Patents Represented by Attorney, Agent or Law Firm Grant Patent Services
  • Patent number: 6875431
    Abstract: A method for treatment of bacterial infections of the eye is disclosed which comprises a lytic enzyme composition specific for the infecting bacteria, and a carrier for delivering said lytic enzyme. The composition may be in the form of an isotonic solution.
    Type: Grant
    Filed: May 1, 2002
    Date of Patent: April 5, 2005
    Assignees: New Horizons Diagnostics Corp., Rockefeller University
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6824975
    Abstract: This invention discloses a method and composition for detecting the presence of class specific antibodies reactive with analytes such as bacteria, allergens, autoimmune antigens, viral proteins, and carbohydrates by lateral flow techniques. In one embodiment of the invention, a test sample obtained from bodily fluids reacts with a gold labeled antigen. The resulting complex travels across the membrane, and along the lateral flow strip. Red colored lines formed in specific locations along the test strip indicate the presence of class specific antibodies in the test specimen. In another embodiment of the invention, the lateral flow assay serves as an immunochromatographic screening test for the detection of allergen-specific IgE antibodies in human serum. Test sample reacts with gold labeled anti-IgE antibody. The resulting complex travels across the membrane where immobilized allergens capture the allergen specific IgE complex.
    Type: Grant
    Filed: October 12, 2001
    Date of Patent: November 30, 2004
    Assignee: Dexall Biomedical Labs, Inc
    Inventors: Thomas T. Hubscher, Glen M Ford, Teri M Ruppenthal
  • Patent number: 6752988
    Abstract: A method for the prophylactic and therapeutic treatment of bacterial infections is disclosed which comprises the treatment of an individual with an effective amount of a native or modified version of a lytic enzyme produced by a bacteria infected with a bacteriophage specific for said bacteria. The lytic enzyme is selected from a group consisting of shuffled lytic enzymes, chimericlytic enzymes, wherein the lytic enzyme is in an environment having a pH which allows for activity of said lytic enzyme; and a carrier for delivering said lytic enzyme. Additionally, a holin enzyme for puncturing the membrane may be included in the composition. This method, and composition can be used for the treatment of upper respiratory infections, skin infections, wounds, and burns, vaginal infections, eye infections, intestinal disorders and dental problems.
    Type: Grant
    Filed: April 28, 2000
    Date of Patent: June 22, 2004
    Assignees: New Horizons Diagnostic Corp, Rockefeller University
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6742780
    Abstract: This invention discloses a skateboard maze game comprising a board having a surface, an underside, a front section, and a back section at least one maze grooved into the surface of the board, at east one ball per maze which fits into the grooves, and at least one ground support element. The board is positioned on top of wheels, half wheels or some other supporting structure, allowing an individual standing on the board to move the board around to work the maze.
    Type: Grant
    Filed: December 3, 2002
    Date of Patent: June 1, 2004
    Inventor: Lewis Rudski
  • Patent number: 6737079
    Abstract: A composition for treatment of bacterial infections of burns and wounds of the skin, comprising an effective amount of at least one lytic enzyme produced by a bacteria infected with a bacteriophage specific for said bacteria, and a carrier for delivering said at least one lytic enzyme to the skin. The carrier may be, but is not limited to, a liquid solution applied to a bandage.
    Type: Grant
    Filed: August 20, 2001
    Date of Patent: May 18, 2004
    Assignees: New Horizons Diagnostics Corporation, Rockefeller University
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6733749
    Abstract: A lozenge for the treatment of Hemophilus influenzae infections of the mouth throat and nasal passage is disclosed which comprises a lytic enzyme composition specific for Hemophilus influenzae, and a lozenge carrier for delivering said lytic enzyme.
    Type: Grant
    Filed: February 27, 2002
    Date of Patent: May 11, 2004
    Assignees: New Horizons Diagnostics Corporation, Rockefeller University
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6685937
    Abstract: A chewing gum composition produced by mixing an effective amount of lysin enzyme produced by group C streptococcal bacteria infected with a C1 bacteriophage and a carrier for delivering said lysin enzyme to a mouth, throat, or nasal passage.
    Type: Grant
    Filed: May 25, 2001
    Date of Patent: February 3, 2004
    Assignees: New Horizons Diagnostics Corp., Rockefeller University
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6658188
    Abstract: A dry optical fiber cable, for voice, video and data telecommunication based on a plurality of a loosely fitted tubes placed longitudinally and surrounding a central reinforcement element, said tubes accommodating at least one or several optical fiber filaments. This dry optical fiber cable is characterized because in the internal area, between the central reinforcement element and the plurality of tubes, it has a first dry protection layer; the interior assembly is then externally protected by a second dry protection. It then has a polyethylene cover followed by the third dry protection and finally a polyethylene cover.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: December 2, 2003
    Assignee: Condumex
    Inventor: Ruben Mandujano Lopez
  • Patent number: 6642456
    Abstract: The invention relates to the manufacturing of a seven wire symmetrical hybrid conductor containing a hard copper alloy wire of copper clad steel in the center and six hard ETP copper peripheral wires in 24 and 26 AWG in sizes that fulfills the SAB J 1678 Ford specificiation with regard to electrical resistance and breaking load, having an outside diameter forming a tubular wall with very light undulations.
    Type: Grant
    Filed: December 19, 2000
    Date of Patent: November 4, 2003
    Assignee: Servicios Condumex
    Inventors: Armando Rodriguez Valadez, Belisario Sanchez Vazquez
  • Patent number: 6642293
    Abstract: A lead free polyvinyl chloride polymer composition for a thin-walled automotive cable insulation and sheath, presenting abrasion strength and thermal resistance at 105° C., characterized in that it consists of a mixture of: a polyvinyl chloride with stabilizing agents, 9 to 11 carbon atom linear co-ester type plasticizers; calcium carbonate load and at least one phenol type antioxidant agent with an oxidized polyethylene type compound.
    Type: Grant
    Filed: July 6, 2001
    Date of Patent: November 4, 2003
    Assignee: Servicios Condumey
    Inventors: Arturo Hjort Delgado, Alfonso Perez Sanchez
  • Patent number: 6635238
    Abstract: A method for the treatment and prevention of dental caries and periodontal diseases using bacteriophages and phage-encoded anti-bacterial enzymes to inhibit establishment of bacteria in the oral cavity is provided. Also provided are methods for studying the cell wall of an oral bacterium, a method for preventing spoilage of perishable items and a method for removing dextrans from surfaces utilized in sugar manufacture. Purified enzymes and the isolated DNA fragments encoding them are also provided.
    Type: Grant
    Filed: September 14, 2001
    Date of Patent: October 21, 2003
    Assignee: University of MD
    Inventor: Allan L. Delisle
  • Patent number: 6592424
    Abstract: The invention discloses colorful wind indicator toys and kites having an improved mechanism for securing a hollow rotatable rod containing mechanisms for various rotatable wind collecting parts of the wind indicators and kites. More specifically, it is proposed that a snap lock be used instead of a disk type structure to secure certain hollow rotatable rods onto the frames of wind indicator toys, thereby preventing rods from disengaging and flying away from the structure during high winds.
    Type: Grant
    Filed: July 25, 2002
    Date of Patent: July 15, 2003
    Assignee: Go Fly a Kite
    Inventor: James Christianson
  • Patent number: 6554684
    Abstract: The present invention discloses a retractable coiled toy, made of a material having a memory, which has a handle integral with the coil or body of the toy. The slinger is preferably made out of polyurethane, a coiled steel, other plastics or some other material which has memory. The present invention discloses a number of methods for using the coiled toy. The Slinger can be used to wrap around the wrist, like a bracelet. In another use, the slinger may be used as a lasso.
    Type: Grant
    Filed: February 8, 2002
    Date of Patent: April 29, 2003
    Inventor: Michael F Marlin
  • Patent number: 6528325
    Abstract: This invention discloses a method and composition for detecting the presence of class specific antibodies reactive with analytes such as bacteria, allergens, autoimmune antigens, viral proteins, and carbohydrates by lateral flow techniques. In one embodiment of the invention, a test sample obtained from bodily fluids reacts with a gold labeled antigen. The resulting complex travels across the membrane, and along the lateral flow strip. Red colored lines formed in specific locations along the test strip indicate the presence of class specific antibodies in the test specimen. In another embodiment of the invention, the lateral flow assay serves as an immunochromatographic screening test for the detection of allergen-specific IgE antibodies in human serum. Test sample reacts with gold labeled anti-IgE antibody. The resulting complex travels across the membrane where immobilized allergens capture the allergen specific IgE complex.
    Type: Grant
    Filed: October 13, 2000
    Date of Patent: March 4, 2003
    Assignee: Dexall Biomedical Labs, Inc.
    Inventors: Thomas T. Hubscher, Glen M Ford, Teri M Ruppenthal
  • Patent number: 6520824
    Abstract: A balloon toy vehicle is disclosed which has full direction control, altitude control and a motorized release feature that permits an object to be lifted and dropped remotely. Fixed tandem reversible thruster motors are positioned approximately perpendicular to the gondola body of the vehicle and work in tandem to provide forward, reverse, left turn and right turn movements. A third thruster motor is positioned along the length of the gondola body facing downward to provide lift. In a preferred embodiment, the lift thruster motor, is positioned slightly angularly from a vertical longitudinal plane passing through the gondola body and is attached to the gondola body by a bracket. This motor arrangement gives the vehicle both lift and anti-spin stability. An adjustment feature is provided to set the gondola body in a horizontal plane. This accommodates any variations in the fixed balloon connection. The vehicle is preferably operated by wireless remote control.
    Type: Grant
    Filed: June 13, 2000
    Date of Patent: February 18, 2003
    Assignee: Toytronix
    Inventor: Rom Caroselli
  • Patent number: 6509526
    Abstract: A telephone lead in cable for high performance voice, video, data transmission, and lead in services, having a generally rectangular shaped housing made of thermoplastic material, a data transmission circuit, capable of transmitting data at high speeds, that has two metal wires which are helically twisted about one another, a fusion protection thin band made of heat resistant material that is applied helically or longitudinally on the two metal wires, wherein the two metal wires are positioned to run through the center of the housing, and a circuit element for voice transmission having two metal conductors that are parallel to each other and positioned on an opposite side of the centrally located helically twisted thermoplastic covered wires.
    Type: Grant
    Filed: March 13, 2001
    Date of Patent: January 21, 2003
    Assignee: Servicies Conoumex S.A. Dec.V.
    Inventors: Victor Osornio Osornio, Fermin Marquez Arzate
  • Patent number: 6475056
    Abstract: The invention discloses colorful wind indicator toys and kites having an improved disk structure for securing various rotatable wind collecting parts of the wind indicators and kites.. More specifically, it is proposed that a hub lock be used instead of a disk type structure to secure the vanes of the wind indicator toys, therein “locking” the projections of the vanes into the hub lock, preventing the vanes or similar structures from disengaging and flying away from the structure during high winds..
    Type: Grant
    Filed: February 27, 2002
    Date of Patent: November 5, 2002
    Assignee: Go Fly A Kite
    Inventor: James David Christianson
  • Patent number: 6428784
    Abstract: A composition for treatment of bacterial infections of the vagina is disclosed which comprises a lytic enzyme composition specific for the infecting bacteria, and a carrier for delivering said lytic enzyme. The lytic enzyme is which is specific for the group B Streptococcus, is genectically coded for by a specific bacteriophage.
    Type: Grant
    Filed: September 28, 2000
    Date of Patent: August 6, 2002
    Assignee: New Horizons Diagnostics Corp
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6423299
    Abstract: An aerosol composition for treating bacterial infections of the respiratory tract by delivering said aerosol to the mouth, throat or nasal passage, wherein the bacteria to be treated is selected from the group consisting of Streptococcus pneumoniae, Haemophilus influenzae, Streptococcus Group A, and combinations thereof, said aerosol comprising an effective amount of at least one lytic enzyme genetically coded by a bacteriophage specific for a specific said bacteria of the respiratory tract, whereby said at least one lytic enzyme has the ability to digest the cell wall of said specific bacteria; and a carrier for delivering said enzyme.
    Type: Grant
    Filed: September 1, 2000
    Date of Patent: July 23, 2002
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6406692
    Abstract: A composition for treatment of bacterial infections of the eye is disclosed which comprises a lytic enzyme composition specific for the infecting bacteria, and a carrier for delivering said lytic enzyme. The carrier for delivering at least one lytic enzyme to the eye may be but is not limited to the use of an isotonic solution.
    Type: Grant
    Filed: September 28, 2000
    Date of Patent: June 18, 2002
    Assignee: New Horizons Diagnostics Corp
    Inventors: Vincent Fischetti, Lawrence Loomis