Patents Represented by Attorney, Agent or Law Firm Blossom F. Loo
  • Method for treating cross-linked biological tissues
    Patent number: 6322593
    Abstract: A method for treating biological tissue is provided in which a cross-linked biological tissue containing free aldehyde groups is reacted with a suitable neutralization agent in order to chemically block the aldehyde groups from reactivity toward cellular proteins. Also provided is the cross-linked biological tissue so produced which is substantially free of reactive aldehyde groups and, as a result, exhibits reduced toxicity and improved biocompatibility.
    Type: Grant
    Filed: April 9, 1999
    Date of Patent: November 27, 2001
    Assignee: Sulzer Carbomedics Inc.
    Inventors: Chandrashekhar P. Pathak, Mark A. Moore, Richard E. Philips, Jr.