Abstract: The present invention pertains to compositions having improved delivery of pharmaceutical actives. These compositions comprise pharmaceutical actives in an anhydrous solvent. These compositions may take the form of liquid elixirs placed into the mouth and eventually swallowed, or can be delivered via liquid-filled drops, metered liquid dosing devices, atomizers and liquid-releasing, edible capsules.

Abstract: The present invention relates to a per oral, oral, or intranasal pharmaceutical mucoretentive, aqueous liquid composition comprising from about 2% to about 50%, by weight of the composition, of colloidal particles of silica, titanium dioxide, clay, and mixtures thereof and a safe and effective amount of a pharmaceutical active selected from the group consisting of analgesics, decongestants, expectorants, antitussives, antihistamines, sensory agents, gastrointestinal agents, and mixtures thereof; wherein the composition has a sedimentation volume ratio of greater than about 0.90 and wherein the triggered viscosity ratio of the composition is at least about 1.2. The present invention further relates to a method of coating the alimentary canal and nasal mucosa, in particular to a method of preventing or treating symptoms of upper respiratory tract infections or upper respiratory tract tissue irritation or damage, by administering a safe and effective amount of the above composition.

Abstract: A single- or multi-ply disposable wiping article is disclosed. The disposable wiping article comprises at least one web layer and has a surface topography exhibiting regions of minimum and maximum calipers. A continuous polymer network defining bonded regions and a plurality of unbonded regions is bonded to the web layer. The continuous polymer network is preferably a thermoplastic adhesive. After curing, the thermoplastic adhesive can contract upon heating, thereby creating puckered regions of maximum caliper coincident unbonded regions. The minimum caliper of the web layer is coincident the bonded regions. Methods of making the web of the present invention are disclosed. One method includes providing a first web layer; providing a thermoplastic adhesive; applying the thermoplastic adhesive to the first web layer in a continuous network; curing the thermoplastic adhesive; and heating the thermoplastic adhesive to effect contraction of the thermoplastic adhesive.

Abstract: The present invention is an absorbent structure with an ultimate fluid storage member, comprising superabsorbent material at a relatively high concentration whereby the superabsorbent material has a good Performance under Pressure performance as well as a good Saline Flow conductivity. Further, the absorbent structure comprises a non-woven wrap sheet comprising small diameter fibers, which is in direct fluid communication with said storage member, and which has low strike-through times in a repeated modified strike through test.

Abstract: The present invention covers pourable liquid vehicles that can be combined with compositions, materials and substances. Among the benefits of such pourable liquid vehicles is the compositions are retained on the moistened surface for a period of time sufficient to allow compositions, materials and substances to act on said surface, resisting erosion or run-off from additional moisture being applied. Such pourable liquid vehicles have a number of utilities including but not limited to cleaning and treating surfaces of objects as well as biological or living organisms, including living creatures.

Abstract: The present invention is directed to an antimicrobial hydrogel-forming absorbent polymer comprising a hydrogel-forming absorbent polymer, and an antimicrobial comprising a 1-hydroxy-2-pyrrolidone derivative represented by the formula (I); wherein R1 represents an alkyl group having 1-17 carbon atoms, alkenyl group having 2-17 carbon atoms, cycloalkyl group having 5-8 carbon atoms, bicycloalkyl group having 7-9 carbon atoms, cycloalkyl-alkyl group wherein the alkyl group has 1-4 carbon atoms and the cycloalkyl group may be substituted with an alkyl group having 1-4 carbon atoms, aryl group, aralkyl group with an alkyl group having 1-4 carbon atoms, aryl-alkenyl group with the alkenyl group having 2-4 carbon atoms, aryloxyalkyl or arylmercaptoalkyl group with the alkyl group having 1-4 carbon atoms, benzhydryl group, phenylsulfonylalkyl group with the alkyl group having 1-4 carbon atoms, furylalkenyl group with the furyl or alkenyl group having 2-4 carbon atoms, wherein the above-mentioned ary

Abstract: The present invention relates to a dispensing device (1) for a fluid (10), the dispensing device (1) comprising a reservoir (11), a shaft (12), a back seal (13), a damper (14), a piston (151) and a one-way valve (16), the back seal (13) sealing a first end of the reservoir and being displaceable along the shaft, the valve being on the second end of the reservoir, the piston being fixed to one end of the shaft, the piston being located between the valve and the damper, the damper being also fixed to the shaft, the damper being located between the piston and the back seal, whereby the piston has an opened position (151) and a closed position (152), the open position allowing fluid communication between the valve and the pat of the reservoir between the piston and the back seal, the displacement of the piston between the opened and the closed position being induced by a displacement of the shaft along its own axis, the pressure in the area comprised between the valve and the piston reducing when the piston is mo

Abstract: A throat drop comprises from 60% to 95% of an edible shell and from 5% to 40% of an aqueous filling, by weight of the drop. The filling contains a throat relief agent, from 8% to 95%, by weight, water and from 0.001% to 10%, by weight, of a vesicle-forming agent which encapsulates the throat relief agents with vesicles which are dispersed within the filling. The vesicles have a number average particle size of from about 1 to about 100 &mgr;m.

Abstract: Oral compositions containing therapeutical agents wherein the undesirable consumer aesthetics associated with these agents are mitigated using coolants and sweeteners.

Abstract: This invention is a disposable absorbent article (20) covering certain parts of the body of the wearer and comprising a loading area, a storage area, as well as a chassis area, whereby the absorbent article has a specific skin hydration value, calculated from the individual skin hydration values of the respective areas.

Abstract: Disclosed is an absorbent article comprising an absorbent core with a crotch region and at least one waist region, whereby said crotch region has a lower ultimate fluid storage capability than said at least one waist region. The crotch region further comprises a high flux liquid distribution material having a flux at 12.4 cm of more than 0.075 g/cm2/sec.