Abstract: A probe assembly samples fluid from a wellbore penetrating a subsurface formation having a virgin fluid therein beyond a layer of contaminated fluid surrounding the wellbore. The probe assembly includes a probe body extendable from a downhole tool, and a packer carried by the probe body and having a distal surface adapted for sealingly engaging the wellbore. The packer has an outer and inner periphery, with the inner periphery being defined by a bore through the packer. The packer is further equipped with channel(s) formed in the distal surface and arranged to define an annular cleanup intake intermediate the inner and outer peripheries. The passageway(s) extend(s) through the packer for conducting virgin fluid and/or contaminated fluid between the channel(s). A sampling tube is sealingly disposed in the bore of the packer for conducting virgin fluid to a second inlet in the probe body and the downhole tool.