Patents Represented by Attorney G. W. Rauchfuss, Jr.
  • Patent number: 4061746
    Abstract: A method of treating gastrointestinal hypersecretions which comprises administering substituted lactamimide derivatives.
    Type: Grant
    Filed: April 23, 1976
    Date of Patent: December 6, 1977
    Assignee: Richardson-Merrell Inc.
    Inventors: Thomas R. Blohm, J. Martin Grisar, Norbert L. Wiech
  • Patent number: 4032647
    Abstract: Substituted thenoylacetic acid and esters, and pharmaceutically acceptable salts thereof of the following general formula are useful as hypolipidemic agents: ##STR1## wherein Y is selected from oxygen and divalent sulfur; R is selected from a straight or branched saturated hydrocarbon chain containing from 10 to 20 carbon atoms and a straight or branched unsaturated hydrocarbon chain containing from 10 to 20 carbon atoms and from 1 to 4 double bonds; R.sub.1 is selected from hydrogen and an ester group.
    Type: Grant
    Filed: June 16, 1975
    Date of Patent: June 28, 1977
    Assignee: Richardson-Merrell Inc.
    Inventor: Roger Alan Parker
  • Patent number: 4031083
    Abstract: Novel cephalosporin antibiotic derivatives.
    Type: Grant
    Filed: October 24, 1975
    Date of Patent: June 21, 1977
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: Fortuna Haviv, Abraham Patchornik, Janina Altman
  • Patent number: 3974186
    Abstract: Disclosed are novel compounds and pharmaceutical formulations having antiviral activity. The disclosed compounds have the formula ##SPC1##Wherein one R.sup.2 is a hydrogen atom and the other R.sup.2 is the radical ##SPC2##A is a straight chain alkylene group having 2 or 3 carbon atoms and each R.sup.3 and R.sup.4 is a hydrogen atom, an alkyl radical having 1 to 3 carbon atoms or each set of R.sup.3 and R.sup.4 taken together with the nitrogen atom to which they are attached is a saturated monocyclic heterocyclic group. Also included are the acid addition salts of these bases. These compounds may be prepared by various methods which are described.
    Type: Grant
    Filed: September 5, 1973
    Date of Patent: August 10, 1976
    Assignee: Richardson-Merrell Inc.
    Inventors: Robert W. Fleming, Arthur D. Sill, Francis W. Sweet
  • Patent number: 3953602
    Abstract: Compounds of the following general formula are useful in the treatment of conditions of delayed hypersensitivity: ##SPC1##Wherein X represents a bond, --CH.sub.2 --, or carbonyl; Y represents a vinylene group, ##EQU1## carbonyl, oxygen, divalent sulfur, or carbonyloxy with the proviso that when Y is ##EQU2## or vinylene, X is not carbonyl; A represents a straight or branched alkylene chain of from 1 to 6 carbon atoms with the proviso that when Y is vinylene, A contains from 1 to 5 carbon atoms and with the proviso that when Y is carbonyloxy or carbonylthio, A contains from 2 to 6 carbon atoms; each of R.sup.1 and R.sup.2 represents hydrogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms; or alkenyl of 3 to 6 carbon atoms having the vinyl unsaturation in other than 1-position; and pharmaceutically acceptable acid addition salts thereof.
    Type: Grant
    Filed: June 15, 1973
    Date of Patent: April 27, 1976
    Assignee: Richardson-Merrell Inc.
    Inventor: Irving Shemano
  • Patent number: 3931197
    Abstract: Novel compounds useful as antihistamine agents, antiallergy agents, and bronchodilators are represented by the following formula ##SPC1##Wherein R.sup.1 represents cyclohexyl, phenyl, or substituted phenyl wherein the substituent on the substituted phenyl is selected from halogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, or a lower alkoxy group of from 1 to 4 carbon atoms; R.sup.2 represents hydrogen or hydroxy; R.sup.3 represents hydrogen; or R.sup.2 and R.sup.3 taken together form a second bond between the carbon atoms bearing R.sup.2 and R.sup.
    Type: Grant
    Filed: February 8, 1974
    Date of Patent: January 6, 1976
    Assignee: Richardson-Merrell Inc.
    Inventors: Albert A. Carr, C. Richard Kinsolving