Patents Represented by Attorney Donna E. Becker

Find this attorney in the Justia Lawyer Directory

  • Surface mediated self-assembly of nanoparticles
    Patent number: 8288169
    Abstract: Materials and methods for surface mediated self-assembly of nanoparticles for the isolation of biomolecules is provided.
    Type: Grant
    Filed: March 24, 2008
    Date of Patent: October 16, 2012
    Assignee: Argylla Technologies
    Inventors: Joseph G. Utermohlen, Michael E. Hogan, Paul E. Diggins
  • Colony assay miniaturization with enumeration output
    Patent number: 7989178
    Abstract: A system combining a clonogenic differentiation assay with an instrument-based ATP bioluminescence proliferation assay to produce a standardized colony-forming stem and progenitor cell potency assay is provided.
    Type: Grant
    Filed: June 6, 2008
    Date of Patent: August 2, 2011
    Assignee: Hemogenix, Inc.
    Inventor: Ivan N. Rich
  • Nanoparticles for manipulation of biopolymers and methods of thereof
    Patent number: 7964380
    Abstract: Matrices for manipulation of biopolymers, including the separation, purification, immobilization and archival storage of biopolymers is disclosed.
    Type: Grant
    Filed: January 23, 2006
    Date of Patent: June 21, 2011
    Assignee: Argylia Technologies
    Inventors: Joseph G. Utermohlen, Michael E. Hogan, Paul Diggins
  • High throughput assay of hematopoietic stem and progenitor cell proliferation
    Patent number: 7883861
    Abstract: The present invention relates generally to kits that provide reagent mixes and instructions for the use thereof, in performing high-throughput assay methods that determine the proliferative status of isolated target cell populations. The methods measure the luminescent output derived from the intracellular ATP content of incubated target cells, and correlate the luminescence with the proliferative status of the cells. The present invention further relates to kits that provide reagent mixes and instructions for high-throughput assays methods for screening compounds that may modulate the proliferative status of a target cell population. The kits of the present invention and methods therein described may be used for determining the proliferative status of any isolated cell line or type. The kits and methods of the present invention address the need for rapid assays that determine the proliferative status of isolated hematopoietic stem and progenitor cells and of subpopulations of differentiated cells thereof.
    Type: Grant
    Filed: March 17, 2008
    Date of Patent: February 8, 2011
    Assignee: HemoGenix, Inc.
    Inventor: Ivan N. Rich
  • High throughput assay for identifying compounds capable of modulating the proliferative status of stem cells
    Patent number: 7709258
    Abstract: The present invention relates generally to high-throughput assay methods that determine the proliferative status of hematopoietic stem and progenitor cells. The present invention further relates to high-throughput assays for screening compounds that modulate the growth of hematopoietic stem and progenitor cells and for identifying subpopulations thereof that are suitable for transplantation. The assay of the present invention is particularly useful for quality control and monitoring of the growth potential in the stem cell transplant setting and would provide improved control over the reconstitution phase of transplanted cells.
    Type: Grant
    Filed: March 17, 2008
    Date of Patent: May 4, 2010
    Assignee: HemoGenix, Inc.
    Inventor: Ivan N. Rich
  • High throughput stem cell assay for identifying stem cells useful for transplantation
    Patent number: 7700354
    Abstract: The present invention relates generally to high-throughput assay methods that determine the proliferative status of hematopoietic stem and progenitor cells. The present invention further relates to high-throughput assays for screening compounds that modulate the growth of hematopoietic stem and progenitor cells and for identifying subpopulations thereof that are suitable for transplantation. The assay of the present invention is particularly useful for quality control and monitoring of the growth potential in the stem cell transplant setting and would provide improved control over the reconstitution phase of transplanted cells.
    Type: Grant
    Filed: March 17, 2008
    Date of Patent: April 20, 2010
    Assignee: HemoGenix, Inc.
    Inventor: Ivan N. Rich
  • High-throughput assay of hematopoietic stem and progenitor cell proliferation
    Patent number: 7666615
    Abstract: The present invention relates generally to assays, methods, and kits that provide reagent mixes and instructions for determining the proliferative status of isolated target cell populations. The methods measure the luminescent output derived from the intracellular ATP content of incubated target cells, and correlate the luminescence with the proliferative status of the cells.
    Type: Grant
    Filed: November 17, 2006
    Date of Patent: February 23, 2010
    Assignee: HemoGenix, Inc.
    Inventor: Ivan N. Rich