Abstract: A configurable tooling block for a CNC turret lathe holds a plurality of tools at a single index position of the turret. The tooling block includes a main body, a mounting flange, and a coolant manifold removably mounted on the main body on either a first side face or a second side face of the main body. The main body has a plurality of tool-receiving openings, at least one of which is a rectangular opening for receiving an OD tool. The manifold may be provided with individually operable valves for controlling coolant flow to output ports associated with the tool-receiving opening, and may be made of a material that is lighter than the material used to form the main body to reduce overall weight.

Abstract: The invention may be embodied as an identity assurance system or method. A system according to the invention may have a biometric sensor capable of providing static biometric indications, a strap capable of positioning the sensor on an organism, and a computer in communication with the sensor. The computer may have software running on the computer in order to (a) cause the computer to determine whether there is a match between a subsequent static biometric indication and an initial static biometric indication, and (b) cause the computer to send a signal indicating whether a match was determined in order to assure the identity of the organism.

Abstract: A removable cassette for a peristaltic pump includes a cassette body and an occluder disposed at least partially in the cassette body and configured to be movable between an occluding position and a non-occluding position. The occluder includes an occluder body and an anti-ejection member integrally formed on the occluder body. The anti-ejection member is configured to substantially prevent the removal of the cassette from the peristaltic pump when the occluder is in the non-occluding position.

Abstract: An orthodontic appliance including labial and lingual bodies having teeth-contacting surfaces for acting against targeted anterior teeth of a patient and associated labial and lingual components incorporating spring-loaded biasing means for causing the labial and lingual bodies to act in generally opposed directions and in unison against the surfaces of the targeted anterior teeth. Bands for attaching the appliance to molars and a lingual support component also are provided. The foregoing is applied to a fixed spring aligner, a habit appliance and a bonded crossbite appliance, as well as appliances having new and improved labial and lingual components. The habit appliance includes a labial component to pull anterior teeth into an ideal position, and the aligner and crossbite appliances include labial and lingual components for applying corrective forces to the respective labial and lingual surfaces of the anterior teeth.

Abstract: An apparatus for producing flat thin sections of a specimen (3) comprises a blade edge (7), a specimen carrier (4), a drive device (14) for producing a relative motion between the blade edge (7) and the specimen carrier (4) in a sectioning plane (5), and a light light-ribbon micrometer (8) arranged between the blade edge (7) and the specimen (3), wherein the light-ribbon micrometer (8) is arranged at a fixed distance (d) relative to the blade edge (7) and generates a light-ribbon in a plane perpendicular to the sectioning plane. A coding device (13) may be associated with the drive device (14) for controlling an alternating drive as a function of the distance (d) and of signals generated by the light-ribbon micrometer (8).

Abstract: A tissue infiltration apparatus (1) for specimens present in cassettes (5). comprises at least two liquid containers (7, 11, 13, 15) and a transport apparatus (6). A liquid having a definable property is introducible into a liquid container (7, 11, 13, 15). Multiple cassettes (5) are receivable in a transport basket (4). The transport apparatus (6) is configured in such a way that with it, at least two transport baskets (4) are transportable in the tissue infiltration apparatus (1). A transport basket (4) is deliverable to a liquid container (7, 11, 13, 15) and/or movable away from a liquid container (7, 11, 13, 15) with the transport apparatus (6). An execution sequence (21) in which the transport baskets (4) pass through the liquid containers (7, 11, 13, 15) of the tissue infiltration apparatus (1) is definable.

Abstract: Provide is a method for evaluating test agents as candidates for treating prostatic diseases, including benign prostatic hyperplasia (BPH) and androgen dependent and androgen independent prostate cancer. The method comprises providing a mouse comprising a human prostate primary xenograft, where the xenograft contains blood vessels that include human endothelial cells, initiating androgen deprivation in the mouse, administering to the mouse a test agent within a period of 1-7 days after initiating the androgen deprivation, and determining a reduction in human epithelial cells in the xenografts and/or a reduction in number of the endothelial cells or blood vessels in the xenograft. Also provided is a method for treating an individual for human prostate cancer or benign prostatic hyperplasia.

Abstract: A belt module having an intermediate section including a cross rib having a corrugated portion. The intermediate section also has a web extending along the length of the intermediate section and disposed adjacent to the cross rib. The module has a first and a second plurality of link ends extending outward from the intermediate section and having a transverse opening defined therein. The link ends are formed by a pair of spaced apart link members that are connected by a end portion. The link ends have a slot or opening defined therein from the top to the bottom of the module. The slot is bordered by the inside walls of the link members. The corrugated portion of the cross rib has a reach bar portion extending between first and second link ends and has a border portion disposed adjacent to the slot formed in the link ends.

Abstract: Provided are methods for determining whether an individual is a candidate to receive treatment with a DNA methylation inhibitor. The method can be performed a biological sample of cancerous tissue of the individual. Determining that PDEF expression is absent or low and survivin expression is present identifies the individual as a candidate to receive a treatment with a DNA methylation inhibitor. The method also includes communicating the result of identifying an individual as a candidate for receiving a DNA methylation inhibitor to a health care provider.

Abstract: A knife holder (1) for microtome blades (2) has a body (3) for reception of the blade (2) against an abutment edge (4) and a pressure plate (5) for retention of the blade, such that in the retained state, only the blade cutting edge (6) protrudes from the body (3), and an ejection apparatus (8), associated with one side edge (7) of the blade cutting edge (6), is connected to the body (3).

Abstract: One step ortho-alkylation of anilines with styrenes to give chiral anilines is obtained using a strong acid catalyst, e.g. CF3SO3H. Condensation of the product to give ligand and metallation gives complex which catalyzes polymerization of propylene to give isotactic propylene or regiorandom propylene of low PDI or blocks thereof, depending on polymerization temperature.

Abstract: A topping dispenser for dispensing serving portions of topping onto beverages and desserts comprises a housing having a front product compartment and a rear drive compartment separated by a partition. The product compartment is adapted to receive a pastry bag containing topping such that the bag is suspended against the partition, and a vertically displaceable roller is provided in the product compartment to roll down along the partition to squeeze contents of the bag out through a bottom dispensing tip of the bag that extends through an opening in the housing to direct product onto a waiting beverage. The roller is advanced downward in predetermined increments by a pawl drive mechanism located in the drive compartment and coupled to the roller by a mounting bracket extending through travel slots in the partition. The pawl drive mechanism is actuated by an operating lever pivotally mounted on the housing.

Abstract: A flexible diagnostic workstation comprises is equipped to read label information on well strips of loaded well plates and on loaded reagent kit holders, automatically perform the pre-analytical steps of an immuno-assay which consists of a sequence of operations in accordance with scheduled test requirements for each microwell, read the results according to either a standard singleplex ELISA or multiplex test format as indicated by the well strip label, and report the results.

Abstract: Provided are methods and compositions for inhibiting expression of one or more target genes. The compositions contain RNA polynucleotides that can inhibit expression of a target gene via RNA interference (RNAi) electrostatically complexed with surface functionalized gold nanorods (GNRs). The RNA polynucleotides are not covalently bound to the surface functionalized GNRs. The method involves inhibiting expression of a target gene in an individual. The method is performed by administering to the individual an effective amount of a composition containing surface functionalized GNRs electrostatically complexed with RNA polynucleotides, such as siRNA, that can inhibit expression of the target gene via RNAi. The siRNA is not covalently bound to the surface functionalized GNRs.

Abstract: Preparation of cryocooled protein crystal is provided by use of helium pressurizing and cryocooling to obtain cryocooled protein crystal allowing collection of high resolution data and by heavier noble gas (krypton or xenon) binding followed by helium pressurizing and cryocooling to obtain cryocooled protein crystal for collection of high resolution data and SAD phasing simultaneously. The helium pressurizing is carried out on crystal coated to prevent dehydration or on crystal grown in aqueous solution in a capillary.

Abstract: A cable hoisting apparatus for loading and unloading of containers with respect to vehicles including a modular assembly allowing the apparatus to be easily attached or detached with respect to the vehicle. This modular assembly includes a subframe directly attachable detachably to the vehicle which includes a reeve cylinder and a lifting cylinder mounted therewithin. A top frame is included which is pivotally movably mounted to the subframe. The lifting cylinder powers pivotal movement of the top frame. Loading and unloading of the container is powered by the reeve cylinder. The reeve cylinder moves a shoe within a shoe track which extends or contracts a cable attached to a container which is positioned about a plurality of sheaves one of which is attached to the slideable shoe. A positively engaging locking construction is included defined between the subframe and the top frame for positively retaining the container.

Abstract: An illumination device for a light microscope with an objective, in particular for a stereo-microscope, illuminates an object plane of the light microscope. An illumination beam path of the illumination device is defined by a light source, a field diaphragm, illumination optics with at least one illumination lens, and at least one deflection element. The object plane of the microscope is obliquely illuminated with incident illumination, wherein an axis of the illumination beam path forms an angle ? greater than 0° with an optical axis of the objective.

Abstract: According to one aspect of the present invention there is provided a creeper, comprising a generally rectangular frame. Two sides of the frame may each comprise a plurality of telescoping members. Wheels may depend from the frame. A flexible covering may be provided, affixed to and generally filling said frame. The telescoping members can be positioned in at least two configurations, including a first, operating configuration where the frame is fully extended and usable as a creeper, and a second, storage configuration where the frame is fully retracted, and wherein the flexible covering does not need to be removed from the frame when the creeper is changed from the operating configuration to the storage configuration.

Abstract: A microscope having a night vision apparatus, which apparatus can be impinged upon by beam paths proceeding from a specimen or object to be observed.