Abstract: Formula (I) wherein R1 is a (2-4C)alkyl and is substituted by two or more fluorine groups and R2 is methyl or ethyl, or a pharmaceutically acceptable salt thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by metalloproteinase enzymes.

Abstract: A rotating contact supporting shaft for a low-voltage power circuit breaker, whose particularity consists of the fact that it has a modular structure that comprises, along the rotation axis, at least one first and one second supporting module (10, 20), each module being functionally coupled to at least one corresponding moving contact (3) of the circuit breaker and being provided respectively with first and second means (22) for connection to at least one first interconnection module (30); the first interconnection module is interposed between the first and second supporting modules and is provided with third and fourth connection means (31) that are suitable to be coupled respectively to the first and second connection means; the coupling between the first and third connection means and between the second and fourth connection means allows the functional connection between the first and second supporting modules and the direct structural connection of the interconnection module to the first and second suppor

Abstract: A redox flow battery composed of a plurality of cells in electrical series defined by a stacked and repetitive arrangement of a conductive intercell separator having a generally bipolar function, a positive electrode, an ion exchange membrane, a negative electrode and another conductive intercell separator, is operated by flowing a positive half-cell electrolyte containing reducible and oxidizable ions of a first redox couple through the compartments containing the positive electrodes and a negative half-cell electrolyte containing reducible and oxidizable ions of a second redox couple through the compartments containing the negative electrodes in cascade in a counter or equi-current mode. The difference of cell voltage between the first and the last cell of the stack is sensibly reduced and by-pass currents are substantially eliminated thus resulting in an increased overall faradic efficiency.