Patents Represented by Attorney Jenkins, Wilson, Taylor & Runt, P.A.
  • Patent number: 8158128
    Abstract: The present invention provides progastrin-binding molecules specific for progastrin that do not bind gastrin-17(G17), gastrin-34(G34), glycine-extended gastrin-17(G17-Gly), or glycine-extended gastrin-34(G34-Gly). Further, the invention provides monoclonal antibodies (MAbs) selective for sequences at the N-terminus and the C-terminus of the gastrin precursor molecule, progastrin and the hybridomas that produce these MAbs. Also provided are panels of Mabs useful for the detection and quantitation of progastrin and gastrin hormone species in immuno-detection and quantitation assays. These assays are useful for diagnosing and monitoring a gastrin-promoted disease or condition, or for monitoring the progress of a course of therapy. The invention further provides solid phase assays including immunohistochemical (IHC) and immunofluorescence (IF) assays suitable for detection and visualization of gastrin species in solid samples, such as biopsy samples or tissue slices.
    Type: Grant
    Filed: September 21, 2005
    Date of Patent: April 17, 2012
    Assignee: Cancer Advances, Inc.
    Inventor: Stephen Grimes
  • Patent number: 7014743
    Abstract: A method for depositing a nanostructure-containing material onto an object or substrate includes one or more of the following: (1) forming a solution or suspension of nanostructure-containing material, (2) selectively adding “chargers” to the solution, (3) immersing electrodes in the solution, the substrate or object upon which the nanostructure material is to be deposited acting as one of the electrodes, (4) applying a direct and/or alternating current electrical field between the two electrodes for a certain period of time thereby causing the nanostructure materials in the solution to migrate toward and attach themselves to the substrate electrode, and (5) subsequent optional processing of the coated substrate. Associated objects and devices are also provided. A method for separating nanostructures based on their properties and/or geometry is also described.
    Type: Grant
    Filed: December 9, 2003
    Date of Patent: March 21, 2006
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Otto Z. Zhou, Jie Tang, Huaizhi Geng, Lu-Chang Qin, Jian Zhang, Guang Yang