Abstract: This invention relates to derivatives of polyanhydroaspartic acid which are non-systemic water soluble polymers and which are intended to be lipid lowering agents. The pharmaceutical compositions/formulations incorporating these compounds are also discussed.
Abstract: This invention relates to novel 5-pyrimidineamine derivatives. The compounds of the invention exhibit cardiovascular properties, particularly mixed vasodilative, selective venous and arterial dilation. Pharmaceutical compositions are proposed for the compounds.
Abstract: Novel imidazolybenzoyl substituted heterocycles and their use as cardiovascular agents most especially as Class III antiarrhythmic agents is described. Pharmaceutical formulations containing such compounds are also discussed.
Type:
Grant
Filed:
June 20, 1990
Date of Patent:
February 23, 1993
Assignee:
Schering AG
Inventors:
Yuo-Ling Chou, Paul W. Erhardt, Alfred A. Hagedorn, III, John W. Lampe, Lumma, Jr., William C., Thomas K. Morgan, Jay R. Wiggins
Abstract: Novel quinuclidines, their acid addition, quaternary ammonium and inner salts are described. Also provided is the method of using these compounds as antiarrhythmic agents and pharmaceutical formulations containing such compounds.