Patents Represented by Attorney Gabryleda Ferrari-Dileo

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  • (2S)-amino(phenyl)acetic acid and derivatives as ?? voltage-gated calcium channel ligands
    Patent number: 7354955
    Abstract: The present invention relates to a method for treating pain, reflex sympathetic dystrophy, spasticity, and bipolar disorder using ligands of the ?2? voltage-gated calcium channel, wherein the ligand comprises (2s)-aminophenyl acetic acid and derivatives.
    Type: Grant
    Filed: January 7, 2004
    Date of Patent: April 8, 2008
    Assignee: Abbott Laboratories
    Inventors: Chih-Hung Lee, Michael F. Jarvis
  • Benzimidazoles that are useful in treating sexual dysfunction
    Patent number: 7351828
    Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.
    Type: Grant
    Filed: October 31, 2003
    Date of Patent: April 1, 2008
    Assignee: Abbott Laboratories
    Inventors: Marlon D. Cowart, Pramila A. Bhatia, Jerome F. Daanen, Andrew O. Stewart, Meena V. Patel, Teodozyj Kolasa, Jorge D. Brioni, Jeffrey Rohde
  • Heterocyclic substituted aminoazacycles useful as central nervous system agents
    Patent number: 7332504
    Abstract: Heterocyclic substituted aminoazacyclic compounds of formula I Z-R3I, wherein Z is a defined aminoazacycle and R3 is a defined heterocycle moiety, pharmaceutical compositions of these compounds, and use of said compositions to control synaptic transmission in mammals.
    Type: Grant
    Filed: September 22, 2004
    Date of Patent: February 19, 2008
    Assignee: Abbott Laboratories
    Inventors: Michael R. Schrimpf, Kevin B. Sippy, Jerome F. Daanen, Keith Brian Ryther, Jianguo Ji
  • Cyanoamidine P2Xantagonists for the treatment of pain
    Patent number: 7241776
    Abstract: Novel cyanoamidines compounds of formula (I) and (II) and their derivatives wherein R1-R12 are as defined in the specification act as antagonists of the P2X7 receptor. These compounds are particularly useful in the treatment of pain, inflammation and neurodegeneration states.
    Type: Grant
    Filed: August 2, 2004
    Date of Patent: July 10, 2007
    Assignee: Abbott Laboratories
    Inventors: William A. Carroll, Arturo Perez-Medrano, Sridhar Peddi, Alan S. Florjancic
  • Fused bicyclic aromatic compounds that are useful in treating sexual dysfunction
    Patent number: 7235661
    Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction, wherein A, L, D and B1, are as described in the specification.
    Type: Grant
    Filed: March 31, 2006
    Date of Patent: June 26, 2007
    Assignee: Abbott Laboratories
    Inventors: Marlon D. Cowart, Steven P. Latshaw, Sherry L. Nelson, Andrew O. Stewart
  • Amides useful for treating pain
    Patent number: 7129235
    Abstract: The present invention relates to compounds of formula (I-VII) or a pharmaceutically acceptable salt or prodrug thereof, in which A, L, R6, R7 and R8 are defined herein. The present invention also relates to methods of trating pain using these compounds and pharmaceutical compositions including these compounds.
    Type: Grant
    Filed: July 8, 2004
    Date of Patent: October 31, 2006
    Assignee: Abbott Laboratories
    Inventors: Guo Zhu Zheng, Brian S. Brown, Sean C. Turner, Tammie K. White, Robert G. Schmidt, John R. Koenig, Chih-Hung Lee
  • Fused bicyclic aromatic compounds that are useful in treating sexual dysfunction
    Patent number: 7057042
    Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction, wherein A, L, D and B1 are as described in the specification.
    Type: Grant
    Filed: May 23, 2003
    Date of Patent: June 6, 2006
    Assignee: Abbott Laboratories
    Inventors: Marlon D. Cowart, Steven P. Latshaw, Sherry L. Nelson, Andrew O. Stewart
  • Amides that inhibit vanilloid receptor subtype 1 (VR1) receptor
    Patent number: 7037927
    Abstract: The present invention relates to compounds of formula (I) that are novel VR1 antagonists useful in treating pain, inflammatory thermal hyperalgesia, urinary incontinence, or bladder overactivity.
    Type: Grant
    Filed: October 16, 2003
    Date of Patent: May 2, 2006
    Assignee: Abbott Laboratories
    Inventors: Chih-Hung Lee, John R. Koenig, Brian S. Brown
  • Benzimidazoles that are useful in treating male sexual dysfunction
    Patent number: 7022728
    Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.
    Type: Grant
    Filed: March 8, 2002
    Date of Patent: April 4, 2006
    Assignee: Abbott Laboratories
    Inventors: Marlon D. Cowart, Pramila A. Bhatia, Jerome F. Daanen, Andrew O. Stewart, Meena V. Patel, Teodozyj Kolasa, Jorge D. Brioni, Jeffrey Rohde
  • Fused compounds that inhibit vanilloid subtype 1 (VR1) receptor
    Patent number: 7015233
    Abstract: Compounds of formula (I) are novel VR1 antagonists that are useful in treating pain, inflammatory thermal hyperalgesia, urinary incontinence, or bladder overactivity.
    Type: Grant
    Filed: June 12, 2003
    Date of Patent: March 21, 2006
    Assignee: Abbott Laboratories
    Inventors: Arthur Gomtsyan, Erol K. Bayburt, John R. Koenig, Chih-Hung Lee
  • Benzimidazoles that are useful in treating sexual dysfunction
    Patent number: 6960589
    Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction, wherein L is C1-4 alkyl; RA, RB, RC, RD, and RE, are as described in the specification; Z is selected from the group consisting of N, C and CH; and A is aryl and heteroaryl as described in the specification.
    Type: Grant
    Filed: September 6, 2002
    Date of Patent: November 1, 2005
    Assignee: Abbott Laboratories
    Inventors: Marlon D. Cowart, Pramila A. Bhatia, Jerome F. Daanen, Andrew O. Stewart, Meena V. Patel, Teodozyj Kolasa, Jorge D. Brioni, Jeffrey Rohde, Kenneth M. Engstrom
  • Tricyclic dihydropyrazolone and tricyclic dihydroisoxazolone potassium channel openers
    Patent number: 6780872
    Abstract: Compounds of formula I are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
    Type: Grant
    Filed: January 22, 2003
    Date of Patent: August 24, 2004
    Assignee: Abbott Laboratories
    Inventors: Irene Drizin, Robert J. Altenbach, William A. Carroll