Patents Represented by Attorney, Agent or Law Firm Gregory W. Warren
  • Patent number: 8247369
    Abstract: Methods for making a modified Cry3A toxin are disclosed. Such methods include the insertion of a protease recognition site that is recognized by a gut protease of a target insect, such as corn rootworm, into at least one position of a Cry3A toxin so that a modified Cry3A toxin is thus designed. The coding sequence of the modified Cry3A toxin may be transformed into a host cell and the host cell grown under conditions that allow the host cell to produce the modified Cry3A toxin. The host cell may be a plant cell and the plant may be comprised in a transgenic plant. Thus, the transgenic plant may be used to produce the modified Cry3A toxin.
    Type: Grant
    Filed: July 25, 2011
    Date of Patent: August 21, 2012
    Assignee: Syngenta Participations AG
    Inventors: Eric Chen, Cheryl M. Defontes
  • Patent number: 8237020
    Abstract: A novel pesticidal toxin that is highly active against a wide range of lepidopteran insect pests is disclosed. The DNA encoding the pesticidal toxin can be used to transform various prokaryotic and eukaryotic organisms to express the pesticidal toxin. These recombinant organisms can be used to control lepidopteran insects in various environments.
    Type: Grant
    Filed: October 1, 2009
    Date of Patent: August 7, 2012
    Assignee: Syngenta Participations AG
    Inventors: Paul Miles, Vance Kramer, Shen Zhicheng, Gregory Warren, Frank Shotkoski
  • Patent number: 8216806
    Abstract: Methods for making a modified Cry3A toxin are disclosed. Such methods include the insertion of a protease recognition site that is recognized by a gut protease of a target insect, such as corn rootworm, into at least one position of a Cry3A toxin so that a modified Cry3A toxin is thus designed. The coding sequence of the modified Cry3A toxin may be transformed into a host cell and the host cell grown under conditions that allow the host cell to produce the modified Cry3A toxin. The host cell may be a plant cell and the plant may be comprised in a transgenic plant. Thus, the transgenic plant may be used to produce the modified Cry3A toxin.
    Type: Grant
    Filed: July 25, 2011
    Date of Patent: July 10, 2012
    Assignee: Syngenta Participations AG
    Inventors: Eric Chen, Cheryl Stacy
  • Patent number: 8008248
    Abstract: Methods for making a modified Cry3A toxin are disclosed. Such methods include the insertion of a protease recognition site that is recognized by a gut protease of a target insect, such as corn rootworm, into at least one position of a Cry3A toxin so that a modified Cry3A toxin is thus designed. The coding sequence of the modified Cry3A toxin may be transformed into a host cell and the host cell grown under conditions that allow the host cell to produce the modified Cry3A toxin. The host cell may be a plant cell and the plant may be comprised in a transgenic plant. Thus, the transgenic plant may be used to produce the modified Cry3A toxin.
    Type: Grant
    Filed: June 22, 2009
    Date of Patent: August 30, 2011
    Assignee: Syngenta Participations AG
    Inventors: Eric Chen, Cheryl M. Stacy
  • Patent number: 7897748
    Abstract: A novel transgenic corn event designated MIR604, is disclosed. The invention relates to DNA sequences of the recombinant constructs inserted into the corn genome and of genomic sequences flanking the insertion site that resulted in the MIR604 event. The invention further relates to assays for detecting the presence of the DNA sequences of MIR604, to corn plants and corn seeds comprising the genotype of MIR604 and to methods for producing a corn plant by crossing a corn plant comprising the MIR604 genotype with itself or another corn variety.
    Type: Grant
    Filed: February 27, 2008
    Date of Patent: March 1, 2011
    Assignee: Syngenta Participations AG
    Inventors: Henry York Steiner, Jeng S. Chen, Moez Meghji
  • Patent number: 7834254
    Abstract: The present application relates an insect resistant transgenic cotton plant. In particular, it relates to a specific event, designated CE43-67B. The application also relates to polynucleotides which are characteristic of the CE43-67B event, plants comprising said polynucleotides, and methods of detecting the CE43-67B event.
    Type: Grant
    Filed: May 15, 2006
    Date of Patent: November 16, 2010
    Assignee: Syngenta Participations AGY
    Inventors: Patricia J. Cayley, David V. Negrotto, Jason Barnett
  • Patent number: 7803547
    Abstract: The present application relates to an insect resistant transgenic cotton plant. In particular, it relates to a specific event, designated COT102. The application also relates to polynucleotides which are characteristic of the COT102 event, plants comprising said polynucleotides, and methods of detecting the COT102 event. The COT 102 event exhibits a novel genotype comprising two expression cassettes. The first cassette comprises a suitable promoter for expression in plants operably linked to a gene that encodes a VIP3A insecticidal toxin, useful in controlling a vide spectrum of lepidopteran insect pests, and a suitable polyadenylation signal. The second cassette comprises a gene which, when expressed, can be used as a selectable marker.
    Type: Grant
    Filed: September 11, 2007
    Date of Patent: September 28, 2010
    Assignee: Syngenta Participations AG
    Inventors: Daniel Murray Ellis, David Vincent Negrotto, Liang Shi, Frank Arthur Shotkoski, Carla Randall Thomas
  • Patent number: 7674893
    Abstract: The present invention is directed to promoters isolated from maize and functional equivalents thereto. The promoters of the present invention have particular utility in driving root-specific expression of heterologous genes that impart increased agronomic, horticultural and/or pesticidal characteristics to a given promoters of the invention and transformed plant tissues containing DNA molecules comprising a promoter of the invention operably linked to a heterologous gene or genes, and seeds thereof.
    Type: Grant
    Filed: November 4, 2002
    Date of Patent: March 9, 2010
    Assignee: Syngenta Participations AG
    Inventors: Stephen B. Milligan, Dale Skalla, Kay Lawton
  • Patent number: 7615686
    Abstract: A novel pesticidal toxin isolated from Bacillus thuringiensis that is highly active against a wide range of lepidopteran insect pests is disclosed. The DNA encoding the pesticidal toxin can be used to transform various prokaryotic and eukaryotic organisms to express the pesticidal toxin. These recombinant organisms can be used to control lepidopteran insects in various environments.
    Type: Grant
    Filed: May 30, 2007
    Date of Patent: November 10, 2009
    Assignee: Syngenta Participations AG
    Inventors: Paul Miles, Vance Kramer, Shen Zhicheng, Gregory Warren, Frank Shotkoski
  • Patent number: 7579516
    Abstract: The present invention relates to isolated nucleic acid molecule comprising the untranslated region of SEQ ID NO: 1, 2 or 3. The invention also relates to chimeric genes comprising SEQ ID NO: 2 operatively linked to the coding sequence of a gene of interest and to plant transformation vectors comprising the chimeric genes of the invention. The invention further relates to transgenic plants, plant cells, plant seeds, plant tissues, or plant plastids comprising the chimeric gene.
    Type: Grant
    Filed: October 3, 2007
    Date of Patent: August 25, 2009
    Assignee: Syngenta Participations AG
    Inventor: Eric Boudreau
  • Patent number: 7569363
    Abstract: Methods for making a modified Cry3A toxin are disclosed. Such methods include the insertion of a protease recognition site that is recognized by a gut protease of a target insect, such as corn rootworm, into at least one position of a Cry3A toxin so that a modified Cry3A toxin is thus designed. The coding sequence of the modified Cry3A toxin may be transformed into a host cell and the host cell grown under conditions that allow the host cell to produce the modified Cry3A toxin. The host cell may be a plant cell and the plant may be comprised in a transgenic plant. Thus, the transgenic plant may be used to produce the modified Cry3A toxin.
    Type: Grant
    Filed: August 6, 2007
    Date of Patent: August 4, 2009
    Assignee: Syngenta Participations AG
    Inventors: Eric Chen, Cheryl Stacy
  • Patent number: 7521550
    Abstract: The present application relates to an insect resistant transgenic cotton event designated COT202. The application also relates to polynucleotides which are characteristic of the COT202 event, plants comprising the polynucleotides, and methods of detecting the COT202 event.
    Type: Grant
    Filed: November 9, 2004
    Date of Patent: April 21, 2009
    Assignee: Syngenta Participations AG
    Inventors: David Vincent Negrotto, Frank Arthur Shotkoski, Wenjin Yu
  • Patent number: 7378493
    Abstract: Novel Vip3C toxins that are highly active against European corn borer and other lepidopteran insect pests are disclosed. The Vip3C toxins can be expressed in various prokaryotic and eukaryotic organisms including plants to control lepidopteran insects in various environments.
    Type: Grant
    Filed: February 20, 2003
    Date of Patent: May 27, 2008
    Assignee: Syngenta Participations AG
    Inventors: Zhicheng Shen, Gregory Warren, Vance Kramer, Frank Shotkoski
  • Patent number: 7371940
    Abstract: The present application relates to an insect resistant transgenic cotton plant. In particular, it relates to a specific event, designated COT102. The application also relates to polynucleotides which are characteristic of the COT102 event, plants comprising said polynucleotides, and methods of detecting the COT102 event. The COT102 event exhibits a novel genotype comprising two expression cassettes. The first cassette comprises a suitable promoter for expression in plants operably linked to a gene that encodes a VIP3A insecticidal toxin, useful in controlling a wide spectrum of lepidopteran insect pests, and a suitable polyadenylation signal. The second cassette comprises a gene which, when expressed, can be used as a selectable marker.
    Type: Grant
    Filed: October 23, 2003
    Date of Patent: May 13, 2008
    Assignee: Syngenta Participations AG
    Inventors: Daniel Murray Ellis, David Vincent Negrotto, Liang Shi, Frank Arthur Shotkoski, Carla Randall Thomas
  • Patent number: 7361813
    Abstract: A novel transgenic corn event designated MIR604, is disclosed. The invention relates to DNA sequences of the recombinant constructs inserted into the corn genome and of genomic sequences flanking the insertion site that resulted in the MIR604 event. The invention further relates to assays for detecting the presence of the DNA sequences of MIR604, to corn plants and corn seeds comprising the genotype of MIR604 and to methods for producing a corn plant by crossing a corn plant comprising the MIR604 genotype with itself or another corn variety.
    Type: Grant
    Filed: February 16, 2005
    Date of Patent: April 22, 2008
    Assignee: Syngenta Participations AG
    Inventors: Henry-York Steiner, Eric Chen, Moez Meghji
  • Patent number: 7297839
    Abstract: The present invention relates to isolated nucleic acid molecule comprising the untranslated region of SEQ ID NO:2, which is functional as a promoter in plant plastids. The invention also relates to chimeric genes comprising SEQ ID NO:2 operatively linked to the coding sequence of a gene of interest and to plant transformation vectors comprising the chimeric genes of the invention. The invention further relates to transgenic plants, plant cells, plant seeds, plant tissues, or plant plastids comprising the chimeric genes.
    Type: Grant
    Filed: October 31, 2005
    Date of Patent: November 20, 2007
    Assignee: Syngenta Participations AG
    Inventor: Eric Boudreau
  • Patent number: 7276583
    Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel nucleic acid sequences encoding modified Cry3A toxins having increased toxicity to corn rootworm are provided. By inserting a protease recognition site, such as cathepsin G, that is recognized by a gut protease of a target insect in at least one position of a Cry3A toxin a modified Cry3A toxin having significantly greater toxicity, particularly to western and northern corn rootworm is designed.
    Type: Grant
    Filed: December 5, 2005
    Date of Patent: October 2, 2007
    Assignee: Syngenta Participations AG
    Inventors: Eric Chen, Cheryl Stacy
  • Patent number: 7244820
    Abstract: A novel pesticidal toxin isolated from Bacillus thuringiensis that is highly active against a wide range of lepidopteran insect pests is disclosed. The DNA encoding the pesticidal toxin can be used to transform various prokaryotic and eukaryotic organisms to express the pesticidal toxin. These recombinant organisms can be used to control lepidopteran insects in various environments.
    Type: Grant
    Filed: April 1, 2002
    Date of Patent: July 17, 2007
    Assignee: Syngenta Participations AG
    Inventors: Paul Miles, Vance Kramer, Shen Zhicheng, Gregory Warren, Frank Shotkoski
  • Patent number: 7230159
    Abstract: The present invention pertains to an isolated promoter sequence from Arabidopisis thaliana BOSI gene encoding a protein for biotic and abiotic stress tolerance. Also, the invention relates to recombinant vectors, expression cassettes, host cells, plants or progeny thereof comprising nucleic acid molecules operably linked to said promoter.
    Type: Grant
    Filed: March 5, 2003
    Date of Patent: June 12, 2007
    Assignee: Syngenta Participations AG
    Inventors: Tesfaye Mengiste, Xi Chen, John Salmeron, Robert Dietrich
  • Patent number: 7230167
    Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel nucleic acid sequences encoding modified Cry3A toxins having increased toxicity to corn rootworm are provided. By inserting a protease recognition site such as cathepsin G, that is recognized by a gut protease of a target insect in at least one position of a Cry3A toxin a modified Cry3A toxin having significantly greater toxicity, particularly to western and northern corn rootworm is designed.
    Type: Grant
    Filed: February 9, 2002
    Date of Patent: June 12, 2007
    Assignee: Syngenta Participations AG
    Inventors: Eric Chen, Cheryl Stacy