Patents Represented by Attorney, Agent or Law Firm Annette S. Parent
  • Antibacterial agents
    Patent number: 8084615
    Abstract: Antibacterial compounds of formula I are provided: As well as stereoisomers, pharmaceutically acceptable salts, esters, and prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of the compounds.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: December 27, 2011
    Assignees: University of Washington, Novartis Vaccines and Diagnostics, Inc.
    Inventors: Niels H. Andersen, Jason Bowman, Alice L. Erwin, Eric A. Harwood, Toni Kline, Khisimuzi E. Mdluli, Simon Ng, Keith B. Pfister, Ribhi Shawar, Allan S. Wagman, Asha Yabannavar
  • Method for producing fibronectin and fibrinogen compositions using a polyalkylene glycol and glycine or &bgr;-alanine
    Patent number: 6579537
    Abstract: A method of producing a pharmaceutical preparation comprising fibronectin and fibrinogen is disclosed. The method involves admixing into a starting solution of fibrinogen and fibronectin, in a single step, a precipitating composition comprising a polyalkylene glycol and at least one of glycine and &bgr;-alanine which forms a precipitate. Next, the precipitate is collected and a pharmaceutical preparation is prepared from the precipitate. The pharmaceutical preparation has a fibronectin:fibrinogen ratio from about 0.02 to about 0.2.
    Type: Grant
    Filed: February 10, 2000
    Date of Patent: June 17, 2003
    Assignee: Baxter Aktiengesellschaft
    Inventors: Thomas Seelich, Ralf Broermann
  • Fibrin/fibrinogen binding conjugate
    Patent number: 6506365
    Abstract: The invention relates to fibrin/fibrinogen binding conjugate comprising a fibrin/fibrinogen binding moiety, a substance capturing moiety capable of reversibly binding to a pharmaceutically active substance, and a pharmaceutically active substance, wherein the fibrin/fibrinogen binding moiety is bound to the substance capturing moiety, a kit for forming a depot for a pharmaceutically active substance and a method for producing a depot for a pharmaceutically active substance.
    Type: Grant
    Filed: September 25, 2000
    Date of Patent: January 14, 2003
    Assignee: Baxter Aktiengesellschaft
    Inventors: Heinz Redl, Walter Fuerst, Rudolf Kneidinger
  • Methods for treating or preventing pain
    Patent number: 6326385
    Abstract: The present invention relates to a novel method of treating of pain, using compounds that modulate KCNQ potassium channels and currents.
    Type: Grant
    Filed: August 4, 2000
    Date of Patent: December 4, 2001
    Assignee: ICAgen, Inc.
    Inventors: Alan David Wickenden, Gregory Cooksey Rigdon, Grant Andrew McNaughton-Smith, Michael Francis Gross
  • Mammalian telomerase RNA gene promoter
    Patent number: 6054575
    Abstract: Nucleic acids comprising the RNA component of a mammalian telomerase are useful as pharmaceutical, therapeutic, and diagnostic reagents.
    Type: Grant
    Filed: December 24, 1997
    Date of Patent: April 25, 2000
    Assignee: Geron Corporation
    Inventors: Bryant Villeponteau, Junli Feng, Walter Funk, William H. Andrews
  • Modulation of mammalian telomerase by peptide nucleic acids
    Patent number: 6046307
    Abstract: The invention relates to peptide nucleic acids that inhibit telomerase activity in mammalian cells.
    Type: Grant
    Filed: April 9, 1997
    Date of Patent: April 4, 2000
    Assignee: The University of Texas System
    Inventors: Jerry W. Shay, Woodring E. Wright, Mieczyslaw A. Piatyszek, David R. Corey, James C. Norton
  • Modulation of mammalian telomerase by peptide nucleic acids
    Patent number: 6015710
    Abstract: The invention relates to peptide nucleic acids that modulate telomerase activity in mammalian cells.
    Type: Grant
    Filed: April 9, 1996
    Date of Patent: January 18, 2000
    Assignee: The University of Texas System
    Inventors: Jerry W. Shay, Woodring E. Wright, Mieczyslaw A. Piatyszek, David R. Corey, James C. Norton
  • Methods for detecting the RNA component of telomerase
    Patent number: 5846723
    Abstract: Methods of detecting the RNA component of telomerase, diagnosing cancer, and determining its prognosis using polynucleotides that hybridize to the RNA component of mammalian telomerase in a sample.
    Type: Grant
    Filed: December 20, 1996
    Date of Patent: December 8, 1998
    Assignee: Geron Corporation
    Inventors: Nam Woo Kim, Fred Wu, James T. Kealey, Ronald Pruzan, Scott L. Weinrich