Abstract: Gene expression in a cell can be regulated or inhibited by incorporating into or associating with the genetic material of the cell a non-native nucleic acid sequence which is transcribed to produce an mRNA which is complementary to and capable of binding to the mRNA produced by the genetic material of said cell.

Abstract: This invention concerns a new product consisting of TiO.sub.2 particles having pigmentary granulometric and morphological characteristics. It includes a chemically reactive coating consisting of a mixture of oxides and oxychlorides selected from the group consisting of Al.sub.2 O.sub.3 and AlOCl; SiO.sub.2 and SiOCl.sub.2 ; and ZrO.sub.2 and ZrOCl.sub.2.The particles of reactive TiO.sub.2 product are prepared as follows: the surface of the TiO.sub.2 particles is activated by thermally treating the particles in a moving bed with an anhydrous gas at 400.degree.-600.degree. C. The particles are then made to react in a moving bed at 350.degree. C. to 600.degree. C., in the presence of a carrier gas, with an inorganic chloride selected from the group consisting of AlCl.sub.3, SiCl.sub.4 and ZrCl.sub.4.This new product is useful, for instance, in TiO.sub.2 pigments coated with organic molecules which provide an affinity for the vehicles of paints.

Abstract: Coal-aqueous mixture characterized by having high coal solids concentrations are provided. Selected polyalkyleneoxide nonionic surfactants are employed at low concentrations to disperse coal in an aqueous carrier medium to coal solids levels of 70% by weight, or higher. The selected polyalkyleneoxide nonionic surfactants are characterized by having a high molecular weight and a hydrophilic portion comprised of at least about 100 repeating units of ethylene oxide.

Abstract: An improved technique is provided for forming coal into a stabilized coal-oil mixture. Coal, in a fine mesh size, is admixed with oil, a monomeric compound, a reaction initiator and a reaction catalyst at elevated temperatures and under a condition of low shear. The coal mixture is thereafter immediately subjected to a condition of high shear at the maintained elevated temperature. The mixture is then admixed with a gelling agent to form a stable coal-oil mixture. According to the technique, coal of significantly greater water content than heretofore thought acceptable, is formed to a stable coal-oil mixture in a ready manner. In addition, the amount of monomeric compound heretofore thought needed to form the desired stable mixture is substantially reduced, resulting in improved process efficiency.In its preferred aspect, the process is adapted to treat raw coal which has first been subjected to pulverization, chemical surface treatment, separation from ash and sulfur, and drying.