Patents Represented by Attorney Gaetano D. Maccarone
-
Patent number: 7285219Abstract: There is described a chromatographic separation member including a substrate carrying on at least one surface a thin layer of a chromatographically active capture material. Also described is a chromatographic separation method for separating a component of interest from a fluid utilizing the chromatographic separation member.Type: GrantFiled: February 9, 2005Date of Patent: October 23, 2007Assignee: Prime Separations, Inc.Inventors: Henry S. Kolesinski, Robert S. Cooley
-
Patent number: 6812216Abstract: There are described 11-C-substituted derivatives of clarithromycin and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.Type: GrantFiled: June 25, 2002Date of Patent: November 2, 2004Assignee: Enanta Pharmaceuticals, Inc.Inventors: Ly Tam Phan, Jay Judson Farmer, Yat Sun Or
-
Patent number: 6750204Abstract: There are described 11-C-substituted derivatives of erythromycin and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.Type: GrantFiled: June 25, 2002Date of Patent: June 15, 2004Assignee: Enanta Pharmaceuticals, Inc.Inventors: Ly Tam Phan, Jay Judson Farmer, Yat Sun Or
-
Patent number: 6727229Abstract: Novel 11-12 substituted lactone ketolide derivatives and pharmaceutically-acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically-acceptable carrier are described. Also described are a method for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically effective amount of a compound of the invention and processes for the preparation of such compounds.Type: GrantFiled: August 19, 2002Date of Patent: April 27, 2004Assignee: Enanta Pharmaceuticals, Inc.Inventors: Nha Huu Vo, Ly Tam Phan, Ying Hou, Tongzhu Liu, Yat Sun Or
-
Patent number: 6720308Abstract: Novel 11-12 substituted lactone anhydrolide derivatives and pharmaceutically-acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically-acceptable carrier are described. Also described are a method for treating bacterial infections by administering to an animal a pharmaceutical composition containing a therapeutically effective amount of a compound of the invention and processes for the preparation of such compounds.Type: GrantFiled: November 7, 2002Date of Patent: April 13, 2004Assignee: Enanta Pharmaceuticals, Inc.Inventors: Nha Huu Vo, Ying Hou, Ly Tam Phan, Yat Sun Or
-
Patent number: 6680299Abstract: There are described novel 4′ substituted 16-membered macrolides and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described are a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.Type: GrantFiled: July 27, 2001Date of Patent: January 20, 2004Assignee: Enanta Pharmaceuticals, Inc.Inventors: Yat Sun Or, Ly Tam Phan, Zhaolin Wang, Tianying Jian
-
Patent number: 6673774Abstract: There are described 11-O-substituted macrolides and their descladinose derivatives and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.Type: GrantFiled: December 3, 2001Date of Patent: January 6, 2004Assignee: Enanta Pharmaceuticals, Inc.Inventors: Ly Tam Phan Phan, Deqiang Niu, Yat Sun Or
-
Patent number: 6576615Abstract: There are described novel 4′ substituted tylosin analogs and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.Type: GrantFiled: November 8, 2001Date of Patent: June 10, 2003Assignee: Enanta Pharmaceuticals, Inc.Inventors: Ly Tam Phan, Tianying Jian, Yao-Ling Qiu, Yat Sun Or
-
Patent number: 6462026Abstract: Bicyclic leucomycins and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier, a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds.Type: GrantFiled: February 16, 2001Date of Patent: October 8, 2002Assignee: Enanta Pharmaceuticals, Inc.Inventors: Yat Sun Or, Sophie Binet, Ly Tam Phan
-
Patent number: 6440942Abstract: There is described a novel class of ring contracted 14-membered macrolides, and pharmaceutically acceptable salts, esters and prodrugs thereof, having antibacterial activity, compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier as well as a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically effective amount of a compound of the invention. There are also described synthetic processes for preparing the compounds of the invention.Type: GrantFiled: December 22, 2000Date of Patent: August 27, 2002Assignee: Enanta Pharmaceuticals, Inc.Inventors: Yat Sun Or, Tsvetelina Lazarova, Sophie Binet, Jianchao Wang
-
Patent number: 6436906Abstract: Novel 9-amino-14-membered macrolides and pharmaceutically-acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier, a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention and processes for the preparation of such compounds.Type: GrantFiled: April 2, 2001Date of Patent: August 20, 2002Assignee: Enanta Pharmaceuticals, Inc.Inventors: Yat Sun Or, Nha Vo, Jianchao Wang, Ly Tam Phan
-
Patent number: 6307085Abstract: A process for generation of acid uses a medium comprising a first acid-generating component capable of generating a first acid, and a secondary acid generator, this secondary acid generator being capable of thermal decomposition to form a secondary acid, the thermal decomposition of the secondary acid generator being catalyzed by the first acid. At least part of the medium is exposed to so as to cause formation of the first acid from the first acid-generating component; and the medium is then heated to cause, in the exposed part of the medium, acid-catalyzed thermal decomposition of the secondary acid generator and formation of the secondary acid.Type: GrantFiled: July 28, 2000Date of Patent: October 23, 2001Assignee: Polaroid CorporationInventors: Jurgen M. Grasshoff, John L. Marshall, Richard A. Minns, Socorro M. Ramos, Stephen G. Stroud, Stephen J. Telfer, Haixin Yang, Roger A. Boggs, Eric S. Kolb
-
Patent number: 6258505Abstract: An imaging medium comprises a substrate carrying a color-change layer. This color-change layer comprises two layers or phases comprising two color-forming reagents which react upon heating to cause a change in the color of the layer. The color-change layer is deactivated by exposure to actinic radiation such that after deactivation it no longer undergoes its thermal color-change. The color-change layer is detachable from the substrate by heating to a temperature lower than required to cause the color change, so that upon contact of the imaging medium with a receiving sheet each individual pixel of the color-change layer may be left attached to the substrate, transferred to the receiving sheet but left uncolored, or transferred to the receiving sheet and colored to a color level determined by the energy used in the associated thermal print head element.Type: GrantFiled: March 2, 2000Date of Patent: July 10, 2001Assignee: Polaroid CorporationInventors: Jayprakash C. Bhatt, Daoshen Bi, F. Richard Cottrell, Rong C. Liang, William C. Schwarzel, Tung F. Yeh
-
Patent number: 6227729Abstract: There is described a film cassette for housing and dispensing film units of the self-developing type. The cassette includes structure which ensures that it can be inserted only in photographic apparatus particularly adapted to receive it.Type: GrantFiled: August 26, 1999Date of Patent: May 8, 2001Assignee: Polaroid CorporationInventor: Donald E. Mauchan
-
Patent number: 6221554Abstract: There is described a self-developing film unit which has a photosensitive member and an image-receiving member and wherein one outermost surface of the film unit comprises a support layer carrying a layer of a releasable material and a layer of an adhesive material. After an image is formed in the film unit by photoexposure of the photosensitive element and photographic processing of the exposed photosensitive element, the support and releasable material layer can be removed and the film unit or the image-receiving element, as the case may be, adhered to a surface for viewing of the image.Type: GrantFiled: January 6, 2000Date of Patent: April 24, 2001Assignee: Polaroid CorporationInventors: Philip R. Norris, Harry R. Parsons, William T. Plummer, Donald W. Preissler, Robert J. Wadja
-
Patent number: 6100005Abstract: There is described a novel diffusion transfer photographic system wherein an exposed diffusion transfer photographic film unit is developed with an aqueous alkaline processing composition in the presence of alumina-free titanium dioxide.Type: GrantFiled: May 29, 1998Date of Patent: August 8, 2000Assignee: Polaroid CorporationInventors: Daniel J. Churella, Wilhelm J. Erdmann, Gerard Gomes, John R. Linton, Francis M. Pierce
-
Patent number: 6001531Abstract: The present invention relates to a photographic processing composition comprising an aqueous alkaline medium including titanium dioxide particles and a stabilizing agent comprising a polymer polymerized from repeating units of styrene and an acrylic acid. The presence of the stabilizing agent substantially reduces the settling out of the titanium dioxide particles in the subject processing composition, and maintains the substantially uniform distribution of titanium dioxide particles therein. The subject processing compositions are useful in photographic diffusion transfer film units and processes.Type: GrantFiled: November 6, 1998Date of Patent: December 14, 1999Assignee: Polaroid CorporationInventors: Fariza B. Hasan, Daniel D. Huang
-
Patent number: 6000863Abstract: A method for photographic processing of an exposed photosensitive film wherein a plurality of photographic processing elements comprising a carrier layer and a photographic processing layer containing photographic processing material are brought into contact, consecutively, with the exposed photosensitive film whereby a visible image is formed in the film. Each photographic processing element is initially brought into contact with the photosensitive film with the application of pressure and the processing element and the film are allowed to remain in contact with each other for a required period of time, during which at least one, and preferably a plurality of, additional pressure applications are carried out.Type: GrantFiled: March 11, 1998Date of Patent: December 14, 1999Assignee: Polaroid CorporationInventors: Arthur H. Clough, Michael G. Dowling, David R. Gildea
-
Patent number: 5784651Abstract: A photo booth for capturing an image of a subject and providing reproductions of the image is constructed from self-contained modules--an apparatus module and a background module--linked via a roof module and a floor member. The modules can be easily bundled for handling and storing and occupy, when bundled together, a substantially smaller floor space than when the modules are secured to each other for operation as a photo booth. The apparatus module includes an image capturing device, such as a photographic camera using self-developing film, an electronic camera or a combination thereof, and an image reproduction device and may further include means for illuminating the subject, for image processing and display and for receiving payment. Means for controlling the temperature and humidity inside the apparatus module may also be provided. The apparatus module may also be used as a stand-alone unit.Type: GrantFiled: November 15, 1996Date of Patent: July 21, 1998Assignee: Polaroid CorporationInventor: Donald E. Mauchan
-
Patent number: D390678Type: GrantFiled: June 10, 1997Date of Patent: February 10, 1998Assignee: Polaroid CorporationInventor: Robert W. Matthes