Abstract: Isolated polynucleotide molecules and peptides encoded by these molecules can be used in the analysis of alloantigen phenotypes, as well as in diagnostic and therapeutic applications, relating to human platelet Pen polymorphism. By analyzing genomic DNA or amplified genomic DNA, or amplified cDNA derived from platelet mRNA, it is possible to type glycoprotein GPIIIa with regard to the Pen polymorphism, for example, in the context of diagnosing and treating clinical syndromes associated with GPIIIa-related immune responses.
Type:
Grant
Filed:
June 7, 1995
Date of Patent:
July 14, 1998
Assignee:
The Blood Center Research Foundation, Inc.
Abstract: In accordance with the present invention, stabilized dispersions of collagen fibers that have been treated in order to inactivate infectious agents and methods of stabilizing such collagen fibers are provided.
Type:
Grant
Filed:
July 13, 1994
Date of Patent:
April 1, 1997
Assignee:
Collagen Corporation
Inventors:
Vivek N. Shenoy, Timothy T. Revak, George H. Chu, Hugh R. McMullin, Joel S. Rosenblatt, George R. Martin