Patents Represented by Attorney, Agent or Law Firm Gregory W. Warren
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Patent number: 8247369Abstract: Methods for making a modified Cry3A toxin are disclosed. Such methods include the insertion of a protease recognition site that is recognized by a gut protease of a target insect, such as corn rootworm, into at least one position of a Cry3A toxin so that a modified Cry3A toxin is thus designed. The coding sequence of the modified Cry3A toxin may be transformed into a host cell and the host cell grown under conditions that allow the host cell to produce the modified Cry3A toxin. The host cell may be a plant cell and the plant may be comprised in a transgenic plant. Thus, the transgenic plant may be used to produce the modified Cry3A toxin.Type: GrantFiled: July 25, 2011Date of Patent: August 21, 2012Assignee: Syngenta Participations AGInventors: Eric Chen, Cheryl M. Defontes
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Patent number: 8237020Abstract: A novel pesticidal toxin that is highly active against a wide range of lepidopteran insect pests is disclosed. The DNA encoding the pesticidal toxin can be used to transform various prokaryotic and eukaryotic organisms to express the pesticidal toxin. These recombinant organisms can be used to control lepidopteran insects in various environments.Type: GrantFiled: October 1, 2009Date of Patent: August 7, 2012Assignee: Syngenta Participations AGInventors: Paul Miles, Vance Kramer, Shen Zhicheng, Gregory Warren, Frank Shotkoski
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Patent number: 8216806Abstract: Methods for making a modified Cry3A toxin are disclosed. Such methods include the insertion of a protease recognition site that is recognized by a gut protease of a target insect, such as corn rootworm, into at least one position of a Cry3A toxin so that a modified Cry3A toxin is thus designed. The coding sequence of the modified Cry3A toxin may be transformed into a host cell and the host cell grown under conditions that allow the host cell to produce the modified Cry3A toxin. The host cell may be a plant cell and the plant may be comprised in a transgenic plant. Thus, the transgenic plant may be used to produce the modified Cry3A toxin.Type: GrantFiled: July 25, 2011Date of Patent: July 10, 2012Assignee: Syngenta Participations AGInventors: Eric Chen, Cheryl Stacy
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Patent number: 8008248Abstract: Methods for making a modified Cry3A toxin are disclosed. Such methods include the insertion of a protease recognition site that is recognized by a gut protease of a target insect, such as corn rootworm, into at least one position of a Cry3A toxin so that a modified Cry3A toxin is thus designed. The coding sequence of the modified Cry3A toxin may be transformed into a host cell and the host cell grown under conditions that allow the host cell to produce the modified Cry3A toxin. The host cell may be a plant cell and the plant may be comprised in a transgenic plant. Thus, the transgenic plant may be used to produce the modified Cry3A toxin.Type: GrantFiled: June 22, 2009Date of Patent: August 30, 2011Assignee: Syngenta Participations AGInventors: Eric Chen, Cheryl M. Stacy
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Patent number: 7897748Abstract: A novel transgenic corn event designated MIR604, is disclosed. The invention relates to DNA sequences of the recombinant constructs inserted into the corn genome and of genomic sequences flanking the insertion site that resulted in the MIR604 event. The invention further relates to assays for detecting the presence of the DNA sequences of MIR604, to corn plants and corn seeds comprising the genotype of MIR604 and to methods for producing a corn plant by crossing a corn plant comprising the MIR604 genotype with itself or another corn variety.Type: GrantFiled: February 27, 2008Date of Patent: March 1, 2011Assignee: Syngenta Participations AGInventors: Henry York Steiner, Jeng S. Chen, Moez Meghji
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Patent number: 7834254Abstract: The present application relates an insect resistant transgenic cotton plant. In particular, it relates to a specific event, designated CE43-67B. The application also relates to polynucleotides which are characteristic of the CE43-67B event, plants comprising said polynucleotides, and methods of detecting the CE43-67B event.Type: GrantFiled: May 15, 2006Date of Patent: November 16, 2010Assignee: Syngenta Participations AGYInventors: Patricia J. Cayley, David V. Negrotto, Jason Barnett
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Patent number: 7803547Abstract: The present application relates to an insect resistant transgenic cotton plant. In particular, it relates to a specific event, designated COT102. The application also relates to polynucleotides which are characteristic of the COT102 event, plants comprising said polynucleotides, and methods of detecting the COT102 event. The COT 102 event exhibits a novel genotype comprising two expression cassettes. The first cassette comprises a suitable promoter for expression in plants operably linked to a gene that encodes a VIP3A insecticidal toxin, useful in controlling a vide spectrum of lepidopteran insect pests, and a suitable polyadenylation signal. The second cassette comprises a gene which, when expressed, can be used as a selectable marker.Type: GrantFiled: September 11, 2007Date of Patent: September 28, 2010Assignee: Syngenta Participations AGInventors: Daniel Murray Ellis, David Vincent Negrotto, Liang Shi, Frank Arthur Shotkoski, Carla Randall Thomas
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Patent number: 7674893Abstract: The present invention is directed to promoters isolated from maize and functional equivalents thereto. The promoters of the present invention have particular utility in driving root-specific expression of heterologous genes that impart increased agronomic, horticultural and/or pesticidal characteristics to a given promoters of the invention and transformed plant tissues containing DNA molecules comprising a promoter of the invention operably linked to a heterologous gene or genes, and seeds thereof.Type: GrantFiled: November 4, 2002Date of Patent: March 9, 2010Assignee: Syngenta Participations AGInventors: Stephen B. Milligan, Dale Skalla, Kay Lawton
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Patent number: 7615686Abstract: A novel pesticidal toxin isolated from Bacillus thuringiensis that is highly active against a wide range of lepidopteran insect pests is disclosed. The DNA encoding the pesticidal toxin can be used to transform various prokaryotic and eukaryotic organisms to express the pesticidal toxin. These recombinant organisms can be used to control lepidopteran insects in various environments.Type: GrantFiled: May 30, 2007Date of Patent: November 10, 2009Assignee: Syngenta Participations AGInventors: Paul Miles, Vance Kramer, Shen Zhicheng, Gregory Warren, Frank Shotkoski
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Patent number: 7579516Abstract: The present invention relates to isolated nucleic acid molecule comprising the untranslated region of SEQ ID NO: 1, 2 or 3. The invention also relates to chimeric genes comprising SEQ ID NO: 2 operatively linked to the coding sequence of a gene of interest and to plant transformation vectors comprising the chimeric genes of the invention. The invention further relates to transgenic plants, plant cells, plant seeds, plant tissues, or plant plastids comprising the chimeric gene.Type: GrantFiled: October 3, 2007Date of Patent: August 25, 2009Assignee: Syngenta Participations AGInventor: Eric Boudreau
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Patent number: 7569363Abstract: Methods for making a modified Cry3A toxin are disclosed. Such methods include the insertion of a protease recognition site that is recognized by a gut protease of a target insect, such as corn rootworm, into at least one position of a Cry3A toxin so that a modified Cry3A toxin is thus designed. The coding sequence of the modified Cry3A toxin may be transformed into a host cell and the host cell grown under conditions that allow the host cell to produce the modified Cry3A toxin. The host cell may be a plant cell and the plant may be comprised in a transgenic plant. Thus, the transgenic plant may be used to produce the modified Cry3A toxin.Type: GrantFiled: August 6, 2007Date of Patent: August 4, 2009Assignee: Syngenta Participations AGInventors: Eric Chen, Cheryl Stacy
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Patent number: 7521550Abstract: The present application relates to an insect resistant transgenic cotton event designated COT202. The application also relates to polynucleotides which are characteristic of the COT202 event, plants comprising the polynucleotides, and methods of detecting the COT202 event.Type: GrantFiled: November 9, 2004Date of Patent: April 21, 2009Assignee: Syngenta Participations AGInventors: David Vincent Negrotto, Frank Arthur Shotkoski, Wenjin Yu
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Patent number: 7378493Abstract: Novel Vip3C toxins that are highly active against European corn borer and other lepidopteran insect pests are disclosed. The Vip3C toxins can be expressed in various prokaryotic and eukaryotic organisms including plants to control lepidopteran insects in various environments.Type: GrantFiled: February 20, 2003Date of Patent: May 27, 2008Assignee: Syngenta Participations AGInventors: Zhicheng Shen, Gregory Warren, Vance Kramer, Frank Shotkoski
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Patent number: 7371940Abstract: The present application relates to an insect resistant transgenic cotton plant. In particular, it relates to a specific event, designated COT102. The application also relates to polynucleotides which are characteristic of the COT102 event, plants comprising said polynucleotides, and methods of detecting the COT102 event. The COT102 event exhibits a novel genotype comprising two expression cassettes. The first cassette comprises a suitable promoter for expression in plants operably linked to a gene that encodes a VIP3A insecticidal toxin, useful in controlling a wide spectrum of lepidopteran insect pests, and a suitable polyadenylation signal. The second cassette comprises a gene which, when expressed, can be used as a selectable marker.Type: GrantFiled: October 23, 2003Date of Patent: May 13, 2008Assignee: Syngenta Participations AGInventors: Daniel Murray Ellis, David Vincent Negrotto, Liang Shi, Frank Arthur Shotkoski, Carla Randall Thomas
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Patent number: 7361813Abstract: A novel transgenic corn event designated MIR604, is disclosed. The invention relates to DNA sequences of the recombinant constructs inserted into the corn genome and of genomic sequences flanking the insertion site that resulted in the MIR604 event. The invention further relates to assays for detecting the presence of the DNA sequences of MIR604, to corn plants and corn seeds comprising the genotype of MIR604 and to methods for producing a corn plant by crossing a corn plant comprising the MIR604 genotype with itself or another corn variety.Type: GrantFiled: February 16, 2005Date of Patent: April 22, 2008Assignee: Syngenta Participations AGInventors: Henry-York Steiner, Eric Chen, Moez Meghji
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Patent number: 7297839Abstract: The present invention relates to isolated nucleic acid molecule comprising the untranslated region of SEQ ID NO:2, which is functional as a promoter in plant plastids. The invention also relates to chimeric genes comprising SEQ ID NO:2 operatively linked to the coding sequence of a gene of interest and to plant transformation vectors comprising the chimeric genes of the invention. The invention further relates to transgenic plants, plant cells, plant seeds, plant tissues, or plant plastids comprising the chimeric genes.Type: GrantFiled: October 31, 2005Date of Patent: November 20, 2007Assignee: Syngenta Participations AGInventor: Eric Boudreau
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Patent number: 7276583Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel nucleic acid sequences encoding modified Cry3A toxins having increased toxicity to corn rootworm are provided. By inserting a protease recognition site, such as cathepsin G, that is recognized by a gut protease of a target insect in at least one position of a Cry3A toxin a modified Cry3A toxin having significantly greater toxicity, particularly to western and northern corn rootworm is designed.Type: GrantFiled: December 5, 2005Date of Patent: October 2, 2007Assignee: Syngenta Participations AGInventors: Eric Chen, Cheryl Stacy
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Patent number: 7244820Abstract: A novel pesticidal toxin isolated from Bacillus thuringiensis that is highly active against a wide range of lepidopteran insect pests is disclosed. The DNA encoding the pesticidal toxin can be used to transform various prokaryotic and eukaryotic organisms to express the pesticidal toxin. These recombinant organisms can be used to control lepidopteran insects in various environments.Type: GrantFiled: April 1, 2002Date of Patent: July 17, 2007Assignee: Syngenta Participations AGInventors: Paul Miles, Vance Kramer, Shen Zhicheng, Gregory Warren, Frank Shotkoski
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Patent number: 7230159Abstract: The present invention pertains to an isolated promoter sequence from Arabidopisis thaliana BOSI gene encoding a protein for biotic and abiotic stress tolerance. Also, the invention relates to recombinant vectors, expression cassettes, host cells, plants or progeny thereof comprising nucleic acid molecules operably linked to said promoter.Type: GrantFiled: March 5, 2003Date of Patent: June 12, 2007Assignee: Syngenta Participations AGInventors: Tesfaye Mengiste, Xi Chen, John Salmeron, Robert Dietrich
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Patent number: 7230167Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel nucleic acid sequences encoding modified Cry3A toxins having increased toxicity to corn rootworm are provided. By inserting a protease recognition site such as cathepsin G, that is recognized by a gut protease of a target insect in at least one position of a Cry3A toxin a modified Cry3A toxin having significantly greater toxicity, particularly to western and northern corn rootworm is designed.Type: GrantFiled: February 9, 2002Date of Patent: June 12, 2007Assignee: Syngenta Participations AGInventors: Eric Chen, Cheryl Stacy