Patents Represented by Attorney Grace L. Bonner

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  • Process for preparation of fluoromethyl-substituted piperidine carbodithioates
    Patent number: 5055583
    Abstract: Described herein is a process for dehydrohalogenation of substituted dihydropyridine dicarbothioate compounds.
    Type: Grant
    Filed: March 19, 1990
    Date of Patent: October 8, 1991
    Assignee: Monsanto Company
    Inventors: Sherrol L. Baysdon, Mitchell J. Pulwer
  • Process for preparation of fluoromethyl-substituted piperidine carbodithioates
    Patent number: 5051512
    Abstract: Described herein is a process for preparation of substituted piperidine dicarbothioate compounds.
    Type: Grant
    Filed: March 19, 1990
    Date of Patent: September 24, 1991
    Assignee: Monsanto Company
    Inventors: Sherrol L. Baysdon, Mitchell J. Pulwer, Helen L. Janoski
  • Substituted thiazoles and their use as fungicides
    Patent number: 5045554
    Abstract: The present invention relates to certain substituted 5-carboxanilidothiazoles and their use as fungicides.
    Type: Grant
    Filed: October 3, 1989
    Date of Patent: September 3, 1991
    Assignee: Monsanto Company
    Inventors: Gerhard H. Alt, W. Gary Phillips, John K. Pratt, Gabriel H. Srouji
  • Method for inhibiting the polymerization of acrylic acid
    Patent number: 5034156
    Abstract: A new and improved polymerization inhibitor composition, its method of manufacture, and its use in stabilizing the distillation of acrylic acid is made possible by the pre-oxygen-activation of N-nitrosophenylhydroxylamine in combination with hydroquinone mono-methyl-ether (often referred to as p-methoxyphenol) whereupon a synergistic performance of these components is disclosed.
    Type: Grant
    Filed: January 8, 1990
    Date of Patent: July 23, 1991
    Assignee: Mallinckrodt Specialty Chemicals Company
    Inventor: John W. Varwig
  • Pyridazinone manufacture
    Patent number: 5003068
    Abstract: An improved method for the manufacture of a substituted 1,4-dihydro-4-oxopyridazine which comprises the step of reacting a glyoxyclic acid halide phenylhydrazone with 3-pyrrolidinyl-2-alkenoic acid ester.
    Type: Grant
    Filed: September 13, 1989
    Date of Patent: March 26, 1991
    Assignee: Monsanto Company
    Inventor: Thomas A. McLaughlin
  • High ibuprofen content granulations
    Patent number: 4911921
    Abstract: A granular pharmaceutical composition containing 85 to 99 percent ibuprofen, 0.9 to 15.0 percent binder, and 0.1 to 5.0 percent polyvinylpyrrolidone, wherein the polyvinylpyrrolidone forms a film with a portion of said binder to form agglomerates, is disclosed. Ibuprofen may be fluidized with a portion of the binder in a fluid bed apparatus and sprayed with an aqueous dispersion of polyvinylpyrrolidone and the remainder of the binder. This granulation may be subsequently blended with additional excipients and, optionally, additional active pharmaceutical ingredients for direct compression into tablets.
    Type: Grant
    Filed: February 2, 1989
    Date of Patent: March 27, 1990
    Assignee: Mallinckrodt, Inc.
    Inventors: Larry E. Denton, Anil M. Salepkar
  • Method of making the ethanolamine salt of N-nitrosophenylhydroxylamine
    Patent number: 4898976
    Abstract: The ethanolamine salt of N-nitrosophenylhydroxylamine ("NPHA") is effective as a polymerization inhibitor for ethylenically unsaturated monomers. The ethanolamine salt can be prepared by reacting ethanolamine with the ammonium salt of NPHA. Advantageously, the ethanolamine salt is soluble in high concentrations in water and a variety of polar organic solvents.
    Type: Grant
    Filed: April 17, 1989
    Date of Patent: February 6, 1990
    Assignee: Mallinckrodt, Inc.
    Inventor: John W. Varwig