Abstract: A process for fabricating shaped material from demineralized bone particles includes the steps of applying a liquid slurry of demineralized bone particles to a support, removing excess liquid form the demineralized bone particles to provide a cohering shaped mass of demineralized bone particles, and warming the shaped mass of demineralized bone particles at a predetermined temperature and for a predetermined time period. The resultant bone mass exhibits enhanced tensile strength and minimal bone particle disassociation upon rehydration thereby improving product handling and application at the operative site.
Type:
Grant
Filed:
September 18, 1998
Date of Patent:
August 20, 2002
Assignee:
Osteotech, Inc.
Inventors:
Michael Dowd, Nelson L. Scarborough, Mark Daugherty, Jack McMickle
Abstract: The effectiveness of an anticonvulsant such as gabapentin for alleviating neuropathic pain is potentiated by a nontoxic antagonist for the N-methyl-D-aspartate receptor or nontoxic substance that blocks a major intracellular consequence of N-methyl-D-aspartate receptor activation.
Type:
Grant
Filed:
February 9, 2001
Date of Patent:
June 18, 2002
Assignee:
Endo Pharmaceuticals Inc.
Inventors:
Frank S. Caruso, Fredrick L. Minn, John W. Lyle
Abstract: To at least considerably diminish or even completely prevent rain water from being driven inward in a strong wind, the front face (9) of the front slab segment (61) has horizontal grooves (68, 69, 70).