Abstract: A suspension for a rear or a front portion of a chassis for vehicles in which a pair of longitudinal stabilizer assemblies and an anti-sway stabilizer each use a same type of a stabilizer bar, with the longitudinal stabilizer assemblies pivotably connected on opposing sides of the chassis and the anti-sway stabilizer pivotably connected in transverse relation proximate an end of the chassis. The longitudinal stabilizer assemblies and the anti-sway stabilizer each include a portion of a saddle that extends around the axle and rigidly connects to the axle. A shock absorber connects between the saddle and the chassis.
Abstract: A computer-implemented method of analysis of melt curve data comprising the steps of: (a) parameter model fitting the melt curve data; (b) performing a principal component analysis of the melt curve data; and (c) utilizing the principal components for clustering the melt curve data into groups. Such a method allows an efficient analysis of variations in melt curve shape and position and allows to statistically quantify these variations for both supervised and unsupervised data sets. Current melt analysis methods neither allow for statistical measures of each unknown nor do they allow for the determination of unsupervised data sets (i.e., unknown number of groups present). Particularly, the method according to the invention can be advantageous for identifying a specific sequence of dsDNA in a sample after performing a polymerase chain reaction (PCR).
Abstract: The invention relates to herbicidal compositions, their preparation, and their use for controlling unwanted vegetation. The compositions include an effective amount of an active compound combination that includes: (a) a substituted thien-3-yl-sulphonylaminocarbonyltriazolinone of formula (I-2) or salts thereof; and (b) at least one of the known herbicides listed in the disclosure and, (c) optionally a safener.
Type:
Grant
Filed:
June 28, 2010
Date of Patent:
September 18, 2012
Assignee:
Bayer Cropscience AG
Inventors:
Dieter Feucht, Peter Dahmen, Mark Wilhelm Drewes, Rolf Pontzen, Rudolf Ernst Gesing
Abstract: The subject matter of the invention relates to a system (1) and to a method for securely processing information, particularly sensitive information by means of a signature and/or encryption principle, comprising at least the following: a mobile passive first storage unit (1) for retrievably storing first information, a processing device (3) which is adapted for interacting with the first storage unit (2) in order to process information, comprising: a decryption-protected second storage unit (6) for retrievably storing second information corresponding to the first information, a computer unit (5) for (cryptographically) processing information, an information transmission unit (4), for transmitting the information of the first and/or the second storage unit (2, 6) to the computer unit (5).
Type:
Grant
Filed:
February 27, 2007
Date of Patent:
September 11, 2012
Assignee:
Bayer Innovation GmbH
Inventors:
Stephan Völkening, Hardy Jüngermann, Torsten Hupe
Abstract: Catheters for occluding, visualizing, irrigating, evacuating, and delivering agents to a treatment area are disclosed. The catheters comprise a catheter body comprising five lumens, first and second occlusion balloons coupled to the catheter body, an optional space-occupying balloon coupled to the catheter body and disposed between the first and second occlusion balloons, and an optional visualization means that enables visualization between the first and second occlusion balloons. Methods for using these catheters are also disclosed. A method comprises inflating the first and second occlusion balloons, inflating the space-occupying balloon, allowing fluid to exit via an evacuation lumen, optionally irrigating or aspirating to facilitate fluid exit via said lumen, and delivering an agent to a treatment area via the agent lumen.
Abstract: The present invention relates to immunotherapeutic methods, and molecules and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-helper cell peptide epitopes, alone or in combination with other tumor-associated peptides, that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumor immune responses. In particular, the present invention relates to 49 novel peptide sequences derived from HLA class II molecules of human tumor cell lines which can be used in vaccine compositions for eliciting anti-tumor immune responses.
Abstract: The present invention concerns a new method of preparation of a strain of evolved micro-organisms for the production of 1,2-propanediol by the metabolism of a simple carbon source, which method comprises the growth under selection pressure in an appropriate growth medium containing a simple carbon source of an initial bacterial strain that has undergone the deletion of the gene tpiA and the deletion of at least one gene involved in the conversion of methylglyoxal (propanal) into lactate, in order to cause, in said initial strain, the evolution of one or more genes involved in the biosynthesis pathway from DHAP to methylglyoxal and then to 1,2-propanediol towards evolved genes that possess an improved “1,2-propanediol synthase activity”, the resulting strain or strains of evolved micro-organisms possessing an improved “1,2-propanediol synthase activity” then being selected and isolated.
Type:
Grant
Filed:
January 12, 2005
Date of Patent:
August 28, 2012
Assignee:
Metabolic Explorer
Inventors:
Isabelle Meynial-Salles, Benjamin Gonzalez, Philippe Soucaille
Abstract: The invention concerns image data processing, through noise reduction comprising the following steps: associating a learning zone (ZA) with a reference point (Pref) of the image (IM); for each variable point (PC, PC?,) of the learning zone, evaluating a distance (d, d?,) between: values of points in a first window (f1) of the image, centered on the reference point, and values of points in a second window (f2, f?2,), of similar format as the format of the first window and centered on the variable point; repeating said distance calculation for all the points of the learning zone as successive variable points and estimating an average value to assign to the reference point, said average being weighted on the basis of the distances evaluated for each variable point.
Type:
Grant
Filed:
April 13, 2005
Date of Patent:
August 28, 2012
Assignees:
France/Ecole Normale Superieure de Cachan, France and Universitat de les Illes Balears, Centre National de la Recherche Scientifique-CNRS
Inventors:
Jean-Michel Morel, Bartomeu Coll, Antonio Buades
Abstract: The present invention concerns boosting the activity of crop protection materials comprising active ingredients from the class of the phenyl-substituted cyclic ketoenols through the addition of ammonium salts and/or phosphonium salts or through the addition of ammonium salts and/or phosphonium salts and penetrants, the corresponding materials, processes for preparing them, and their use in crop protection.
Type:
Grant
Filed:
December 11, 2006
Date of Patent:
August 21, 2012
Assignee:
Bayer Cropscience AG
Inventors:
Reiner Fischer, Stefan Lehr, Peter Marczok, Udo Reckmann, Christian Arnold, Waltraud Hempel, Erich Sanwald, Rolf Pontzen
Abstract: The present invention relates to a process for preparing 2,2-difluoroethylamine of the formula (I) and salts thereof, for example sulphates, hydrochlorides or acetates, which proceeds from difluoroacetonitrile.
Type:
Grant
Filed:
December 9, 2010
Date of Patent:
August 14, 2012
Assignee:
Bayer Cropscience AG
Inventors:
Norbert Lui, Stefan Antons, Wahed Ahmed Moradi
Abstract: The invention describes phenyl-substituted pyridazinones of the formula (I) as herbicides and insecticides. In this formula (I), A, B, G, X, Y and Z are radicals such as hydrogen, organic radicals such as alkyl, and other radicals such as halogen, nitro and cyano.
Type:
Grant
Filed:
December 15, 2009
Date of Patent:
August 14, 2012
Assignee:
Bayer Cropscience AG
Inventors:
Stefan Lehr, Thomas Schenke, Christopher Hugh Rosinger, Reiner Fischer, Isolde Häuser-Hahn, Dieter Feucht, Jan Dittgen, Pierre Cristau, Oliver Gaertzen, Stefan Herrmann, Olga Malsam, Eva-Maria Franken
Abstract: The present invention relates to an organopolysiloxane composition that can be vulcanized at room temperature into an elastomer that is crosslinked by polycondensation and that does not contain alkyltin-based catalysts and also to novel organopolysiloxane polycondensation catalysts.
Type:
Grant
Filed:
November 18, 2008
Date of Patent:
August 14, 2012
Assignee:
Bluestar Silicones France S.A.S.
Inventors:
Christian Maliverney, Laurent Saint-Jalmes
Abstract: The present disclosure pertains to a blend of aromatic polycarbonate and polylactic acid, the method for preparing the same and the use thereof. In the present invention a transesterification catalyst is added during the preparing process with regard to the blend of aromatic polycarbonate and polylactic acid to improve the compatibility of the components in the blend. The blend of aromatic polycarbonate and polylactic acid is provided with the good mechanical properties, thermal processibility and flame retardance properties, and can be widely applied to mechanical product or parts, electronic equipments and/or parts, construction material and/or commodities.
Abstract: A method and apparatus for remotely detecting, locating, and identifying chemicals and chemical compounds through optically opaque materials. Electromagnetic radiation in the Terahertz range emitted from an antenna array is modulated to excite target molecules. The apparatus then stops the excitation energy and the molecules emit an electromagnetic signature detectable by the device at standoff distances.
Abstract: The invention relates to a tumor-associated peptide with an amino acid sequence selected from the group consisting of SEQ ID NO. 1 to SEQ ID NO. 577 from the attached sequence protocol, the peptide being capable of binding to a molecule of the human major histocompatibility complex (MHC) class I. The invention further relates to the use of the peptides for preparation of a drug and for the treatment of tumor diseases and/or adenomatous diseases. Furthermore, a pharmaceutical composition is described comprising at least one of the peptides.
Type:
Grant
Filed:
August 19, 2009
Date of Patent:
August 14, 2012
Assignee:
Immatics Biotechnologies GmbH
Inventors:
Toni Weinschenk, Claudia Lemmel, Hans-Georg Rammensee, Stefan Stevanovic
Abstract: A system and related methods for the management and evaluation of real estate appraisals comprising, a method of determining a standardized score representative of the accuracy and quality of a real estate appraisal. Data from the appraisal is extracted and evaluated according to a plurality of compliance and risk based rules applicable to the type of appraisal. Each rule is given a particular weight, and an appraisal score may be calculating by summing each instance of a rule triggered multiplied by the weight assigned to that rule. Weights may be set by experts, or determined by statistical analysis.
Type:
Grant
Filed:
October 31, 2007
Date of Patent:
August 14, 2012
Assignee:
FNC, Inc.
Inventors:
Kathy Coon, Gwen Magrisso, Robert Dorsey
Abstract: The present invention relates to a pesticide composition intended for protecting plants, crops or seeds against phyto-pathogenic fungi or damaging insects, and the corresponding methods of treatment using the said composition. More precisely, the subject of the present invention is a pesticide composition based on propamocarb-fosetylate, an insecticide active substance and optionally a further fungicide active substance.
Type:
Grant
Filed:
December 21, 2007
Date of Patent:
August 7, 2012
Assignee:
Bayer Cropscience AG
Inventors:
Koen Van Den Eynde, Marc Andrieux, Heike Hungenberg, Wolfgang Thielert, Anne Suty-Heinze
Abstract: The present invention relates to compounds as inhibitors of enzymes having histone deacetylase activity, to the processes for the preparation of those compounds, and to their use for the treatment of diseases which are associated with hypoacetylation of histones and/or other molecules, or in which induction of hyperacetylation has a beneficial effect for example by inhibition of proliferation and/or induction of differentiation and/or induction of apoptosis in transformed cells, such as cancer. Furthermore, the compounds are useful for the treatment of other proliferative diseases, for therapy or prophylaxis of conditions associated with abnormal gene expression.
Type:
Grant
Filed:
July 16, 2007
Date of Patent:
July 24, 2012
Assignee:
4SC Discovery GmbH
Inventors:
Alexander B. Maurer, Sascha Hoevelmann, Elke Martin, Bernd Hentsch, Michael Gassen, Juergen Kraus, Rolf Krauss, Adam-Spencer Vincek
Abstract: A safety stocking (10) in the form of a sock (11) includes an elastic, stretchable fabric portion (12) and a patterned anti-skid tread (13). The foot section (14) has a top surface (19) and a bottom surface (20). Both the top surface and the bottom surface are joined to the anti-skid tread. The anti-skid tread pattern extends continuously and symmetrically from a first point (23) adjacent the toes of a wearer to a second point (24) adjacent the heal of a wearer.