Patents Represented by Attorney, Agent or Law Firm Elaine Stracker
  • Xanthene dyes and their application as luminescence quenching compounds
    Patent number: 6399392
    Abstract: The quenching compounds of the invention are nitrogen-substituted xanthenes that are substituted by one or more aromatic or heteroaromatic quenching moieties. The quenching compounds of the invention exhibit little or no observable fluorescence and efficiently quench a broad spectrum of luminescent compounds. The chemically reactive quenching compounds possess utility for labeling a wide variety of substances, including biomolecules. These labeled substances are highly useful for a variety of energy-transfer assays and applications.
    Type: Grant
    Filed: April 21, 2000
    Date of Patent: June 4, 2002
    Assignee: Molecular Probes, Inc.
    Inventors: Richard P. Haugland, Victoria L. Singer, Stephen T. Yue