Company
    Inventors: Lawrence D. Wise, Glenn C. Morrison
  • Candy dispenser
    Patent number: D249333
    Type: Grant
    Filed: June 7, 1976
    Date of Patent: September 12, 1978
    Assignee: Warner-Lambert Company
    Inventor: Walter Stern
  • Candy dispenser
    Patent number: D249469
    Type: Grant
    Filed: June 7, 1976
    Date of Patent: September 19, 1978
    Assignee: Warner-Lambert Company
    Inventor: Frank Russert
  • Candy dispenser
    Patent number: D249471
    Type: Grant
    Filed: June 7, 1976
    Date of Patent: September 19, 1978
    Assignee: Warner-Lambert Company
    Inventor: Walter Stern
  • Candy dispenser
    Patent number: D249868
    Type: Grant
    Filed: June 7, 1976
    Date of Patent: October 10, 1978
    Assignee: Warner-Lambert Company
    Inventor: Frank Russert
  • Candy dispenser
    Patent number: D249929
    Type: Grant
    Filed: June 7, 1976
    Date of Patent: October 17, 1978
    Assignee: Warner-Lambert Company
    Inventor: Frank Russert
  • Candy dispenser
    Patent number: D249932
    Type: Grant
    Filed: June 7, 1976
    Date of Patent: October 17, 1978
    Assignee: Warner-Lambert Company
    Inventor: Frank Russert
  • Dispensing container for pharmaceutical diluents
    Patent number: D249958
    Type: Grant
    Filed: January 10, 1977
    Date of Patent: October 17, 1978
    Assignee: Warner-Lambert Company
    Inventor: Eugene J. Meierhoefer
  • Razor
    Patent number: D249968
    Type: Grant
    Filed: August 23, 1976
    Date of Patent: October 17, 1978
    Assignee: Warner-Lambert Company
    Inventor: Ernest F. Kiraly