Abstract: An apparatus and method is provided for stenting bifurcated vessels. A proximal angled stent is configured for implanting in a side-branch vessel wherein the proximal angled stent has an angulated portion that corresponds to the angle formed by the intersection of the side-branch vessel and the main vessel so that all portions of the side-branch vessel at the bifurcation are covered by the proximal angled stent. A main-vessel stent is provided for implanting in the main vessel, wherein the main-vessel stent has an aperture or stent cell that aligns with the opening to the side-branch vessel to permit unobstructed blood flow between the main vessel and the side-branch vessel. Side-branch and main-vessel catheter assemblies are advanced over a pair of guide wires for delivering, appropriately orienting, and implanting the proximal angled stent and the apertured stent.
Abstract: A self-expanding filter has a deployable resilient distal portion with properties of passing fluid (e.g. blood) in a vessel (e.g. an artery) and blocking the passage of emboli in the fluid. The self-expanding filter is disposed in the vessel, in the direction of fluid flow in the vessel, with its resilient proximal and distal ends at positions past a lesion in the vessel. The distal end of the self-expanding filter is then deployed against the vessel wall. An interventional device, such as an expandable member (e.g. balloon) and expandable stent are disposed in the vessel at the position of the lesion in the vessel. The expandable member is then dilated to expand the expandable stent against the vessel wall and open the vessel at the lesion position. Fluid (blood) flows through the deployed distal end of the self-expanding filter and emboli created during the procedure are trapped by the deployed distal end of the filter.
Abstract: An intravascular stent assembly for implantation in a body vessel, such as a coronary artery, includes undulating circumferential rings having peaks on the proximal end and valleys on the distal end. Adjacent rings are coupled together between peaks on one ring and valleys on the proximally adjacent ring. To increase flexibility of the stent, the links do not couple all of the peaks on a ring to the proximally adjacent ring.
Abstract: The forks of a bicycle are carried by a head tube shaft and are angled forward and comprise two outer support tubes, one on either side of the wheel. An inner suspension tube is telescopically housed in the outer tube and connects to the wheel axle. A suspension spring within the outer tube urges down. A torque reaction arm is journalled on the axle and carries a brake calliper within which passes a brake disc. At the rear end of the arm, a rear link is pivotally connected and leads up to an upper pivot point on the outer tube. Application of braking torque causes the rear link to act upwards on the outer tube, providing anti-dive.
Abstract: A chain comprises links formed from bar stock having a specific cross-section. In a preferred embodiment, which is a chain of 16 mm size, the cross-section comprises four convex arcuate sides (10a), (10b), (10c) and (10d), each of which has a radius of curvature at least 10% greater than the chain size (i.e. at least 10% greater than 8 mm) and preferably at least 15% greater than the chain size. In this way, a chain is produced which has the profile which is similar to the profile attained by the chain after a significant period of wear, involving a significant increase in the surface-to-surface contact between adjacent links, reducing the effective wear rate, and reducing the rate of effective lengthening of the chain due to wear.
Abstract: The method for immune serum globulin purification relates to the purification of immune globulins from blood plasma with a high degree of efficiency and a high rate of recovery. The immune globulin source is Cohn's fraction I+II+III or II+III prepared from plasma or plasma intermediates by precipitation of the paste at pH 5.7 to 5.8 in the presence of 20% ethanol and 80% purified water. A glycine extraction is followed by an anion exchange chromatography column step to achieve a significantly high yield and high purity of the concentrated protein.
Type:
Grant
Filed:
October 19, 2001
Date of Patent:
May 17, 2005
Assignee:
Hemacare Corporation
Inventors:
Joshua Levy, Fred Rothstein, Bahman Shimiaei
Abstract: An apparatus for removing a solid object from a body canal or vessel includes a coil of wire configured to slidably receive a guide wire and a sack having a mouth and a closed bottom opposite the sack. A resilient frame is connected between the coil of wire and the sack for biasing the mouth of the sack open around the coil of wire. The resilient frame is positionable between a collapsed state where the mouth of the sack is closed against the bias of the resilient frame and a deployed state where the mouth of the sack is biased open by the resilient frame.
Abstract: A self-expanding stent for implantation into a body lumen, such as an artery, includes a plurality of radially expandable cylindrical elements generally aligned on a common longitudinal stent axis and interconnected by a plurality of interconnecting members placed on the stent in a collinear arrangement to create at least one continuous spine which extends along the length of the stent. The cylindrical elements are nested when placed in a collapsed position. The cylindrical elements may include a W-shared portion to which the interconnecting members attach.
Type:
Grant
Filed:
June 17, 2003
Date of Patent:
May 17, 2005
Assignee:
Advanced Cardiovascular Systems, Inc.
Inventors:
Daniel L. Cox, Matthew J. Fitz, William James Harrison, Michael D. Schultz, Joseph A. Ventura
Abstract: The invention is generally directed to an intraluminal catheter with an improved transition between a proximal shaft portion and a more flexible distal shaft portion and a method for making the same. The improvement provides enhanced flexibility, reduced bunching, and kink-resistance, thus, facilitating advancement through tortuous anatomy. The present catheters may be used for either or both angioplasty and stent deployment.
Abstract: Medical devices having at least a component, such as a catheter balloon, stent cover and vascular graft, formed of ultrahigh molecular weight polyolefin, such as ultrahigh molecular weight polyethylene. The device component is formed from ultrahigh molecular weight polyethylene that has been processed so that it is microporous and has an oriented node and fibril structure. The device component expands compliantly at low strains and are substantially less compliant at higher strains. The invention also comprises methods for making such medical devices, including the steps of compacting a polyethylene powder and deforming it to impart the oriented structure.
Abstract: A heat exchange fluid supply system for supplying a heat exchange fluid to an intravascular heat exchange catheter includes a disposable cassette having a bulkhead and an external heat exchanger, and which is configured to operate in combination with a reusable master control unit. The bulkhead includes a reservoir section and a pump section. The reservoir section is provided with a means to monitor the amount of heat exchange fluid that is in the system. The bulkhead provides the mechanism for priming the system with heat exchange fluid from an external source and for circulating fluid to the catheter in a closed circuit. The pump section is configured to allow for pumping of heat exchange fluid at a constant pressure.
Type:
Grant
Filed:
July 25, 2003
Date of Patent:
May 10, 2005
Assignee:
Radiant Medical, Inc.
Inventors:
Timothy R. Machold, Nicole Denise Bloom, Alex T. Roth, Dave J. Scott, Jose Alejandro, Ed Oliver
Abstract: A balloon catheter, and preferably to a rapid exchange type balloon catheter, having a proximal shaft section, and a distal shaft section with an inner tubular member and an outer tubular member, the outer tubular member having a section which is bonded as by fusing or otherwise bonding. The bonded section extends along a thickened wall portion of the outer tubular member at the rapid exchange junction. A reinforcing member or tube extends within at least a section of the bonded section of the outer tubular member. In one embodiment, the reinforcing tube extends within at least a section of the thickened wall portion of the outer tubular member. The configuration provides a rapid exchange junction with improved kink resistance and flexibility for excellent trackability, and with a minimal decrease in the size of the inflation lumen at the rapid exchange junction for an improved shortened balloon inflation/deflation time.
Abstract: An embolic filtering device for use in a bifurcated vessel includes delivery device having a first guide wire and a second guide wire. The second guide wire diverges from the distal-end region of the first guide wire. The filter device also includes a filter support having a first deployment member and a second deployment member. These deployment members can be formed as a first loop and a second loop. A bifurcated filter element is coupled to the filter support. The distal-end region of the first guide wire extends through a first leg of the filter element and the second guide wire extends through a second leg of the filter element. During use, the first leg of the filter element is deployed within a first branch of the bifurcated vessel and the second leg of the filter element is deployed within a second branch of the bifurcated vessel.
Abstract: The variable stiffness heating catheter includes a heating catheter shaft including at least one electrically conductive member, a reinforcing tube with apertures formed around the surface of the reinforcing tube, and at least one coaxial outer layer of a polymer, metal, or both for providing desired variations in stiffness along at least a portion of the length of the shaft. The apertures can be formed as axial or helical slits in the surface of the reinforcing tube, and the reinforcing tube can also be formed to be tapered at the point where the apertures are formed in the reinforcing tube to provide a heating catheter that is torqueable and pushable at the proximal end, yet soft and flexible at the distal end.
Type:
Grant
Filed:
March 19, 2001
Date of Patent:
May 3, 2005
Assignee:
Micrus Corporation
Inventors:
Michael J. O'Connor, David A. Ferrera, Matthew Connors
Abstract: A manifold assembly for use in conjunction with a servicing apparatus for exchanging fluid between a serviceable automobile component and new and used fluid tanks and including a rigid manifold body with a fluid circuit defining a plurality of pathways connecting a plurality of ports whereby fluid is directed through the fluid circuit and ports by selectively operating first and second valves and circulated using a common pump to exchange fluid, recirculate fluid, and drain both the used and new fluid tanks as desired.