Abstract: A structural honeycomb panel building system including fabrication methods and equipment provides integrated, modular structural components such as floors, walls, ceilings, trusses and roof members that can replace materials conventionally used in frame buildings. The panels are substantially impervious to moisture and other environmental hazards and may be inexpensively fabricated and assembled at the building site. The structural panels are fabricated, oriented depending upon the load bearing characteristics of each individual panel, interfitted and assembled to provide an assembly of structural panels with predetermined load bearing properties.