Patents Represented by Attorney Hal Brent Woodrow
-
Patent number: 5871502Abstract: The present invention provides an improved process for manufacturing a polypropylene monofilament suture comprising aging a polypropylene filament that has been drawn in two separate drawing steps in the range of from about 4.times.to about 8.5.times.for less than two days then annealing the polypropylene filament to provide a polypropylene suture.Type: GrantFiled: April 8, 1996Date of Patent: February 16, 1999Assignee: Ethicon, Inc.Inventor: Jogendra Suryadevara
-
Patent number: 5869597Abstract: The present invention discloses polymers of poly(p-dioxanone having an inherent viscosity in the range of from 2.3 dL/g to about 8 dL/g, as determined at a concentration of 0.1 g/dL in hexafluoroisopropanol at 25.degree. C. This invention also describes improved surgical devices and filaments made from poly(p-dioxanone) with an inherent viscosity in the range of from 2.3 dL/g to about 8 dL/g, determined at a concentration of 0.1 g/dL in hexafluoroisopropanol at 25.degree. C. Additionally, disclosed are processes for manufacturing poly(p-dioxanone) with an inherent viscosity in the range of from 2.3 dL/g to about 8 dL/g, as determined at a concentration of 0.1 g/dL in hexafluoroisopropanol at 25.degree. C., as well as, processes for molding surgical articles and extruding surgical filaments from these polymers.Type: GrantFiled: June 6, 1995Date of Patent: February 9, 1999Assignee: Ethicon, Inc.Inventors: Hugh D. Newman, Jr., Dennis D. Jamiolkowski
-
Patent number: 5859150Abstract: The present invention describes a prepolymer of an aliphatic polyoxaester having a polymerizable end group that may be used to produce hydrogels, surgical devices such as sutures, sutures with attached needles, molded devices, and the like.Type: GrantFiled: November 5, 1997Date of Patent: January 12, 1999Assignee: Ethicon, Inc.Inventors: Dennis D. Jamiolkowski, Rao S. Bezwada
-
Patent number: 5855615Abstract: A composition for injecting into tissues surrounding the urethra or ureter. It comprises a plurality of physiologically acceptable solid polymer particles dispersed in a physiologically acceptable biodissipatable liquid carrier. The polymer comprises a hydrophilic component. The solid polymer particles are a glycerine insoluble poly(ethylene oxide) (PEO) polymer or copolymer or a mineral oil insoluble polyvinylpyrrolidone polymer or copolymer. The plurality of solid polymer particles are capable of hydrating and upon hydration of absorbing at least about 30% water and of swelling to a predetermined volume. The solid particles are substantially insoluble in body fluids and substantially insoluble in and non-swellable by the liquid carrier. The composition is especially suitable in treating patients with urinary incontinence and patients with vesicoureteral reflux via injection into the tissues around the urethra or ureter.Type: GrantFiled: June 7, 1996Date of Patent: January 5, 1999Assignee: Menlo Care, Inc.Inventors: Robert Steven Bley, Kevin H. Van Bladel
-
Patent number: 5855156Abstract: An apparatus and method for forming a cut end of a surgical suture tip. The apparatus including a first and second cutting dies with a channel for receiving a suture. Mechanical actuators are provided to moving the cutting dies from an open to a closed position. The cutting dies are adapted to trap and compressing the suture. A cutting blade is provided for cutting the surgical suture tip adjacent to the first and second cutting dies when the cutting dies are closed.Type: GrantFiled: May 10, 1996Date of Patent: January 5, 1999Assignee: Ethicon, Inc.Inventors: Bernd Haase, Kenneth J. Smith
-
Patent number: 5854383Abstract: Absorbable, segmented copolymers of aliphatic polyesters based on lactone monomers glycolide, trimethylene carbonate and .epsilon.-caprolactone are described. The segmented copolymers exhibit a broad range of properties, especially high strength, low modulus and fast in vivo absorption, useful in a variety of medical devices. The copolymers of the present invention have such properties, making them useful in medical devices for plastic surgery indications.Type: GrantFiled: October 6, 1997Date of Patent: December 29, 1998Assignee: Ethicon, Inc.Inventors: Modesto Erneta, Idrish A. Vhora
-
Patent number: 5844017Abstract: The present invention describes a prepolymer of aliphatic polyoxaesters containing amines and/or amido groups having polymerizable end groups that may be used to produce surgical devices such as sutures, sutures with attached needles, molded devices, and the like.Type: GrantFiled: November 17, 1997Date of Patent: December 1, 1998Assignee: Ethicon, Inc.Inventors: Dennis D. Jamiolkowski, Rao S. Bezwada
-
Patent number: 5843574Abstract: The present invention provides a new polyamide suture and a process for manufacturing this suture. The suture is made by melt extruding, quenching and drawing a polyamide filament. The polyamide filament is then wound on racks and annealed at a temperature of from about 120.degree. C. to about 185.degree. C. for at least 30 minutes. The sutures produced by this process have improved knot strength, tensile strength and stability.Type: GrantFiled: November 24, 1997Date of Patent: December 1, 1998Assignee: Ethicon, Inc.Inventors: Jogendra Suryadevara, Irandokht Irene Nozad
-
Patent number: 5844067Abstract: The present invention provides a process for producing absorbable segmented copolymers of aliphatic polyesters with a uniform sequence distribution comprising copolymerizing at least two aliphatic polyester monomers wherein one of the monomers will transesterify under copolymerization conditions to form a segmented block copolymer; then quenching the copolymerization by cooling the segmented block copolymer below the temperature at which transesterification will occur in less than 60 minutes.Type: GrantFiled: April 11, 1997Date of Patent: December 1, 1998Inventor: Modesto Erneta
-
Patent number: 5824333Abstract: The present invention provides injectable, bioabsorbable liquid copolymers suitable for use as a soft tissue repair or augmentation material in animals comprising a liquid polymer selected from the group consisting of liquid polymers of a plurality of at least two different first lactone repeating units and liquid polymers of a plurality of first lactone and second lactone repeating units; wherein the first lactone repeating units are selected from the group consisting of .epsilon.-caprolactone repeating units, trimethylene carbonate repeating units, ether lactone repeating units (which for the purpose of this invention shall mean 1,4-dioxepan-2-one and 1,5-dioxepan-2-one) and combinations thereof and the second lactone repeating units are selected from the group consisting of glycolide repeating units, lactide repeating units (which for the purpose of this invention are defined to be L-lactide, D-lactide, or D,L-lactide repeating units), p-dioxanone repeating units and combinations thereof.Type: GrantFiled: November 6, 1996Date of Patent: October 20, 1998Assignee: Ethicon, Inc.Inventors: Angelo G. Scopelianos, Rao S. Bezwada, Steven C. Arnold
-
Patent number: 5817129Abstract: The present invention provides a process and apparatus for coating sutures.Type: GrantFiled: October 31, 1996Date of Patent: October 6, 1998Assignee: Ethicon, Inc.Inventors: Samsel K. Labrecque, Vishvaroop Agarwal, Henry Pokropinski, Jr.
-
Patent number: 5817340Abstract: A solid oral dosage form for the treatment of gastrointestinal disorders comprising a therapeutically effective amount of a therapeutically effective amount of guanidinothiazole compound; and a therapeutically effective amount of an antacid wherein the pharmaceutical and an antacid are separated by a barrier which is substantially impermeable to an antacid.Type: GrantFiled: November 25, 1996Date of Patent: October 6, 1998Assignee: McNeil-PPC, Inc.Inventors: Edward John Roche, Susan Decoteau, Eleanor Freeman
-
Patent number: 5813411Abstract: A method of treating urinary disorders utilizing a physiologically acceptable composition including a plurality of physiologically acceptable hydrogel particles which have been swollen in a water solution containing a low molecular weight water soluble organic compound, the solution having the ability to swell the particles. The concentration of the organic compound is such that the resulting particles can be inserted, without use of a carrier liquid utilizing a hand driven hypodermic syringe. The swollen hydrogel particles are substantially insoluble in body fluids.Type: GrantFiled: August 20, 1996Date of Patent: September 29, 1998Assignee: Menlo Care, Inc.Inventors: Kevin H. Van Bladel, Robert S. Bley, John D. Wallace
-
Patent number: 5813303Abstract: An apparatus and method for cutting a surgical suture at a first and second different location along its length. The apparatus having a first and a second cutting die with channels for receiving at least a portion of the cross-section of the surgical suture at each location. Each of the first and second cutting dies respectively is provided with an opposing cutting die to further restraint the suture. A blade is also provided at each cutting location for cutting the suture at a point adjacent to the respective cutting dies when the suture is restrained between the sets of dies.Type: GrantFiled: May 10, 1996Date of Patent: September 29, 1998Assignee: Ethicon, Inc.Inventors: Bernd Haase, John J. Price, Kenneth J. Smith
-
Patent number: 5792181Abstract: A surgical suture comprised of a first thermally formed tip portion having a first length which is adjacent to a body portion having a second length. The first thermally formed tip portion has a generally uniform cross-section perpendicular to the first length, while the body portion has a varying cross-section which corresponds to a distribution of different cross-sectional sizes along the second length. The generally uniform cross-section of the first thermally formed tip portion has an average cross-sectional size that is less than the average of the different cross-sectional sizes along the second length.Type: GrantFiled: May 10, 1996Date of Patent: August 11, 1998Assignee: Ethicon, Inc.Inventors: Bernd Haase, John J. Price, Kenneth J. Smith, Hal B. Woodrow
-
Patent number: 5786022Abstract: The present invention provides a coating mixture composed of a solvent selected from the group consisting of ethyl acetate, ethyl acetate/ethanol, n-propyl acetate/acetone, isopropyl acetate/ethanol, ethyl acetate/acetone and blends thereof; a biocompatable polymer and optionally a fatty acid salt. The present invention also provides a process for coating surgical articles comprising forming a coating mixture, contacting a surgical article with the coating mixture; and drying the coated surgical article to substantially remove the solvent.Type: GrantFiled: October 31, 1996Date of Patent: July 28, 1998Assignee: Ethicon, Inc.Inventors: Vishvaroop Agarwal, Alastair W. Hunter
-
Patent number: 5726422Abstract: An apparatus for making a surgical suture which includes a moving clamp for griping surgical suture material. The moving clamp has a gripping state and a non-gripping state. A heating station is provided for heating a length of surgical suture material. A first actuator, coupled to the moving clamp, is provided for translating the moving clamp from a position on a first side of the heating station to a position on a second side of the heating station opposite the first side when the moving clamp is in its gripping state, and for translating the moving clamp from the position on the second side of the heating station to the position on the first side of the heating station when the moving clamp is in its non-griping state. A stationary camp is provided for gripping the surgical suture material after the first actuator has translated the moving clamp from the position on the first side of the heating station to the position on the second side of the heating station.Type: GrantFiled: May 10, 1996Date of Patent: March 10, 1998Assignee: Ethicon, Inc.Inventors: Bernd Haase, Kenneth J. Smith
-
Patent number: 5718716Abstract: We have discovered a process for producing a suture from copolymers of glycolide and .epsilon.-caprolactone comprising the steps of (a) extruding a melted copolymer of a glycolide and .epsilon.-caprolactone resin through an orifice and rapidly quenching the melted copolymer resin to produce a filament; (b) drawing the filament in the range of from about 4.times. to about 7.5.times. to produce a singly drawn filament; (c) drawing the singly drawn filament in the range of form about 1.times. to about 3.times. in a first heated zone being maintained at a temperature in the range of from about 150.degree. F. to about 450.degree. F., to form a doubly drawn filament; (d) shrinking the doubly drawn filament in the range of from about 0.75 percent to about 0.98 percent, in a second heated zone being maintained at a temperature in the range of from about 100.degree. F. to about 400.degree. F., to form a relaxed filament then rack annealing the relaxed filament to form a glycolide/.epsilon.-caprolactone suture.Type: GrantFiled: September 20, 1996Date of Patent: February 17, 1998Assignee: Ethicon, Inc.Inventors: Hwason Goddard, Kenneth M. Keilman, Oliver S. Sosely
-
Patent number: 5713920Abstract: Medical devices or components for medical devices formed from bioabsorbable elastomers comprising a random copolymer are disclosed. The random copolymer is a copolymer of from about 30 to about 70 weight percent of: a) .epsilon.-caprolactone, trimethylene carbonate, an ether lactone, or a mixture of these, and b) the balance being substantially glycolide, para-dioxanone, or a mixture of these. The random copolymers surprisingly exhibit elastomeric properties, and the copolymers are bioabsorbable. The combination of physical and biological properties of these elastomeric copolymers are particularly well-suited for numerous medical and surgical applications.Type: GrantFiled: August 7, 1995Date of Patent: February 3, 1998Assignee: Ethicon, Inc.Inventors: Rao S. Bezwada, Angelo G. Scopelianos
-
Patent number: 5703200Abstract: This invention provides various copolymers comprising a first repeating unit of the chemical formula: ##STR1## in which R.sub.1 and/or R.sub.2 are alkyl groups and a second repeating units generally having the chemical formula: ##STR2## and combinations of two or more thereof wherein R is a hydrogen atom or a methyl group and the first repeating unit is less than 45 weight percent of the total weight of the copolymer. This invention also relates to use of these copolymers in the fabrication of absorbable surgical devices such as sutures and as coatings for medical devices. Additionally, described are blends and polyoxaesters containing the first repeating unit.Type: GrantFiled: March 15, 1996Date of Patent: December 30, 1997Assignee: Ethicon, Inc.Inventors: Rao S. Bezwada, Steven C. Arnold, Constance Ace