Patents Represented by Attorney, Agent or Law Firm Anne M. Rosenblum
  • Novel 3-substituted amino-1-heteroaryl-2-pyrazolines
    Patent number: 4376122
    Abstract: This disclosure describes novel 3-substituted amino-1-heteroaryl-2-pyrazolines and their C5 analogs, effective an antibacterial and antifungal agents.
    Type: Grant
    Filed: July 13, 1981
    Date of Patent: March 8, 1983
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Joseph P. Joseph, Seymour Bernstein
  • Modulators of the complement system comprising polyhexaose arylene sulfate derivatives
    Patent number: 4374832
    Abstract: Poly-cation salts of bis- (or tris-) (polyhexaose-oxy)-arylene sulfate derivatives, useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and end products.
    Type: Grant
    Filed: December 28, 1981
    Date of Patent: February 22, 1983
    Assignee: American Cyanamid Company
    Inventors: Joseph P. Joseph, Seymour Bernstein
  • Modulators of the complement system comprising bis-glucopyranosyl arylene sulfate derivatives
    Patent number: 4374831
    Abstract: Bis-(.beta.-D-glucopyranosyl-1-oxy)-arylene sulfate derivatives, the cation salts thereof, useful as modulators of the complement system, the intermediates thereof and the process for the preparation of such intermediates and end products.
    Type: Grant
    Filed: December 28, 1981
    Date of Patent: February 22, 1983
    Assignee: American Cyanamid Company
    Inventors: Joseph P. Joseph, Seymour Bernstein
  • Naphthalenetetrayltetrakis(sulfonylimino)-tetrabenzene di- and tricarboxylic acids
    Patent number: 4369191
    Abstract: Naphthalenetetrayltetrakis(sulfonylimino)tetrabenzene di- and tricarboxylic acids and salts thereof useful as complement inhibitors and the process of making such compounds.
    Type: Grant
    Filed: July 27, 1981
    Date of Patent: January 18, 1983
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Therapeutically active 3-amino-1-phenyl and substituted phenyl-2-pyrazolines
    Patent number: 4360680
    Abstract: A method of treating pain, meliorating inflammation in warm-blooded animals as well as a method for treating fungal and bacterial infections in such animals using certain 3-amino-1-phenyl-2-pyrazolines and 3-amino-1-substituted phenyl-2-pyrazolines and their C4 and C5 analogs, as well as compounds used in the above are disclosed.
    Type: Grant
    Filed: July 13, 1981
    Date of Patent: November 23, 1982
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Joseph P. Joseph, Seymour Bernstein
  • O-.alpha.-D-Multigalactopyranosyl-O-.alpha.-D-multiglucopyranosyl-O-.beta.- D
    Patent number: 4359459
    Abstract: O-.alpha.-D-Galactopyranosyl(1.fwdarw.6)-O-.alpha.-D-galactopyranosyl(1.fwd arw.6)-O-.alpha.-D-glucopyranosyl(1.fwdarw.2)-O-.beta.-D-fructofuranosyl(1. fwdarw.6)-O-.alpha.-D-glucopyranosyl(1.fwdarw.4)-O-.alpha.-D-glucopyranosyl -.alpha.-D-glucopyranoside sulfate salts useful as complement inhibitors and the process of making such compounds.
    Type: Grant
    Filed: September 28, 1981
    Date of Patent: November 16, 1982
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, Seymour Bernstein
  • 6'-(1-Adamanta necarboxylate)-6-O-.alpha.-D-galactopyranosyl-.alpha.-D-glucopyranose sulfate salts
    Patent number: 4359460
    Abstract: 6'-(1-Adamantanecarboxylate)-6-O-.alpha.-D-galactopyranosyl-.alpha.-D-gluco pyranose sulfate salts, useful as complement inhibitors, and the process for making such compounds.
    Type: Grant
    Filed: October 13, 1981
    Date of Patent: November 16, 1982
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, Seymour Bernstein
  • O-.beta.. -D (and O-.alpha... -D) Multigalactopyranosyl, xylopyranosyl and glucopyranosyl sulfate salts
    Patent number: 4359458
    Abstract: O-.beta.-D (and O-.alpha.-D) multi-galactopyranosyl (or xylopyranosyl or glucopyranosyl) 1.alpha.,1.alpha.' galactopyranosyl (or xylopyranosyl or glucopyranosyl) sulfate salts, useful as complement inhibitors, the intermediates thereof and the process for preparation of such compounds.
    Type: Grant
    Filed: September 28, 1981
    Date of Patent: November 16, 1982
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, Joseph P. Joseph, Arthur J. Lewis, Seymour Bernstein
  • Mono-, di- and tri-adamantylcarbonyl- digalactopyranosyl- glucopyranosyl- fructofuranose sulfate salts
    Patent number: 4359461
    Abstract: Mono-, di- and tri-adamantylcarbonyl- digalactopyranosyl- glucopyranosyl- fructofuranose sulfate salts, useful as complement inhibitors and the process of making such compounds.
    Type: Grant
    Filed: October 28, 1981
    Date of Patent: November 16, 1982
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, Seymour Bernstein
  • 3-Trifluoroacetyl amino-1-aryl-2-pyrazolines
    Patent number: 4348527
    Abstract: This disclosure describes novel 3-substituted amino-1-phenyl-2-pyrazolines and 3-substituted amino-1-mono and disubstituted phenyl-2-pyrazolines and their C.sub.4 and C.sub.5 analogs, effective as anti-inflammatory and analgesic agents, and as antibacterial agents and/or antifungal agents.
    Type: Grant
    Filed: July 13, 1981
    Date of Patent: September 7, 1982
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Joseph P. Joseph, Seymour Bernstein
  • Novel 3-substituted amino-1-substituted heteroaryl-2-pyrazolines
    Patent number: 4347251
    Abstract: This disclosure describes novel 3-substituted amino-1-substituted heteroaryl-2-pyrazolines and their C.sub.4 and C.sub.5 analogs, effective as agents that ameliorate inflammation, analgesic agents, antibacterial agents and/or anti-fungal agents.
    Type: Grant
    Filed: July 13, 1981
    Date of Patent: August 31, 1982
    Assignee: American Cyanamid Company
    Inventors: Joseph P. Joseph, John P. Dusza, Seymour Bernstein
  • Modulators of the complement system
    Patent number: 4337249
    Abstract: N-(4-O-.alpha.-D-glucopyranosyl-.beta.-D-glucopyranosyl)-3,4-dihydroxycinna mamide, nonakis (H-sulfate) (nonaester), nona-alkali metal or alkaline earth metal-salts, useful as modulators of the complement system, the intermediates thereof and the process of making such salts and intermediates.
    Type: Grant
    Filed: August 3, 1981
    Date of Patent: June 29, 1982
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein