Abstract: A protein consisting essentially of purified human minor vault protein p193 or purified biologically active variants thereof, or a combination of purified human minor vault protein p193 and biologically active variants thereof. Also, a polynucleotide molecule encoding a protein which consists essentially of human minor vault protein p193, or its complementary strands. Further, there is provided a method of diagnosing and a method of treating patients with multidrug resistant cancer.
Type:
Grant
Filed:
June 3, 1998
Date of Patent:
December 5, 2000
Assignee:
The Regents of the University of California