Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.
Type:
Grant
Filed:
January 25, 2000
Date of Patent:
October 2, 2001
Assignee:
Millennium Pharmaceuticals, Inc.
Inventors:
Julian Adams, Yu-Ting Ma, Ross Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon