Abstract: An enveloped vector particle contains gag and pol proteins from a retrovirus, a nucleic acid sequence and an envelope that includes VSV G envelope glycoprotein. The vector particle can be used to introduce nucleic acids into cells.
Type:
Grant
Filed:
December 22, 1994
Date of Patent:
October 6, 1998
Assignees:
The Regents of the University of California, Chiron Viagene, Inc.
Inventors:
Jiing-Kuan Yee, Nobuhiko Emi, Theodore Friedmann, Douglas J. Jolly, Jack R. Barber