Abstract: A building structure formed from modular building elements, which include first modular building elements (1,9) having socket beam interconnection means (2), second modular building elements (13,14,15) and socket beams (7, 11) having first modular building element interconnection means (6); whereby a socket beam (7,11) forms an interconnection with at least one first modular building element (1,9) and at least one second modular building element (13, 14, 15) associates with a socket beam (7,11) and first modular building element interconnection, a socket beam (7,11) and at least one first modular building element (1,9) and at least one second modular building element (13,14,15) forming a configuration unit, the configuration unit being repeatable one atop the other, and being repeatable in a side-by-side fashion, a first modular building element associating or abutting with adjacent first modular building elements, a second modular building elements associating or abutting with adjacent second modular buildin

Abstract: The locking bolt of a swing bolt lock has an elongated opening that fits on a shaft in the lock's housing. The shaft has a compression spring that biases the bolt toward one side of the shaft. In normal operation, the compression spring urges the bolt such that the shaft is at one end of the elongated opening. There, the swing bolt pivots about the shaft to unlock the lock. When a person tries to force the lock, the elongated opening of the bolt moves against spring bias along the shaft. In one embodiment, flat surfaces in the opening and on the shaft engage each other and a notch on the outside surface of the bolt engages a stationary safety key. This prevents the bolt from applying sufficient force to break weaker parts within the lock mechanism and force the lock open.

Abstract: The invention relates to a cartridge for packaging an analyte-containing fluid calibrant. The cartridge is formed from a container having an opening sealed by a sealing member. A septum divides the container into a calibrant compartment and an outer compartment. A probe is provided comprising an analyte-detecting portion and a connecting portion that allows for operative connection to a device for quantitating or determining the concentration of the analyte. The probe may extend sealingly through the septum such that the analyte-detecting portion is located in the calibrant compartment and the connecting portion is located in the outer compartment. The construction of the cartridge provides ease and reduces the likelihood of error in calibrating the probe. The invention also relates to a method of manufacturing the cartridge and a method for calibrating a device for analyte concentration determination and quantitation using the inventive cartridge.

Abstract: An apparatus and method of use are disclosed to treat and/or diagnose urological disorders. The non-implantable device includes a light source housed within a light source segment. The light source segment is of a sufficiently small size and configuration so that it can be inserted through the urethra and positioned adjacent the target site in the patient. Different types of light sources can be used to achieve a variety of energy levels and distributions useful in treating incontinence disorders. Both incoherent and coherent light sources may be used with the present invention. In addition, the light from the light source can be designed to be pulsed or continuous wave and may be in any suitable spectrum, including visible (such as white light) and infrared. The particular characteristics of the light emitted from the light source, such as wavelength, frequency, amplitude, etc., depend upon the particular treatment and procedure.

Abstract: A method for cleaning the lumens of a medical device such as an endoscope by providing a flow and a reverse flow of fluids in interconnected lumens of the medical device.

Abstract: A device and method for cleaning and sterilizing tubular structures particularly, long, narrow tubular structures such as lumens of a medical device such as an endoscope by reversing the flow of fluid in interconnected tubular structures. The device comprises a first and second valve in fluid communication with a first and second tubular structure. The valves selectively switch between a first and second position causing a first and second flow path within the tubular structures, at least a part of the second flow path opposite the first flow path.

Abstract: A packaging system for a sterilizable item comprising a pouch having a frangible opening, the pouch defining a sterile compartment therein to hold a sterilizable item and a support element for fluid attachment to a sterilizer, the support element defining a window thereupon, the support element attached to the pouch along a perimeter of the opening. The opening may comprise a scored portion cut into the front side of the pouch. The support element may be a rigid cardboard support element defining a perforated window with a knockout piece. The system may also include a cover adhered with the window for ensuring that the knockout piece remains attached to the support element until broken. The system may also include an adhesive strip attached along a perimeter of the cover, and include a removable backing strip.

Abstract: A method of cleaning precleaning the header of a used dialyzer is provided. The method includes providing a precleaner header selectively coupled to a dialyzer header cap. The precleaner header includes a needle having an inlet in fluid communication with a source of cleaning fluid and an outlet in fluid communication with the header cap. An incoming source of cleaning fluid is introduced into the needle at a pressure above ambient pressure and an incoming source of air is introduced at a pressure above ambient pressure into the incoming cleaning fluid stream. The cleaning fluid containing air is discharged into the dialyzer header and cleans the dialyzer header by circulating therewith in. A waste stream is generated and drained from the dialyzer header through the precleaner header.

Abstract: A dialyzer precleaning system for coupling a source of fluid to a used dialyzer. The precleaning system includes a precleaner header that includes a housing with a needle receiving channel and a connected waste discharge channel, a needle with a plurality of fluid discharge perforations is received within the needle assembly receiving channel, and a coupling arm for attaching the precleaner header to a dialyzer header cap. The needle protrudes into the dialyzer header so that fluid may be discharged through the inside of the needle out the fluid discharge perforations into the dialyzer header. Waste fluid from the dialyzer header is discharged back into the needle assembly receiving channel along the outside the needle into a fluidly connected waste discharge channel and out a waste discharge outlet. The needle may also rotate and retract.

Abstract: A method for improving priming of an integrated oxygenator and heat exchanger which includes pretreating the integrated hollow fiber oxygenator and heat exchanger device with a surfactant. Pretreating the device coats the interior surfaces of the integrated hollow fiber oxygenator and heat exchanger with the surfactant, which facilitates the removal of entrapped air. An integrated hollow fiber oxygenator and heat exchanger having a surfactant coating on the interior surfaces is provided which subsequently allows for more efficient priming with an aqueous priming media.

Abstract: A method is provided for priming a hollow fiber oxygenator which is integrated with a hollow tube heat exchanger. A closed priming circuit is created between a cardiosurgery reservoir, the combined hollow fiber oxygenator and heat exchanger and a vacuum source. Vacuum pressure is applied to the closed priming circuit to evacuate the residual air from the circuit. Priming solution is released from the cardiosurgery reservoir and fills the evacuated closed priming circuit.

Abstract: An asymmetrical, microporous, hollow fiber membrane is made from a polymeric dope mixture of polysulfone and polyvinyl pyrrolidone dissolved in an aprotic solvent. The physical morphology of the hollow fiber membrane, i.e., the asymmetric microporous wall, is rapidly formed by passing the polymeric dope mixture through an outer annular orifice of a tube-in-orifice spinneret while simultaneously passing a precipitating solution through the central tube of the spinneret. The emerging hollow fiber travels substantially downward for about 0.01-10 m before submersion into a quenching bath. The asymmetrical, microporous, hollow fiber membrane is biocompatible and suitable for use in, for example, dialysis, hemodialysis, ultrafiltration, and water filtration applications.

Abstract: A low prime, high heat exchange efficiency oxygenator is provided which includes an oxygenation portion and a heat exchanger portion. Disposed within the heat exchanger portion is a hollow tube heat exchanger wound bundle which includes a plurality of hollow tubes knitted into a mat, the mat wound under tension into a bundle which includes from 16 to 24 layers of the mat. The oxygenator provided permits prime volumes of 180 to 240 mLs.

Abstract: An asymmetric, microporous hollow fiber membrane comprising a polyimide is disclosed. The hollow fiber membrane is chemically inert to aqueous solutions and/or blood, is immediately rewettable after repeated steam and chemical sterilizations, has superior clearance, sieving, and water permeability characteristics and is usable over a wide range of applications such as dialysis and water filtration. Also disclosed is the process for manufacturing the polyimide hollow fiber membrane.

Abstract: Provided is an anti-microbial composition containing an ester of formic acid, an oxidizer, performic acid and water. Also provided is a premix for making the anti-microbial composition having two parts. One part contains the ester of formic acid and a second part contains the oxidizer. Another method is provided for making the anti-microbial composition in which the ester of formic acid is combined with the oxidizer and water.

Abstract: A dialysate filter including asymmetric, microporous, hollow fiber membranes incorporating a polyimide. The dialysate filter connects to the dialysis machine immediately before the dialyzer ensuring complete filtration of the dialysate, easy visual inspection, quick installation and removal, and easy disinfection of the filter.

Abstract: Provided is an anti-microbial composition containing an ester of formic acid, an oxidizer, performic acid and water. Also provided is a premix for making the anti-microbial composition having two parts. One part contains the ester of formic acid and a second part contains the oxidizer. Another method is provided for making the anti-microbial composition in which the ester of formic acid is combined with the oxidizer and water. Also provided is a method for sterilizing devices by contacting the surface of the device with the anti-microbial composition containing the ester of formic acid, an oxidizer, performic acid and water.

Abstract: A combination heat exchanger and oxygenator device is provided. The device includes a generally cylindrical housing having first and second compartments with hollow heat exchange tubes and hollow gas exchange tubes disposed therein, a blood inlet, a blood outlet, a heat exchanges medium inlet, a heat exchange medium outlet, an oxygenating fluid inlet and an oxygenating fluid outlet. The housing has a central axis with the second compartment being concentric thereto. The blood flow passage is defined by blood entering the device generally axially through a path extending along the central axis of the housing and flows generally radially through the second, oxygenating compartment.

Abstract: A unique hollow fiber filter cartridge that allows repeated autoclaving without any deleterious breaks in sealing integrity between the potted fiber bundle and the filter module is disclosed. The unique filter cartridge braodly includes a casing that has at least one open end with an inner lip in the casing proximal to the open end; and a porous collar that has first and second peripheral edges, at least one of which is coupled to the casing along the inner ledge.

Abstract: A dialysate filter including asymmetric, microporous, hollow fiber membranes incorporating a polyimide. The dialysate filter connects to the dialysis machine immediately before the dialyzer ensuring complete filtration of the dialysate, easy visual inspection, quick installation and removal, and easy disinfection of the filter.