Patents Represented by Attorney, Agent or Law Firm David R. Marsh
  • Molecular farming
    Patent number: 6774283
    Abstract: Novel constructs are provided for expression of physiologically active mammalian proteins in plant cells, either in culture or under cultivation. The constructs provide a promoter functional in a plant host, a structural gene coding for mammalian protein and a terminator functional in a plant host. The construct is introduced into a plant cell to become integrated into the plant genome for expression in the plant cells or plants. The plant cells may be harvested and the mammalian protein isolated in physiologically active form.
    Type: Grant
    Filed: November 23, 1999
    Date of Patent: August 10, 2004
    Assignee: Calgene LLC
    Inventors: Robert M. Goodman, Vic C. Knauf, Catherine M. Houck, Luca Comai
  • Polynucleotides encoding proexendin, and methods and uses thereof
    Patent number: 6723530
    Abstract: Exendin 4 is a biologically active peptide first isolated from Gila monster venom. The invention encompasses polynucleotides encoding proexendin peptides, including exendin and novel peptides, as well as isolated or recombinant proexendin peptides. The invention also includes antibodies which specifically recognize such peptides.
    Type: Grant
    Filed: February 5, 1998
    Date of Patent: April 20, 2004
    Assignee: Amylin Pharmaceuticals, Inc.
    Inventor: Daniel J. Drucker