Abstract: The present invention relates to compounds, compositions and methods for treating a disease in an animal, which disease is responsive to inhibiting of functional cystic fibrosis transmembrane conductance regulator (CFTR) polypeptide by administering to a mammal in need thereof an effective amount of a compound defined herein (including those compounds set forth in Tables 1-2 or encompassed by formulas Ia, Ib, IIa, and IIb) or compositions comprising these compounds, thereby treating the disease. The present invention particularly, relates to a method of treating diarrhea and polycystic kidney disease.

Abstract: A method is for producing propylene oxide, the method including the steps of: reacting hydrogen peroxide with propylene either in an acetonitrile solvent or in a mixture of solvents which include acetonitrile and water, in presence of a titanosilicate catalyst, whereby a reaction mixture containing propylene oxide is obtained; separating the reaction mixture obtained in the reacting into a gas and a reaction liquid; and distilling the reaction liquid obtained in the separating, whereby the reaction liquid is separated into a column top liquid containing propylene oxide, and a column bottom liquid including acetonitrile or a combination of acetonitrile and water, in combination with other steps. This enables industrially efficient production of propylene oxide with use of acetonitrile.

Abstract: A data element that is identical to a part of a plurality of data elements stored in a logical storage device (LU hereinbelow) is stored in a storage area (pool hereinbelow) separate from the LU. A first PDEV (physical storage device) that stores the data element stored in the LU may be placed in a power saving state while the storage system is operating (in periods when a read command can be received), and a second PDEV which stores the data element stored in the pool is not placed in a power saving state during operation. When the storage system receives a read command which is received from the host apparatus, and if the first PDEV is in the power saving state and a data element identical to the data element which is the target of the read command is stored in the pool, the storage system reads the identical data element from the pool without canceling the power saving state of the first PDEV, and sends the read data element to the host apparatus.

Abstract: A semiconductor device may include, but is not limited to: a semiconductor substrate having an element formation region and a dicing region; an element layer over the element formation region and the dicing region; and a multi-layered wiring structure over the dicing region. The multi-layered wiring structure extends upwardly from the element layer. The multi-layered wiring structure has a groove penetrating the multi-layered wiring structure.

Abstract: A blend of at least two polymers in combination with a drug provides a pressure-sensitive adhesive composition for a transdermal drug delivery system in which the drug is delivered from the pressure-sensitive adhesive composition and through dermis when the pressure-sensitive adhesive composition is in contact with human skin.

Abstract: It is an object of the present invention to provide a rubber composition having: excellent sealing properties, heat resistance and acid resistance; a low reaction force, low hardness and low compression set; and excellent low-temperature recovery properties that contribute to sealing properties particularly in low-temperature environment. It is another object of the invention to provide uses of the rubber composition and main bodies on which the rubber composition has been mounted. The rubber composition of the present invention comprises a specific ethylene/?-olefin/non-conjugated polyene copolymer [A], a SiH group-containing compound [B] having two SiH groups in one molecule, and a SiH group-containing compound [C] having three SiH groups in one molecule.

Abstract: A dihydric phenol compound represented by the following formula (2), a phosgene compound, and an aliphatic tertiary amine are mixed together using a hydrophobic organic solvent to produce bischloroformate that is represented by the following formula (1) and has an average number of repeating units (n) of 1.99 or less. In the formulae (1) and (2), Ar is a divalent aromatic group.

Abstract: A braking force control device for a vehicle comprises a controller that includes an automatic-brake selective-actuation section configured to compare a manual braking force created by a manual brake device with a required braking force for an automatic brake device and to selectively actuate the automatic brake device when the required braking force exceeds the manual braking force; a braking-force-difference time-rate-of-change calculation section configured to calculate a braking-force-difference time-rate-of-change corresponding to a rate of change per unit time in a difference, which difference is obtained by subtracting the required braking force from the manual braking force; and a required braking force control section configured to correct the required braking force to reduce the required braking force when selectively actuating the automatic brake device and to correct a reducing amount of the required braking force to decrease the reducing amount of the required braking force as the braking-force-d

Abstract: An encoder structure for an error correcting code with arbitrary parity positions is presented. The invention is effective for all error correcting codes whose parity check matrix is of the Vandermonde type. In contrast to conventional encoder circuits, the parity symbols produced by this encoder are not restricted to form a block of consecutive parity symbols at the beginning or at the end of a codeword, but may be spread arbitrarily within the codeword. A general structure of the parity check matrix for such a code is found by exploiting the special Vandermonde structure of matrices. From this general parity check matrix, an expression for the evaluation of the parity symbols in terms of a polynomial with limited degree is derived. An efficient hardware implementation of the proposed encoder is suggested.

Abstract: A mounting system for the display of an audio/visual product. A cable-based mounting system for an audio/visual product includes at least one hanging cable and at least one attachment mechanism. The at least one attachment mechanism is configured to operatively engage with a plurality of various mounting patterns located on the rear of the audio/visual product. The cable-based mounting system allows for the relatively inexpensive and uncomplicated mounting of the audio/visual product on a display region.

Abstract: The present invention relates to a method for detecting ATP in a sample by using luminescence, wherein a luminescence reagent is added to the sample that has not undergone any pre-treatment with an extractant in order to effect the formation of an ATP complex, wherein the luminescence of the ATP com lex thus formed is measured.

Abstract: When a lane-width-direction lateral position (X2obst+X0) of a vehicle (MM) reaches a predetermined control start position (60) being a lane-width-direction lateral position (X2obst+X0) serving as an approach prevention indicator for the vehicle (MM), a control start is determined and a yaw moment (Ms) toward the center of a vehicle traveling lane (200) is applied to the vehicle (MM) to control the vehicle (MM). Then, when the lane-width-direction lateral position (X2obst+X0) of the vehicle (MM) moves from the outside to the inside of the control start position (60), the determination of control start is suppressed for a predetermined period, compared to a period before the movement to the inside of the control start position (60).

Abstract: An apparatus and method for making a trim panel. The method includes providing a preform laminate including a compressible material sandwiched between a flexible skin and a back skin. Positioning the preform laminate in the mold. Placing an insert with the preform laminate in the mold to created a step to establish a seam location and define a secondary area on the preform laminate. Compressing the compressible material by introducing a molten polymeric material to the mold forming a substrate and bonding the substrate to the preform laminate forming the trim component. The preform laminate folds onto itself and creates a crease along the step to simulate the seam and provide a contour change with the appearance of cushioning in the secondary area, and removing the trim panel component from the mold.

Abstract: Techniques are disclosed for stitching images printed by a multi-head printer in a manner that is relatively insensitive to misregistration of the image segments. When a pair of overlapping print heads print a pair of adjacent image segments which meet in a stitching region, printing at each location in the stitching region is accomplished by both print heads with a weighting that depends on the location being printed within the stitching region. In one embodiment, for example, the output of each print head is weighted by a linear function of horizontal pixel position. Techniques are also disclosed for selecting screening patterns for use when stitching is performed with variable-dot printers. Such screening patterns are selected to minimize variations in density that may arise as the result of cross-web and/or down-web misregistration.

Abstract: A vehicle deck board 1 is molded in such a manner that a lower die 21 and an upper die 22 are clamped together in a state where foamed resins 13 and reinforcements 20 are interposed between a back surface side sheet material 16 and a front surface side sheet material 15, whereby the back surface side sheet material 16 and the front surface side sheet material 15 are welded to each other to thereby form a laminated member 26 with height-increasing bridge members included therein, compressed air is injected into an inside of the laminated member 26 with the height-increasing bridge members included therein, which is formed by welding the back surface side sheet material 16 and the front surface side sheet 15, while individually vacuum-sucking the back surface side sheet material 16 and the front surface side sheet material 15 to the lower die 21 and the upper die 22, and the laminated member 26 concerned is subjected to blow molding.

Abstract: A semiconductor device 100 including an internal circuit 4 that operates based on an input pattern includes a clock driver 25 that generates an internal clock 7 based on a generated clock 6, a counter 23 that generates count data 28 by counting the generated clock 6, a nonvolatile storage device 22 that stores storage data 27 used in an IDDQ test, a comparator 24 that stops the generation of the internal clock 7 by the clock driver 25 when the count data 28 and the storage data 27 match each other, and a pseudo random number generation circuit 3 that supplies a pseudo random number 8 to the internal circuit 4 in synchronization with the internal clock 7.

Abstract: It has been discovered that certain combinations compounds are excellent penetration enhancers and, as such, can be incorporated in a topical formulation to facilitate administration of active agents. The increased penetration enhancement can also lead to a reduction in the total concentration of skin irritants in the formulation. There is described herein a topical formulation comprising (i) at least one active agent; (ii) a first compound, and (iii) a second compound, wherein the first compound and second compound are different, and each is selected from the group consisting of N-lauroyl sarcosine, sodium octyl sulfate, methyl laurate, isopropyl myristate, oleic acid, glyceryl oleate and sodium lauryl sulfoacetate.

Abstract: In three-dimensional data generation unit 120, data edition unit 122, generates a spreadsheet data that includes information relating to a plurality of node points on a continuous arrangement route of target components by interactive process with a user, and stores the data in storage unit 130. Three-dimensional data conversion unit 123, on the basis of spreadsheet data, arranges the node points in a three-dimensional space, connects node points having a predetermined relationship using line segments, and imparts cross-sectional shapes to the connected line segments, to carry out thereby conversion into target component arrangement three-dimensional data. Three-dimensional data management unit 124 stores the obtained target component arrangement three-dimensional data in storage unit 130, in a format readable by three-dimensional CAD or three-dimensional review system, and outputs the data in response to an output instruction from interface unit 110.

Abstract: A liquid applicator contains a hollow body portion incorporating a reservoir portion for containing a liquid to be applied by the applicator; an outlet portion having first and second ends, the first end being connected to an outlet mouth of the reservoir; an applicator tip assembly provided on the second end of the outlet portion for discharge of liquid from the reservoir portion via said outlet portion; a plug located in the mouth of the reservoir portion; and actuator for applying an actuating force to the mouth wall to effect movement of the plug towards the outlet portion and for squeezing the walls of the reservoir portion to effect discharge of liquid from the reservoir portion via the outlet portion and the applicator device. The liquid to be dispensed is retained in a reservoir that is sealed by a plug until usage.