Abstract: Disclosed is a method and system for identifying a location of interest between a user and an identified endpoint and computing at least one reference vector based on current positional information, current velocity information, and an identified endpoint. A sampling bandwidth is designated based on at least one of current velocity information, current positional information, and current distance to the identified endpoint. One or more locations of interest between the user and the identified endpoint are identified within the sampling bandwidth. A sampling vector is calculated for at least one of the one or more locations of interest within the sampling bandwidth, and the user is alerted to the sampling vector for the at least one location of interest within the sampling bandwidth.

Abstract: Novel crystalline forms of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2 -hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one, pharmaceutical compositions containing these crystalline forms, methods of using these crystalline forms for treating and/or preventing various microbial and/or fungal infections or disorders, and processes for obtaining these crystalline forms.

Abstract: An apparatus for determining surface topology of a portion (26) of a three-dimensional structure is provided, that includes a probing member, an illumination unit, a light focusing optics, a translation mechanism, a detector and a processor.

Abstract: High-aspect-ratio microdevices comprising microneedles, microknives and microblades and their manufacturing methods are disclosed. These devices can be used for the delivery of therapeutic agents across the skin or other tissue barriers to allow chemical and biological molecules getting into the circulation systems. The microneedles can also be used to withdraw body fluids for analysis of clinically relevant species when the device has an integrated body fluid sensor or sensor array in the vicinity of microneedles.

Abstract: This invention is based on the preparation of new solid acid triphosphates with compositions of the general formula M(IV)(HPO4)(H2PO4)2, where M(IV) is a tetravalent metal or a mixture of tetravalent metals. These compounds are insoluble in water the greater part of most organic solvents. They show a high non-water assisted protonic conductivity (about 0.01-0.04 S/cm at 100° C. and a relative humidity lower than 1%). These compounds can be used as proton conduction separators in electrochemical devices, to operate at low relative humidity values, as for example in different fuel cells, protonic pumps for electrochemical hydrogenation and dehydrogenation of organic compounds, or for hydrogen production from hydrogenated organic compounds by electro-reforming, or also for removing hydrogen from equilibrium reactions. These compounds can also be used in electrochemical sensors, in super capacitors and as acid catalysts in non-aqueous or anhydrous gaseous phases.

Abstract: The invention relates to a an incontinence strap (66) for treating urinary incontinence, in particular, urinary incontinence in females, that is configured such that it is flexible.

Abstract: The present invention relates a process of quality examining for microarray of biological material. More particularly, the present invention is directed to a process of quality examining for microarray of biological material, which comprises 1) a step for mixing probe and a compound which emits light or heat and does not react with said probe, 2) a step for microarraying the mixture obtained in step 1) on a substrate, and 3) a step for measuring light or heat emitted by the scanning of each spots of the microarray mixture.

Abstract: The present invention discloses a medicament useful for treating aseptic inflammations, containing anemonin as an effective ingredient, and use of the anemonin compound in treating aseptic inflammations. The effective ingredient in the present medicament, anemonin, can be extracted and separated from natural plants containing anemonin or its precursor. The present invention also discloses a method for preparing anemonin extract. The present medicament can be formulated into preparations for oral administration, injection and topical application, especially liquid extract, plaster, suppository, liniment, and paint etc., which can be transdermally absorbed.

Abstract: The invention relates to optically transparent compositions containing hydrophobic silicone oil and alkyl ether carboxylates that are useful e.g. as a hair treatment composition such as a shampoo. In particular, it provides an optically transparent composition comprising (a) a hydrophobic silicone oil; and (b) an alkyl ether carboxylate derived from alkanols having 6 to 22 carbon atoms; wherein the weight ratio of component (b) to component (a) is in the range of 1:1 to 20:1. The composition preferably also contains anionic surfactants as component (c), the total amount of the components (b) and (c) being preferably in the range of 10-25 wt.-% with respect to the total weight of the composition. The invention also provides a method for preparing the above composition.

Abstract: The present invention pertains to a method for manufacturing alkylate oil using a composite ionic liquid as catalyst. A mixture of isobutane and C4 olefins is used as the raw material, and a composite ionic liquid is used as catalyst to carry out an alkylation reaction. The alkane/olefin ratio in the raw material is higher than 1:1. In the composition of the aforementioned composite ionic liquid catalyst, the cations come from a hydrohalide of an alkyl-containing amine or pyridine, while the anions are composite coordinate anions coming from two or more metal compounds. One of the metal compounds is an aluminum compound, while other metal compounds are compounds of Group IB and Group IIB elements of the Periodic Table and the transition metals. The present invention also provides a design of static mixer reaction apparatus that can realize the aforementioned manufacturing method.

Abstract: The present invention relates to benzopyran derivatives substituted with secondary amines including imidazole, their preparation, and pharmaceutical compositions containing them. The present invention is pharmacologically useful for the treatment of cancer, rheumatoid arthritis, and diabetic retinopathies through anti-angiogenic properties, and also pharmacologically useful in the protection of heart and neuronal cells against ischemia-reperfusion injury or preserving organs.

Abstract: Described is a novel process for the production of at least one protein of interest by secretion of the protein of interest from a pro- or eukaryotic host cell in a compartment system, which host cell is stably expressing a secretion system and capable of heterologous secretion of the protein of interest and which compartment system has at least a first and a second compartment and wherein the host cell is located in the first compartment and wherein the first and second compartment are separated from each other by a barrier, wherein the barrier is permeable for the secreted protein of interest, but not permeable for the host cell.

Abstract: This invention relates to novel methods, kits, and devices for stopping hemorrhaging of percutaneous wounds. The inventive subject matter involves insertion of a purse-string suture around the wound, insertion of the free two ends of the suture through a tension collar, manual tightening of the tension collar until hemostasis is achieved, and application of a suture lock to the free ends of the suture to secure the tension collar and maintain hemostasis. After a sufficient period of time to allow complete hemostasis, the suture lock and the tension collar are loosened; if hemostasis has been achieved, the suture lock, the tension collar, and the suture material are removed. If bleeding continues from the wound, the tension collar is tightened and the suture lock reapplied. This process may be repeated until complete hemostasis is achieved, without the need for additional suturing or manual compression.

Abstract: The present invention relates to a novel essentially pH neutral vaginal drug delivery system suitable for modified delivery of a therapeutically active material in the vaginal cavity. The vaginal drug delivery system comprises an essentially pH neutral emulsion having globules having two phases, an internal water soluble phase and an external water-insoluble phase or film, wherein the water-soluble interior phase contains a therapeutically active drug or drugs. One novel aspect of the vaginal drug delivery system is that the internal water soluble phase comprises an acidic buffered phase.

Abstract: A two-wire sensor (6) is attached to one pole of a voltage distribution source (U) by an initial connecting line (V1) in which a current-limiting resistor (R1) is positioned and is attached to the other pole by a second connecting line (V2). Parallel to the series connection consisting of the two-wire sensor (S) and the current-limiting resistor (R1) is at least one limiting diode (D1). A current regulator (SR) which is attached to the poles of the power source (U) regulates a parallel current (I) which runs parallel to the current through the two-wire sensor (D), so that there is a sum current at the poles of the power source (U) that always corresponds to the measured value delivered by the two-wire sensor (S). The regulating inputs of the current regulator (SR) are connected to the terminals of a current-sensing resistor (R2) positioned in a connecting line (V1). When a HART®-interface is used with the two-wire sensor (S) a HART®-resistor (RH) is positioned in one of the two connecting lines (V1).

Abstract: The present invention may be embodied in a sandwich panel having first and second face panels each having a first predetermined thickness and being formed of a fiber-reinforced cementitious material. The sandwich panel further includes support frame for supporting the first and second face panels in a spaced apart configuration. The support frame is formed of a fiber-reinforced cementitious material that is continuous with the cementitious material of the first and second face panels. Blocks of rigid insulation are embedded in the sandwich panel for defining a structure of the support frame.

Abstract: Sweetness improving agents capable of improving sweetness characteristics, in particular, aftertaste characteristics. More particularly, the sweetness improving agents contain as the active ingredient a yeast extract, in particular, one containing sodium 5?-inosinate and/or sodium 5?-adenylate, sodium 5?-guanylate; sodium 5?-uridylate and sodium 5?-cytidylate, each in an amount of 1 to 15% based on the weight of the yeast extract, and 1 to 20% of sodium glutamate.

Abstract: The present invention provides a process for preparing a metal carbene complex of formula (I): wherein M is a transition metal atom selected from the group consisting of ruthenium, rhodium, iron, cobalt, osmium and iridium; L denotes neutral donor ligands ligated to said metal, such groups being the same or different; X is an anionic ligand; R1 and R2 are each independently selected from the group consisting of hydrogen, substituted or unsubstituted C1-C20 alkyl, substituted or unsubstituted C2-C20 alkenyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted vinyl, a is 2 or 3 and b is 1 or 2, such process comprising reacting a sulfur ylide of the formula Ar2S?CR1R2 or its precursor with an appropriate metal complex comprising a transition metal atom selected from the group consisting of ruthenium, rhodium, iron, cobalt, osmium and iridium, said metal complex being also

Abstract: The invention relates to a carbon dioxide fire extinguishing device comprising a capacitive measuring device (11) which is calibrated for a temperature range above and below the critical temperature of carbon dioxide and which is used to detect the amount of gas loss from a carbon dioxide pressure tank (10). The carbon dioxide fire extinguishing device comprises an outlet valve in which the capacitive measuring probe (12) is integrated in such an advantageous way that the outflow resistance of the extinguishing gas is hardly increased at all.

Abstract: In accordance with the present invention, apparatus is provided for producing power comprising a reformer for reforming a hydrocarbon material and producing syngas comprising hydrogen, carbon monoxide and carbon dioxide. Furthermore, the apparatus comprises a combustion chamber of a gas turbine unit that receives the syngas and combusts the syngas and produces flue gases comprising carbon dioxide and other gases that are supplied to the gas turbine contained in the gas turbine unit. In addition, the apparatus includes a bottoming cycle unit of a combined cycle power plant that produces power and from which combustion gases exit. A carbon dioxide separator is also included in the apparatus that receives combustion gases exiting the bottoming cycle unit and separates carbon dioxide from the other combustion gases. A compressor is provided that supplies the separated carbon dioxide to the reformer for reforming of the hydrocarbon material.