Patents Represented by Attorney David L. Weinstein
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Patent number: 7932826Abstract: A system and method for the tracking of medical instrument, components, assemblies, and sub-assemblies thereof, and maintenance information relating to the foregoing. According to the system, radio frequency identification tags are attached to or affixed on the medical instrument itself for the purpose of locating, identifying, monitoring, tracking the medical instrument and updating the maintenance and replacement activities relating to the medical instrument. In addition, radio frequency identification tags are attached to or affixed on the components, the assemblies, and the sub-assemblies, of the medical instrument in order to locate, identify, monitor, track the components, the assemblies, and the sub-assemblies and update the maintenance and replacement activities relating to these components, assemblies, and sub-assemblies.Type: GrantFiled: June 12, 2008Date of Patent: April 26, 2011Assignee: Abbott Laboratories Inc.Inventors: Patrick P. Fritchie, Oscar F. Schwartz, Renee A. Lopez
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Patent number: 7858924Abstract: An optic module verification device for normalizing between X photon counters, including a verification tray with X verification wells and a modular photon emitter in each verification well. Each photon emitter includes a spring, a Beta source disk, a scintillator disk adjacent the Beta source disk, and a neutral density filter over the scintillator disk, all of which are encapsulated in a cylindrical chamber with the filter adjacent an opening on one end of the chamber and the spring biasing the Beta source disk and the scintillator disk toward the opening. The device is periodically used for normalization, and may be updated when emitted photons fall below a desired level by replacing the scintillator disk and then determining a new normalized reference values for each photon emitter.Type: GrantFiled: December 12, 2006Date of Patent: December 28, 2010Assignee: Abbott Laboratories, Inc.Inventors: Paul A. Matuszewski, Omar S. Khalil, Kurt M. Klosterman, James L. Dempski, Jose Pioquinto
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Patent number: 7815866Abstract: A reaction vessel with a bottom drain opening supporting a selected unpressured head of fluid by the surface tension of the fluid. A device processing zone includes a support for spaced rows of reaction vessels, passages communicating with their drain openings of supported vessels, and a pressure source for selectively draining fluid through the drain openings. Generally horizontal bar magnets are supported for selected vertical movement between the vessel rows. A dispensing head has X discharge openings selectively positionable over X selected reaction vessels. A metering pump mechanism selectively meters X a selected quantity of fluid a bulk supply (where X is at least four), and selectively pumps the metered selected quantities through the drain openings to the selected reaction vessels. Methods of drawing fluid from the vessels using the pressure source, and moving the magnets to form a pellet of analyte are also included.Type: GrantFiled: June 17, 2009Date of Patent: October 19, 2010Assignee: Abbott Laboratories, Inc.Inventors: Scott G. Safar, Stephen L. Herchenbach, Chadwick M. Dunn, Charles M. Galitz, Julius J. Toth, Ronald E. Kukla, Michael G. Lowery, Eric B. Shain
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Patent number: 7814788Abstract: An apparatus and method for determining the level of liquid in a container in an analytical instrument, typically an automated analytical instrument in a laboratory. The apparatus comprises: (a) an electrically conductive support; (b) an electrically conductive platform rising up from said electrically conductive support, said platform capable of supporting at least one container that is capable of containing a liquid, said platform having an area less than that of the electrically conductive support; (c) an electrically conductive element, such as, for example, the electrically conductive tip of a probe, the distance between the electrically conductive platform and the electrically conductive element capable of being reduced or increased by relative movement between the electrically conductive element and the electrically conductive platform; and (d) a capacitance sensor coupled to the electrically conductive element (c) and arranged to provide an electrical signal representing the capacitance.Type: GrantFiled: October 20, 2006Date of Patent: October 19, 2010Assignee: Abbott Laboratories, Inc.Inventors: Folim G. Halaka, Ronald E. Kukla, Scott G. Safar
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Patent number: 7804594Abstract: A method for increasing the throughput, or the precision, or both the precision and the throughput, of a flow cytometer, or of a hematology analyzer employing a flow cytometer, by utilizing the technique of laser rastering. Laser rastering involves sweeping a laser beam across a flowing sample stream in a hematology analyzer. An apparatus suitable for carrying out the method of this invention comprises an optical module comprising a source of light, a scanning device, a lens or system of lenses, a flow cell, detectors, and filters; and an electronic module comprising preamplifiers, analog signal conditioning elements, analog-to-digital converters, field-programmable gate arrays, digital signal processing elements, and data storage elements.Type: GrantFiled: November 2, 2007Date of Patent: September 28, 2010Assignee: Abbott Laboratories, Inc.Inventors: Giacomo Vacca, Norman R. Goldblatt, Michael W. Yee
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Patent number: 7790363Abstract: An isolated nucleotide sequence or fragment thereof encoding the porcine intrinsic factor, wherein the porcine intrinsic factor comprises an amino acid sequence having at least 85% amino acid sequence identity to an amino acid sequence selected from the group consisting of SEQ ID NO: 3, SEQ ID NO: 6, and SEQ ID NO: 9. The invention also encompasses an isolated nucleic acid sequence or fragment thereof comprising, or complementary to, a nucleotide sequence having at least 85% nucleotide sequence identity to a nucleotide sequence selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 4, and SEQ ID NO: 7. The porcine intrinsic factor can be use is an assay to determine the quantity of vitamin B12 in a biological sample.Type: GrantFiled: February 7, 2005Date of Patent: September 7, 2010Assignee: Abbott Laboratories Inc.Inventors: Ramani S. Wonderling, John F. Uher
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Patent number: 7776263Abstract: An apparatus for mixing a liquid in a container in order to provide a homogeneous solution or suspension of the liquid in the container. In particular, the apparatus of this invention can be used to provide a homogenous dispersion of particulate material in a liquid medium.Type: GrantFiled: October 26, 2005Date of Patent: August 17, 2010Assignee: Abbott Laboratories Inc.Inventor: Richard C. East
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Patent number: 7688207Abstract: A system for automation of laboratory analyzers that utilizes radio frequency identification (RFID) tags and radio frequency identification (RFID) readers to identify containers and vessels, and the contents thereof, that are employed in the system. Radio frequency identification tags, conforming to the guidelines of ISO 14443 or ISO 15693 or ISO 18000, are positioned on the items of interest, such as, for example, reagent containers, sample containers, and microplates. These tags can be read by and written to by either a moving antenna of a RFID reader or a stationary antenna of a RFID reader. Reading of RFID tags and writing to RFID tags are controlled by software.Type: GrantFiled: July 28, 2006Date of Patent: March 30, 2010Assignee: Abbott Laboratories Inc.Inventors: Patrick P. Fritchie, Gregory E. Gardner, Richard W. Mahoney, Oscar F. Schwartz
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Patent number: 7678337Abstract: A slide holder comprising a rectangular frame having two side walls facing each other, a first end wall facing a second end wall, the second end wall having a latch pivotally attached thereto, the latch capable of being pivoted in such a manner as to enable locking and unlocking of the slide holder in a slide holder carrier. The slide holder carrier has a first end wall, a first side wall, a second end wall, a second side wall, and a shaft running from the first end wall of the slide holder carrier to the second end wall of the slide holder carrier. At least one slide holder is rotatably mounted on the shaft.Type: GrantFiled: April 26, 2005Date of Patent: March 16, 2010Assignee: Abbott Laboratories Inc.Inventors: Russell L. Sage, Robert W. Jaekel
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Patent number: 7678331Abstract: A module for staging sample tubes and mixing the samples contained in the sample tubes for an automated clinical analyzer. In one embodiment, this module comprises a mixing drum, which is capable of mixing the contents of a sample tube in an end-over-end manner. The mixing drum is capable of mixing samples in the sample tubes without separating the solid components of the sample, e.g., red blood cells from the liquid components of the sample, e.g., plasma. A device for elevating the sample tube in the sample tube carrier can be used to enable the cap of the sample tube to be punctured by a piercing element in a piercing assembly. After the cap of the sample tube is punctured, a probe for aspirating the sample from said sample tube can obtain the sample in the receptacle of the sample tube through a bore in the piercing element. The piercing assembly can include a resiliently biased element for ejecting the sample tube from the piercing assembly.Type: GrantFiled: December 20, 2007Date of Patent: March 16, 2010Assignee: Abbott Laboratories Inc.Inventor: Ronald J. Shanafelter
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Patent number: 7674622Abstract: A method for enumerating white blood cells and nucleated red blood cells. The steps of the method are as follows: (a) providing a lysed sample of whole blood; (b) introducing the lysed sample to a light-scattering multi-angle depolarizing flow cytometer; (c) removing depolarizing interference, e.g., lipid droplets and other measured particles; (d) differentiating nucleated red blood cells and noise from white blood cells in the absence of depolarizing interference; (e) differentiating nucleated red blood cells from noise in the absence of depolarizing interference and white blood cells; and (f) differentiating possible platelet clumps.Type: GrantFiled: December 22, 2006Date of Patent: March 9, 2010Assignee: Abbott Laboratories, Inc.Inventors: Diana G. Garrett, Hyejung C. Lee, Show-Chu Wong, Bodo Roemer, Sherb M. Edmondson, Jr.
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Patent number: 7628954Abstract: A handling device for samples and reagents to be used in testing in a system. Carriers of samples and reagents are loaded on a platform which detects the presence of, and proper loading of, such carriers. The carriers are moved from the platform by a transporter to a bar code reader for identification. A reagent container is rotated during reading to facilitate identification. The transporter further moves identified reagent carriers to a carousel on which the carriers automatically secured for storage awaiting use in testing. The carousel rotates, and selected reagent containers rotate on the rotating carousel, during storage.Type: GrantFiled: May 4, 2005Date of Patent: December 8, 2009Assignee: Abbott Laboratories, Inc.Inventors: Cordell Kay Gomm, Robert Paul Luoma, II, David Charles Arnquist, Ryan Patrick Johnson
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Patent number: 7621282Abstract: The invention provides probe washing cups and methods. A probe washing cup has a washing well and a waste cup. A drying section is disposed between an open end of the probe washing cup and an inlet plane of the washing well. The drying section has a channel that is aligned with the washing well. The channel has an opening for receiving the probe therethrough.Type: GrantFiled: June 17, 2004Date of Patent: November 24, 2009Assignee: Abbott Laboratories, Inc.Inventors: Gregory A. Blackwell, Ganesh Rajagopal
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Patent number: 7565250Abstract: A method and system for determining the quantity of an analyte initially present in a chemical and or biological reaction as well as a computer implemented method and system to automate portions of the analysis comprising mathematical or graphical analysis of an amplification reaction.Type: GrantFiled: November 17, 2004Date of Patent: July 21, 2009Assignee: Abbott Laboratories Inc.Inventors: Eric B. Shain, John M. Clemens, Tzyy-Wen Jeng, George J. Schneider
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Patent number: 7458483Abstract: A diagnostic system with a handling system that has a loading bay to receive and hold a plurality of carriers. An identification device is configured to identify an identifying feature of the carriers to determine the type of contents loaded on each carrier. A transporter transports the carriers from the loading bay to a first or second location depending on the determined type of contents on each carrier. The transporter has random access to the plurality of carriers in the loading bay. A diagnostic process is conducted using the contents. A carrier, such a for reagents, has one or more holding portions, at least one of which can be moved or rotated with respect to the body of the carrier for mixing or stirring the contents of a container coupled therewith. Also, a retention member can be associated with a positioning device, such as a carousel, to lock and unlock the carrier with respect thereto.Type: GrantFiled: July 7, 2003Date of Patent: December 2, 2008Assignee: Abbott Laboratories, Inc.Inventor: Robert Paul Luoma, II
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Patent number: 7380654Abstract: A conveyor track drive includes a continuous loop conveyor for supporting and carrying a specimen container, with one portion of the conveyor extending through a drive housing. The conveyor includes a first segment extending through the housing, which then wraps around a portion of a drive sprocket, extends back upstream and around a portion of an idler sprocket and then includes a second segment transversely adjacent the first segment. A guide plate on the housing is positioned over the adjacent segments of the conveyor with a slot located to guide a specimen carrier from the first segment to the second segment. The specimen carrier then exits the housing on the second segment of the conveyor. A motor in the housing drives the drive sprocket to move the conveyor.Type: GrantFiled: July 24, 2003Date of Patent: June 3, 2008Assignee: Abbott LaboratoriesInventors: Douglas Barry, Adrian Chan, Greg Rothman, Don R. Simms, Inna M. Zevakina
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Patent number: 7351586Abstract: The present invention relates methods for making stable calibrators and controls that can be used in ligand-binding assays.Type: GrantFiled: October 12, 2005Date of Patent: April 1, 2008Assignee: Abbott Laboratories Inc.Inventors: Judith A. Friese, Matthew S. Matias, Ray A. Weigand
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Patent number: D559115Type: GrantFiled: December 6, 2004Date of Patent: January 8, 2008Assignee: Abbott LaboratoriesInventor: David Heisner
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Patent number: D569260Type: GrantFiled: December 6, 2004Date of Patent: May 20, 2008Assignee: Abbott LaboratoriesInventor: David Heisner
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Patent number: D605041Type: GrantFiled: January 3, 2008Date of Patent: December 1, 2009Assignee: Abbott Laboratories, Inc.Inventors: James P. Perry, Ashley A. Gohlke, William J. Hook, Katherine J. Jordan, Frank S. Walczak, Peter B. Clarke, J. Kevin Clay