Patents Represented by Attorney Charles L. Hartman
  • Patent number: 5178217
    Abstract: Gas-condensate having an API gravity value greater than 55.degree. is produced by injecting (1) a light noncondensable gas and (2) a foaming agent comprising a surfactant and water into a subterranean formation containing the gas condensate.
    Type: Grant
    Filed: July 31, 1991
    Date of Patent: January 12, 1993
    Assignee: Union Oil Company of California
    Inventors: Shane S. Mohammadi, John D. Collins
  • Patent number: 5128042
    Abstract: Non-brackish water can be produced from the brackish water or brine containing at least 500 ppm total dissolved solids coproduced in many active hydrocarbon product wells and found in many inactive gas wells. The brackish water or brine is desalinated producing non-brackish water, preferably, potable water. A preferred method of desalination is by reverse osmosis.
    Type: Grant
    Filed: June 27, 1991
    Date of Patent: July 7, 1992
    Assignee: Union Oil Company of California
    Inventor: Donald M. Fenton
  • Patent number: 5076934
    Abstract: Non-brackish water can be produced from the brackish water found in many inactive oil wells. The inactive well is perforated at the level known to have brackish water and the water is pumped out. The brackish water is desalinated producing non-brackish water, preferably, potable water. A preferred method of desalination is by reverse osmosis.
    Type: Grant
    Filed: February 21, 1991
    Date of Patent: December 31, 1991
    Assignee: Union Oil Company of California
    Inventor: Donald M. Fenton
  • Patent number: 4618696
    Abstract: This invention covers a compound of the formula ##STR1## wherein R is hydrogen, lower alkyl or a pharmaceutically acceptable, non-toxic salt of a compound wherein R is hydrogen; and X is hydrogen, halo, trifluoromethyl, lower alkyl or lower alkoxy; and the wavy lines represent the .alpha. or .beta. configuration with the proviso that when one wavy line is .alpha. the other is .beta..
    Type: Grant
    Filed: July 31, 1984
    Date of Patent: October 21, 1986
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Gary F. Cooper, John A. Edwards, Albert R. Van Horn
  • Patent number: 4600785
    Abstract: This invention relates to a process for making an enantiomer or racemic mixture of a compound of the formula ##STR1## wherein R is hydrogen, lower alkyl or a pharmaceutically acceptable, non-toxic salt of a compound wherein R is hydrogen; X is hydrogen, halo, trifluoromethyl, lower alkyl or lower alkoxy, and the wavy lines represent the .alpha. or .beta. configuration with the proviso that when one wavy line is a .alpha. the other is .beta.; novel intermediates useful for preparing these compounds; and processes for making the intermediates.
    Type: Grant
    Filed: December 22, 1983
    Date of Patent: July 15, 1986
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Gary F. Cooper, Douglas L. Wren, Albert R. Van Horn, Tsung-Tee Li, Colin C. Beard
  • Patent number: 4599331
    Abstract: This invention provides a method for inhibiting angiogenesis in mammals. A pharmaceutically acceptable formulation containing a compound of the formula ##STR1## where X.sub.1 X.sub.2 and X.sub.3 are H, C1, or F and X.sub.3 must be H if the substituent of R.sub.1 is .alpha.OH;R.sup.1 is chosen from the group consisting of hydroxyl and hydrogen;R.sub.2 is chosen from the group of alkyloxy or thioalkyls wherein said alkyls have less than 5 carbon atomsR.sub.3 is H or an alkyl having less than 6 carbon atoms, is administered to the mammal having undesirable angiogenesis.The wavy line at C-16 refers to either .alpha. or .beta..
    Type: Grant
    Filed: December 24, 1984
    Date of Patent: July 8, 1986
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Alain B. Schreiber, William J. Kowalski, Stefan H. Unger
  • Patent number: 4591592
    Abstract: A novel pharmaceutical composition which comprises an acid salt of a thieno-pyridine derived compound, a pharmaceutically acceptable, non-volatile organic acid (particularly citric acid) and optionally other suitable pharmaceutical excipients.
    Type: Grant
    Filed: October 29, 1984
    Date of Patent: May 27, 1986
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: Zaka-ud-Din T. Chowhan
  • Patent number: 4567264
    Abstract: Novel compounds of the general formula ##STR1## and the pharmaceutically acceptable esters and acid addition salts thereof, wherein:R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are each independently hydrogen, lower alkyl, lower alkoxy, cyano, trifluoromethyl, halo, lower alkylthio, lower alkyl sulfinyl, lower alkyl sulfonyl, N-optionally substituted alkylamido, except that when R.sup.1 is methyl, R.sup.4 is not methyl; orR.sup.2 and R.sup.3 together form --OCH.sub.2 O--;R.sup.6, R.sup.7, R.sup.8, R.sup.9 and R.sup.10 are each independently hydrogen, lower acyl, aminocarbonylmethyl, cyano, lower alkyl, lower alkoxy, trifluoromethyl, halo, lower alkylthio, lower alkyl sulfinyl, lower alkyl sulfonyl, di-lower alkyl amino; orR.sup.6 and R.sup.7 together form --CH.dbd.CH--CH.dbd.CH--;R.sup.7 and R.sup.8 together form --OCH.sub.2 O--;R.sup.11 and R.sup.12 are each independently hydrogen or lower alkyl; andW is oxygen or sulfur.
    Type: Grant
    Filed: May 18, 1983
    Date of Patent: January 28, 1986
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Arthur F. Kluge, Robin D. Clark, Arthur M. Strosberg, Jean-Claude G. Pascal, Roger Whiting
  • Patent number: 4548951
    Abstract: Compounds of the formula ##STR1## and the pharmaceutically acceptable, nontoxic, acid addition salts thereof, whereinR.sub.1 and R.sub.2 are each independently --H, lower alkyl, or cycloalkyl, with the proviso that R.sub.1 and R.sub.2 cannot both be --H or cycloalkyl at the same time;R.sub.1 and R.sub.2 taken together are cycloalkyl of 4-7 carbons;n is 0 or 1;X is (CH.sub.2).sub.2, CH.dbd.CH, or C.tbd.C;Y is independently selected from the group of --H, --Fl, --Br, --Cl, lower alkyl, and --OR.sub.3 ; wherein R.sub.3 is --H or lower alkyl; anda is 1 or 2, ortwo Y's taken together are --OCH.sub.2 O--;are useful as regulators of the cardiovascular system, particularly as hypotensive agents.
    Type: Grant
    Filed: April 21, 1983
    Date of Patent: October 22, 1985
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Joseph M. Muchowski, Jack Ackrell
  • Patent number: 4532318
    Abstract: A method for removing trace amounts of contaminating hydrazine from pharmaceutical grade PVP. An aqueous solution of PVP is contacted with a gaseous stream containing ozone for a period of time sufficient to remove the hydrazine.
    Type: Grant
    Filed: September 5, 1984
    Date of Patent: July 30, 1985
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Allassan Abubakari, Alfred H. Holstein
  • Patent number: 4530920
    Abstract: Synthetic nonapeptide and decapeptide LHRH agonists analogs having a novel gaunadino-substituted, amidine, tertiary or quatrinary aminoacyl residue at position 6 are disclosed herein.
    Type: Grant
    Filed: November 7, 1983
    Date of Patent: July 23, 1985
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: John J. Nestor, Brian H. Vickery
  • Patent number: 4497818
    Abstract: 2-(1,4-Benzodioxan-2-ylalkyl)imidazoles having the general formula: ##STR1## wherein R.sup.1, and R.sup.2 and R.sup.3 are independently selected from the group consisting of hydrogen, and alkyl (1-6C), and wherein n is an integer equal to 0, 1 or 2, and the pharmaceutically acceptable acid addition salts thereof, are .alpha..sub.2 blockers and thus are useful as affectors of the CNS, specifically as platelet aggregation inhibitors and as antihypertensives.
    Type: Grant
    Filed: August 5, 1981
    Date of Patent: February 5, 1985
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Arthur F. Kluge, Arthur M. Strosberg, Roger L. Whiting, George A. Christie
  • Patent number: 4497827
    Abstract: Novel compounds of this invention are tetrazole, acylhydroxylamine, hydroxymethylketone and amide derivatives of unsaturated fatty acids which are selective inhibitors of the enzymes lipoxygenase and cyclooxygenase involved in the production of pain, inflammation, bronchoconstriction and allergic reactions. These compounds are beneficial in the treatment of a number of inflammatory and/or painful conditions and allergic reactions.
    Type: Grant
    Filed: August 30, 1982
    Date of Patent: February 5, 1985
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: Peter H. Nelson