Abstract: Compounds are provided that inhibit the interaction of an IGF with any one of its binding proteins and not to a human IGF receptor. These IGF agonist compounds, which include peptides, are useful to increase serum and tissue levels of active IGFs in a mammal.
Type:
Grant
Filed:
November 28, 2000
Date of Patent:
January 27, 2004
Assignee:
Genentech, Inc.
Inventors:
Ross G. Clark, Henry B. Lowman, Iain C. A. F. Robinson
Abstract: Compounds are provided that inhibit the interaction of an IGF with any one of its binding proteins and not to a human IGF receptor. These IGF agonist compounds, which include peptides, are useful to increase serum and tissue levels of active IGFs in a mammal.
Type:
Grant
Filed:
November 28, 2000
Date of Patent:
January 20, 2004
Assignee:
Genentech, Inc.
Inventors:
Ross G. Clark, Henry B. Lowman, Iain C. A. F. Robinson
Abstract: Compounds are provided that inhibit the interaction of an IGF with any one of its binding proteins and not to a human IGF receptor. These IGF agonist compounds, which include peptides, are useful to increase serum and tissue levels of active IGFs in a mammal.
Type:
Grant
Filed:
November 28, 2000
Date of Patent:
January 13, 2004
Assignee:
Genentech, Inc.
Inventors:
Ross G. Clark, Henry B. Lowman, Iain C. A. F. Robinson
Abstract: Compounds are provided that inhibit the interaction of an IGF with any one of its binding proteins and not to a human IGF receptor. These IGF agonist compounds, which include peptides, are useful to increase serum and tissue levels of active IGFs in a mammal.
Type:
Grant
Filed:
November 28, 2000
Date of Patent:
November 11, 2003
Assignee:
Genentech, Inc.
Inventors:
Ross G. Clark, Henry B. Lowman, Iain C. A. F. Robinson
Abstract: Compounds are provided that inhibit the interaction of an IGF with any one of its binding proteins and not to a human IGF receptor. These IGF agonist compounds, which includes peptides, are useful to increase serum and tissue levels of active IGFs in a mammal.
Type:
Grant
Filed:
November 28, 2000
Date of Patent:
October 21, 2003
Assignee:
Genentech, Inc.
Inventors:
Ross G. Clark, Henry B. Lowman, Iain C. A. F. Robinson
Abstract: Compounds are provided that inhibit the interaction of an IGF with any one of its binding proteins and not to a human IGF receptor. These IGF agonist compounds, which include peptides, are useful to increase serum and tissue levels of active IGFs in a mammal.
Type:
Grant
Filed:
November 28, 2000
Date of Patent:
September 16, 2003
Assignee:
Genentech, Inc.
Inventors:
Ross G. Clark, Henry B. Lowman, Iain C.A.F. Robinson