Abstract: Orally active benzodiazepine derivatives and their salts are disclosed. These compounds and their salts have anxiolytic and anticonvulsant activity with reduced sedative/hypnotic/muscle relaxant/ataxic effects.
Type:
Grant
Filed:
March 28, 2003
Date of Patent:
October 10, 2006
Assignee:
Wisys Technology Foundation, Inc.
Inventors:
James M. Cook, Qi Huang, Xiaohui He, Xioayan Li, Jianming Yu, Dongmei Han, Snjezana Lelas, John F. McElroy
Abstract: An adjuster having a housing or lamp housing with an adjuster portion, a gear positioned inside the housing or adjuster portion, a control rod engaged to the gear and extending from the housing or adjuster portion, and at least one tang outside the housing or adjuster portion such that the tang engages the control rod and prevents rotation thereof. As such, rotation of the gear results in linear movement of the control rod. The adjuster may be positioned on a lamp housing, or other structure.
Abstract: An enrichment article for animals. The article generally includes a platform that is suspended from the floor of a cage or other containment. The article may be a tray having a flange for suspension from the walls of a container. The platform bottom may have an opening for animal access. This article may be truncated so that is fits in one portion of the base, or may have separate compartments to accommodate not only animals, but food and or water.
Abstract: The present invention provides a complete ignition and charging system in one assembly for an internal combustion engine that includes a multiple pole radial air gap stator and flywheel assembly with ignition and regulator circuitry mounted to the stator and the flywheel having a plurality of openings extending therethrough.
Abstract: This invention provides nucleic acid sequences and characterization of the gene cluster responsible for the biosynthesis of the enediyne C-1027 (produced by Streptomyces globisporus). Methods are provided for the biosynthesis of enediynes, enediyne analogs and other biological molecules. This invention also provides enediyne and enediyne analogs biosynthesized by manipulation of the C-1027 gene pathway.
Type:
Grant
Filed:
November 12, 2002
Date of Patent:
September 12, 2006
Assignee:
Wisconsin Alumni Research Foundation (WARF)
Abstract: A disposable sheet has a draw sheet or chux attached thereto. Preferably, the chux is constructed from three layers, a bottom, middle and top layer. The top layer is moisture permeable and the middle layer is absorbent. The top layer of the chux and the sheet itself may be integrally connected. Fluids flow through the chux top layer to the middle layer. The chux bottom layer may be waterproof to prevent fluids from leaving the middle layer. A quilted pattern may be applied to the chux to for aesthetic reasons or to direct fluid flow.
Abstract: An implement support unit for cooperating with an implement-mounting device for an implement for mounting the implement on a trailer unit. Preferably, the support unit is a three point hitch type support unit.
Abstract: A lightweight and compact headlamp adjuster is constructed primarily from plastic materials. The adjuster may include a VHAD that is non-recalibratable after the headlamp aim is factory set. The adjuster includes an input shaft that engages a gear located within a housing. When the input shaft is rotated, a ball stud moves linearly to adjust the headlamp to which it is connected. The adjuster is not subject to over-adjustment when it includes a clutching mechanism provided by the interaction of the ball stud with the gear.
Abstract: A headlamp assembly including a simplified adjusting mechanism for adjusting the aim of the headlamp. The mechanism includes a gear screw that is snap fit into the headlamp housing with or without an adjuster housing. The gear screw has an O-ring in radial compression so as to ensure a good seal.
Abstract: The invention provides polypeptides and nucleic acids which identify and encode LaeA, a regulator of fungal secondary metabolite production which exhibits global control over secondary metabolite biosynthetic gene clusters. The invention further provides expression vectors, host cells, methods of increasing the production of secondary metabolites in an organism naturally producing a secondary metabolite or engineered to produce a secondary metabolite, and methods of identifying novel secondary metabolite biosynthesis gene clusters.
Abstract: A treatment for obesity and overweight comprises administering a vitamin D analog. The analog effectively inhibits an increase in body fat to animals at risk and decreases the basal fat content of animals. The treatment has a positive effect on the lean body component such that while there is an overall decrease in body weight, there is also a decrease in percent body fat. This decrease can be proportionally greater than the overall decrease in body weight. In addition, the treatment has a positive effect on bone turnover and osteogenesis making the vitamin D analog a beneficial treatment for the symptoms of menopause. Various exemplary embodiments of the treatment use the 2-alkylidene derivatives of vitamin D3, such as the 2-alkylidene-19-nor derivatives in both the R and S configurations at carbon-20.
Type:
Grant
Filed:
November 24, 2004
Date of Patent:
May 30, 2006
Inventors:
Hector F. DeLuca, Lori A. Plum, Hau Zhe Ke, Thomas A. Brown
Abstract: A connector has a female receptacle and/or a male plug, or combination thereof. The female receptacle has a sleeve for holding prongs plugged into the receptacle and a mechanism for applying pressure against the sleeve such that actuation of the collar causes the socket to clamp to the prong. The male plug has a prong for insertion into a socket or other receptacle and a mechanism for applying pressure against the prong to clamp the prong within the socket or other receptacle.