Abstract: Lipopolyamines useful for the transfection of nucleic acid and methods of preparation thereof are disclosed. The lipopolyamines are of general formula I, in which R4 comprises at least one C10-C22 aliphatic radical.
Type:
Grant
Filed:
May 13, 1998
Date of Patent:
January 9, 2001
Assignee:
Aventis Pharma S.A.
Inventors:
G{acute over (e)}rardo Byk, Daniel Scherman, Bertrand Schwartz, Catherine Dubertret