Patents Represented by Attorney J.P. Mc Laughlin

Find this attorney in the Justia Lawyer Directory

  • Immobilized metal, affinity chromatography
    Patent number: 5932102
    Abstract: A method for purifying protein containing histidine residues using immobilized metal, affinity chromatography. The hydrophilic index of the histidine residues is determined (HI). If the HI is at least 2 the pH of the solution containing the protein is adjusted to about 6.75 to 7.2 and applied to the IMAC column such that the protein binds to the column.
    Type: Grant
    Filed: January 12, 1998
    Date of Patent: August 3, 1999
    Assignee: Schering Corporation
    Inventors: David C. Wyllie, John Chu-Tay Tang