Patents Represented by Attorney Andrews Kurth LLP
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Patent number: 8283377Abstract: Provided is a method for inhibiting blood vessel stenosis in a subject, comprising administrating to the subject an effective amount of an active ingredient selected from a group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound, a pharmaceutically acceptable ester of the compound, and combinations thereof. Also provided is a method for inhibiting blood vessel stenosis in a subject, comprising administration to the subject an effective amount of an Angelicae Sinensis extract comprising the compound of formula (I).Type: GrantFiled: May 20, 2011Date of Patent: October 9, 2012Assignee: China Medical UniversityInventors: Shinn-Zong Lin, Horng-Jyh Harn, Tzyy-Wen Chiou, Li-Fu Chang
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Patent number: 8273388Abstract: An extract of Polygonum multiflorum Thunb. ex Murray var. hypoleucum (Ohwi) or of Polygonum hypoleucum (Ohwi) for improving metabolic syndrome is prepared by the following method: (a) providing fresh or dry Polygonum multiflorum Thunb. ex Murray var. hypoleucum (Ohwi) or Polygonum hypoleucum (Ohwi) in partial or whole plant; (b) extracting the partial or whole plant by a solvent to obtain a crude extract; (c) condensing and drying the crude extract to obtain an extract product; and (d) collecting the extract product. The present invention also relates to a pharmaceutical and a food composition having the above extract for improving the metabolic syndromes. The extract of the present invention can be easily prepared and is demonstrated to modulate the levels of both blood glucose and blood lipid, to inhibit the activities of glycolytic enzymes and acetyl-CoA carboxylase, and to stimulate acyl-CoA oxidase. The extract of the present invention is capable of improving metabolic syndromes.Type: GrantFiled: April 29, 2011Date of Patent: September 25, 2012Assignee: Food Industry Research & Development InstituteInventors: Chi-Hua Chen, Shiow-Wen Chen, Yuarn-Yee Chang, Wen-Kia Liu
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Patent number: 8264814Abstract: A downhole release tool for use in conjunction with multiple select-fire perforating guns and a method for electronically actuating the release tool using either positive or negative control voltage. In a preferred embodiment, the release tool employs operating circuitry that allows actuation of the release tool by either a positive or a negative voltage at an absolute magnitude greater than the absolute magnitude of positive or negative voltages used to arm or fire the perforating guns.Type: GrantFiled: September 23, 2009Date of Patent: September 11, 2012Assignee: Casedhole Solutions, Inc.Inventors: Lyle G. Love, Michael W. Dobrinski, Frank L. Lezu, Jr., John R. Harris, Brian S. Buffington, Sanford E. Stark
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Patent number: 8261966Abstract: A receptacle for secure mail and parcel receipt and storage. The receptacle includes a top which provides a roof for the receptacle, a base, and a housing connected to the top and the base. The housing includes an upper compartment into which mail is first placed, a lower compartment into which mail is deposited from the upper compartment, a front door, located on a front of the receptacle, which is opened to provide access to the upper compartment and through which mail is placed into the upper compartment, a trap door, operatively connected to the front door, in the upper compartment, and an access door that includes a lock. The trap door rests in an open position when the front door is closed, allowing communication between the upper and lower compartments. The trap door is moved to a closed position by the opening of the front door, thereby preventing access to the lower compartment from the upper compartment.Type: GrantFiled: July 8, 2011Date of Patent: September 11, 2012Assignee: Postal Hawk CorporationInventors: Bobbie Cox, Jeffrey Kalman, Craig Saunders, Lindsey Tufts, Jr., Chuck Hosier, Paul Stephens
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Patent number: 8263396Abstract: A method for the production of a replication-deficient recombinant virus vector is disclosed. The replication-deficient recombinant virus vector has a recombinant virus genome with one or more defective viral genes. The method comprises infecting a host cell with a carrier virus having a carrier virus genome encoding one or more trans factors or variants thereof, incubating the infected host cell for a desired period of time, and isolating the replication-deficient recombinant virus vector. The carrier virus is a cytoplasmic virus that retains the carrier virus genome in the cytoplasm of the host cell. The host cell contains the recombinant viral genome and retains the recombinant viral genome in a nucleus of the host cell. Also disclosed is a carrier virus for the production of a replication-deficient recombinant virus vector.Type: GrantFiled: April 1, 2010Date of Patent: September 11, 2012Inventor: Weidong Xiao
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Patent number: 8262656Abstract: An external fixation device for the setting and corrective treatment of bone fractures is disclosed. The device comprises a splint member having a first and a second axially slidable and mutually fastenable base portions for adjusting the length of the splint member and a plurality of bone pins. Each of the base portions of the splint member includes mountings for the bone pins to traverse the site of the bone fracture in a multi-angle and multi-planar pin configuration, so as to permit direct fixation of the fracture and provide a significant degree of stability.Type: GrantFiled: February 13, 2009Date of Patent: September 11, 2012Assignee: A.M. Surgical, Inc.Inventors: Ather Mirza, Romi Mirza
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Patent number: 8258027Abstract: An embodiment of a method is disclosed to integrate silicon oxide nitride oxide silicon (SONOS) non-volatile memory (NVM) into a conventional complementary metal oxide semiconductor (CMOS) semiconductor foundry process flow. An embodiment of the method only adds a few additional steps to a standard CMOS foundry process flow and makes minor changes to the rest of the baseline CMOS foundry process flow to form a new process module that includes both CMOS devices and an embedded SONOS NVM.Type: GrantFiled: November 8, 2010Date of Patent: September 4, 2012Assignee: Northrop Grumman Systems CorporationInventors: Joseph Terence Smith, Dennis A. Adams, Patrick Bruckner Shea
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Patent number: 8256434Abstract: The present invention concerns an at least partially transparent cigarette filter tipping film comprising a biodegradable substrate, and softener in an amount of less than 25% by weight of the biodegradable substrate, and a cigarette filter comprising a filtration material encased in a cylinder of the said tipping film.Type: GrantFiled: August 11, 2010Date of Patent: September 4, 2012Assignee: Innovia Films LimitedInventors: Paul Watters, Colin Marshall
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Patent number: 8251003Abstract: An offshore structure having a vertically symmetric hull, an upper vertical wall, an upper inwardly-tapered wall disposed below the upper vertical wall, a lower outwardly-tapered wall disposed below the upper sloped wall, and a lower vertical wall disposed below the lower sloped wall. The upper and lower sloped walls produce significant heave damping in response to heavy wave action. A heavy slurry of hematite and water ballast is added to the lower and outermost portions of the hull to lower the center of gravity below the center of buoyancy. The offshore structure provides one or more movable hawser connections that allow a tanker vessel to moor directly to the offshore structure during offloading rather than mooring to a separate buoy at some distance from the offshore storage structure. The movable hawser connection includes an arcuate rail with a movable trolley that provides a hawser connection point that allows vessel weathervaning.Type: GrantFiled: October 28, 2010Date of Patent: August 28, 2012Assignee: SSP Technologies, Inc.Inventor: Nicolaas J. Vandenworm
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Patent number: 8251610Abstract: The present invention provides an apparatus for creating an outer surface effect of a structure wherein at least one wall of the structure defines a support surface, the apparatus comprising means defining a covering surface which overlies the support surface but is movable therefrom, so that a quantity of material to create the outer surface effect can be positioned between the support surface and the covering surface, and wherein the covering surface is in the form of a panel.Type: GrantFiled: December 11, 2009Date of Patent: August 28, 2012Assignee: Hesco Bastion LimitedInventor: James Heselden
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Patent number: 8252722Abstract: The present invention is directed to methods for inhibiting the growth of disease organisms, particularly fungi and bacteria, on plant tissues. The present invention is also directed to methods for inhibiting the infestation of plants by insects and larva, particularly sucking and chewing insects. These methods are achieved by applying an auxin or a plant growth regulator (PGR) which will effect the level of auxin in the plant tissue to the seeds or tubers of the plant prior to planting or to the roots, foliage, flowers or fruit of the plant after planting.Type: GrantFiled: October 2, 2003Date of Patent: August 28, 2012Assignee: Stoller Enterprises, Inc.Inventor: Jerry H. Stoller
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Patent number: 8245892Abstract: An ornamental belt buckle/cup-holder combination having a front plate pivotably connected at its lower end to the lower end of a back plate. The back side of the buckle includes brackets and a hook for securing a belt. The front side of the buckle includes ornamentation. The front and back plates are held in parallel abutment with magnets. A loop is pivotably mounted to the top of the back plate and is captured between the front plate and the back plate when they in parallel abutment. The loop is urged into a upward perpendicular position relative to the back plate with a spring. When the front plate is folded downward perpendicular to the back plate, it forms a lower horizontal surface for supporting the weight of a beverage container. The loop is then urged by the spring into an upper horizontal position for receiving and laterally supporting the beverage container.Type: GrantFiled: October 9, 2008Date of Patent: August 21, 2012Assignee: Beer Clothing Company, LLCInventor: Jay P. Kriner
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Patent number: 8246691Abstract: A bioabsorable stent is disclosed. The stent is made of a bioabsorable material and has an elongated body having a proximate end, a distal end, and at least one open channel formed on the exterior surface of the elongated body to provide fluid communication between the proximal end and the distal end. Also disclosed is a bioabsorable stent having an elongated center rod having a proximate end and a distal end and a plurality of leaflets extending outward from the center rod and forming channels between two neighboring leaflets to provide fluid communication between the proximal end and the distal end.Type: GrantFiled: April 2, 2009Date of Patent: August 21, 2012Inventor: Eric Mangiardi
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Patent number: 8245564Abstract: A system for remote detection of a chemical is disclosed. The system includes a sample collection module that collects a sample and produces a sample vapor at a first location; a sample delivery module that delivers the sample vapor from the first location to a second location; a sample storage and concentration module that collects the sample vapor at the second location; and a sample analysis module that analyzes the sample collected in the sample storage and concentration module.Type: GrantFiled: September 16, 2008Date of Patent: August 21, 2012Assignee: Northrop Grumman Systems CorporationInventors: Kenneth J. Ewing, Fred Whiton, Jr., Paul G. Kahl, Jr.
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Patent number: 8242095Abstract: A method for treating a renal disease in a subject is disclosed. The method includes administering into a kidney of the subject with an effective amount of a gutless adenoviral vector containing a polynucleotide encoding a therapeutic agent. The gutless adenoviral vector contains the nucleotide sequence of SEQ ID NO:13 or SEQ ID NO:15 and expresses the therapeutic agent in a kidney tissue of the subject.Type: GrantFiled: May 12, 2010Date of Patent: August 14, 2012Assignee: BIOVEC, LLCInventors: Lakshman R. Sehgal, Jonathan Wong
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Patent number: 8236501Abstract: Methods and devices for isolating nucleic acids from a mixture containing such nucleic acids and extraneous matter are provided. In one embodiment, the method of the invention comprises passing the mixture through a glass frit under conditions effective to separate the nucleic acids from the extraneous matter. In a more specific embodiment, the glass frit is a sintered glass fit.Type: GrantFiled: June 3, 2010Date of Patent: August 7, 2012Assignee: Akonni Biosystems, Inc.Inventor: Phillip Belgrader
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Patent number: 8236553Abstract: Methods and devices for isolating nucleic acids from a mixture containing such nucleic acids and extraneous matter are provided. In one embodiment, the method of the invention comprises passing the mixture through a glass frit under conditions effective to separate the nucleic acids from the extraneous matter. In a more specific embodiment, the glass frit is a sintered glass frit.Type: GrantFiled: June 3, 2010Date of Patent: August 7, 2012Assignee: Akonni Biosystems, Inc.Inventor: Phillip Belgrader
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Patent number: 8235308Abstract: A fragrance dispensing assembly including a container having a sealed interior chamber containing porous reeds in a fragranced liquid. At least one buoyant member is coupled to one or more of the reeds. The porous reeds, buoyant member(s) and the fragranced liquid are put in the container and placed in contact with each other prior to sealing the container. To commence use of the fragrance dispensing assembly, the sealed container is opened and the buoyant member(s) elevate the coupled porous reeds within the liquid, thus providing additional portions of the pre-soaked porous reeds to extend from the opened container and begin instant and continuous fragrance dispensing to a room upon opening the sealed container.Type: GrantFiled: October 20, 2008Date of Patent: August 7, 2012Assignee: Gaines Group LLCInventors: Kelly Gaines, Andrea Garrison
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Patent number: 8236856Abstract: Methods and compositions for reducing the frequency of urination are disclosed. One method comprises administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising an analgesic agent formulated in a delayed-release formulation. Another method comprises administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising multiple active ingredients. Yet another method comprises administering to a subject in need thereof an effective amount of a diuretic followed with another administration of an pharmaceutical composition comprising an analgesic agent.Type: GrantFiled: March 19, 2012Date of Patent: August 7, 2012Assignee: Wellesley Pharmaceuticals, LLCInventor: David A. Dill
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Patent number: 8235877Abstract: An apparatus and method for stretching and/or exercising a user's body through incremental, controlled inversion and lower body stretching, preferably performed in combination. The user lies atop an exercise table and restrains her lower body to a restraint movably coupled to the exercise table. The user preferably controls the actuation of a first actuator to incrementally pivot the exercise table about a support structure thereby inverting the user's body. Before or after actuation of the first actuator, but preferably concurrently therewith, the user controls the actuation of a second actuator to incrementally extend the restraint axially away from the exercise table thereby pulling the user's lower body away from the user's upper body. This combination of gravity and mechanical decompression produces greater results than either action by itself.Type: GrantFiled: March 5, 2010Date of Patent: August 7, 2012Inventor: John P. Boren