Patents Represented by Attorney, Agent or Law Firm Barry J. Marenberg, Esq.
  • Efficient method of synthesizing combretastatin A-4 prodrugs
    Patent number: 6743937
    Abstract: Methods of synthesizing a phosphate ester of combretastatin A-4 and trans-isomers thereof in which combretastatin A-4 is reacted with dibenzylphosphite in the presence of carbon tetrabromide, or with 2,2,2-trichloroethyl phosphorodichloridate, to form a phosphate ester of combretastatin A-4 with protecting groups thereon.
    Type: Grant
    Filed: July 17, 2001
    Date of Patent: June 1, 2004
    Assignee: OxiGene, Inc.
    Inventors: Faye Seyedi, Jonathan Gale, Reem Haider, John Hoare, Amy Baldwin
  • Process for the preparation of derivatives of octafluoro-[2,2] paracylophane
    Patent number: 6392097
    Abstract: Processes for the preparation of parylene dimers, and more particularly to processes for the preparation of derivatives of octafluoro-[2,2]paracylophane, otherwise known as AF4.
    Type: Grant
    Filed: March 20, 2001
    Date of Patent: May 21, 2002
    Assignee: Specialty Coating Systems, Inc.
    Inventors: William R. Dolbier, Jr., Jian-Xin Duan, Alex J. Roche