Abstract: A drug delivery device having a base member defining a skin-contacting surface, a syringe serving as a reservoir for the drug, and means for expelling drug from the syringe. The syringe is connected to the base member such that the longitudinal axis of the syringe is substantially parallel to the skin surface. A delivery needle is in communication with the syringe. The needle has an angled bend which directs the tip of the needle substantially perpendicular to the skin-contacting surface. In use, the tip of the needle is adapted to penetrate the skin of the subject.

Abstract: A method for manufacturing a tamper-indicating closure having a plurality of resilient flexible projections bent upwardly and radially inwardly at a predetermined radius of curvature. The first step in the method includes providing a mold assembly comprising a female mold portion for forming the outer surface of the closure and a male mold portion for forming the closure's inner surface and its plurality of projections. The male and female mold portions are arranged for relative movement toward and away from each other between a mold open position and a mold closed position. When in the mold closed position, the male and female mold portions define a mold cavity in which the tamper-indicating closure is molded.

Abstract: An apparatus for supporting the head of user while the user is lying in a face-down position, a face-up position or a side position. The apparatus includes a head cradle with air holes and a pair of elongated dependent arms that can be manipulated to serve as a chest support, or a neck support or a head support depending on how the user is lying.

Abstract: A system and method of use for effecting the bypass or other anastomosis of a portion of a native blood vessel, duct, lumen or other tubular organ within the body of a living being. The system includes a connector assembly and a deployment instrument for carrying the device to the desired position within the vessel, duct, lumen or tubular organ. The system includes a piercer-dilator instrument to form an opening in the wall of the vessel, duct, lumen or tubular organ into which the connector assembly is deployed by the deployment instrument. The connector assembly is at least partially formed of a resorbable material and includes movable members for securing it to the tissue of the vessel, duct, lumen or tubular organ contiguous with the opening. Other components may be included in the device for expediting the anastomosis procedure, with or without the use of sutures.

Abstract: A system and method of use for effecting the bypass or other anastomosis of a portion of a native blood vessel, duct, lumen or other tubular organ within the body of a living being. The system includes an anastomosis connector device and a deployment instrument for carrying the device to the desired position within the vessel, duct, lumen or tubular organ. The deployment device may include a dilator to facilitate the placement of the anastomosis device within the interior of the vessel, duct, lumen or other tubular organ. The anastomosis device is preferably formed of a resorbable material and is configured to minimize blood or other fluid turbulence therethrough. The device may include snap-connectors or other components for securing it to the tissue of the vessel, duct, lumen or tubular organ and hemostasis-inducing sealing rings to prevent blood leakage. Other components may be included in the device for expediting the anastomosis procedure, with or without the use of sutures.

Abstract: A container (20) made of a rigid tubular conformation, each end (21, 22) of which is flattened to produce and provide outwardly protruding edges (25). A transition portion (33) between the flattened end portion (22) and undeformed body portion has a sloped wall in which at least one access aperture (24) is formed. The aperture (24) is selectively closed by a plug, valve or cap adapted to be secured in a fluid-tight manner in this container (20). Hand hold apertures (e.g., 23) may be formed where the ends are sealed. Disposable or reusable bladders, bags and/or liners (58, 70) can be used with these containers, and can be extended out of the fitting (50, 72) and can be gathered together and sealed (59) to provide a sanitary and tamper-proof covering. The container (20) may be pressurized if desired. An expanding plug assembly (100) having a body (102) formed of a pair of resilient members (104, 106) separated by a thin plate or diaphragm (108) also forms a part of this invention.