Patents Represented by Attorney, Agent or Law Firm Brenda Herschback Jarrell
  • Patent number: 6824987
    Abstract: The present invention provides compositions and methods to facilitate the identification of compounds that are capable of interacting with a biological macromolecule of interest. In one aspect, a composition is provided that comprises an array of one or more types of chemical compounds attached to a solid support, wherein the density of the array of compounds is at least 1000 spots per cm2. In particularly preferred embodiments, these compounds are attached to the solid support through a covalent interaction.
    Type: Grant
    Filed: May 10, 2000
    Date of Patent: November 30, 2004
    Assignee: President and Fellows of Harvard College
    Inventors: Stuart L. Schreiber, Gavin MacBeath, Angela N. Koehler, Paul Hergenrother, Kristopher M. Depew
  • Patent number: 6808707
    Abstract: The present invention provides compositions and methods for promoting wound healing. The composition comprises virgin monomers of tropoelastin and lysyl oxidase. When the lysyl oxidase comes in contact with the tropoelastin, cross-linking of the tropoelastin monomers will occur to form elastin. Contacting the tropoelastin and lysyl oxidase together and applying the mixture to a wound before substantial cross-linking has occurred promotes wound healing by holding the damaged tissue together, increasing the rate of healing, and decreasing the amount of scarring.
    Type: Grant
    Filed: February 4, 2000
    Date of Patent: October 26, 2004
    Assignee: Matrix Design
    Inventor: Burt D. Ensley