Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
Type:
Grant
Filed:
July 22, 2009
Date of Patent:
November 22, 2011
Assignee:
Abbott Laboratories
Inventors:
Yujia Dai, Steven K. Davidsen, Anna M. Ericsson, Kresna Hartandi, Zhiqin Ji, Michael R. Michaelides
Abstract: N-[4-(3-Amino-1H-indazol-4-yl)phenyl]-N?-(2-fluoro-5-methylphenyl)urea·¼ Ethanolate Crystalline Form 1, ways to make it, formulations comprising it and made with it and methods of treating patients having disease using it is disclosed.
Abstract: N-[4-(3-Amino-1H-indazol-4-yl)phenyl]-N?-(2-fluoro-5-methylphenyl)urea Hydrate Crystalline Form 1, ways to make it, formulations comprising it and made with it and methods of treating patients having disease using it are disclosed.
Type:
Grant
Filed:
October 15, 2008
Date of Patent:
May 24, 2011
Assignee:
Abbott Laboratories
Inventors:
Thomas B. Borchardt, Michael J. Rozema, Shailendra V. Bordawekar, Alexander F. Chu-Kung
Abstract: N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N?-(2-fluoro-5-methylphenyl)urea Tolueneate Crystalline Form 1, ways to make it and ways to use it are disclosed.